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Clearing the Body’s Retired Cells Slows Aging and Extends Life

03-Feb-2016

Key points from article :

Cells accumulate damage in their DNA.

Eventually become senescent – i.e. they stop dividing – and are characterized by protein p16.

Team developed a way of singling out and removing those cells – increased lifespan of mice by a quarter.

Possibly “one of the more important aging discoveries ever.”

Have made an old organism physiologically younger – treatment instead of prevention.

Mentioned in this article:

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Darren Baker

Molecular biologist at Mayo Clinic.

Jan van Deursen

Professor of Biochemistry and Molecular Biology and Professor of Pediatrics at The Mayo Clinic.

Judith Campisi

Professor of biogerontology and Biochemist.

Mayo Clinic

Non-profit American academic medical center focused on health care, education, and research

Nathaniel David

Co-Founder and President, Unity Biotechnology

Norman Sharpless

Director at UNC Lineberger Comprehensive Cancer Center.

Topics mentioned on this page:
Senescent Cells