Key points from article :
Telomeres and Telomerase Group uncovered one of the epigenetic signals in the pluripotent cells.
Single change at telomeres controls the ability of cells to generate a complete organism.
DNA of telomeres directs the production of long RNA molecules called TERRAs.
TRF1 protein is the on/off switch that regulates TERRAs.
TERRA molecules, produced in telomeres, interact with Polycomb, together they're involved in telomere structure.
TERRA is the link between TRF1 and pluripotency.
Result is published in the journal eLife.
