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Lab-grown human muscle showed benefits of exercise

Tissue engineered muscle under simulated exercise prevented chronic inflammation

29-Jan-2021

Key points from article :

Inflammation for months or years can cause chronic inflammatory diseases.

"Found that exercising muscle cells can autonomously prevent inflammatory effects," - Nenad Bursac, study co-author.

First to engineer contracting, functional human skeletal muscle in a Petri dish.

Putting the muscle through a simulated exercise, on top of exposing the tissue to interferon-gamma.

Designed to mimic the effects of a long-lasting chronic inflammation.

Exercise had a profoundly protective effect, almost completely preventing the negative effects of chronic inflammation.

"Exercise directly attenuates a molecular signaling pathway upregulated by inflammation." - Bursac.

WHO recommends 150-300 minutes of moderate activity or 75-150 minutes of vigorous activity a week.

People should also lift weights or do resistance exercise two or more days a week.

Staying active and stress-free helps stave off excessive inflammation.

Research by Duke University published in the journal Science Advances.

Mentioned in this article:

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Duke University

Private research university in Durham, North Carolina

Nenad Bursac

Professor of Biomedical Engineering at Duke University

Science Advances

Journal that publishes original research and reviews in all disciplines of science

Topics mentioned on this page:
Exercise, Inflammaging