Key points from article :
Generating energy can potentially save tissue from stroke. But that’s just scratching the surface.
Nanobioreactors are a new way to tinker with the inner workings of the cell.
Mitochondria functions go down in diseases like stroke or cancer, or even as we age.
Exosomes are great wrappers to stuff in chemical ingredients to mimic an organelle.
Researchers dotted the surface of the exosome wrappers with a molecule, catechol, that grabs onto metal ions.
Catechol was then linked with different protein “zip codes” that direct the exosome to specific cells.
Wrappers were then purified and each re-stuffed with two separate, different chemicals.
Exosomes were pulled close to each other and fused into one giant blob.
Two chemicals blended, and voilà—the newly-minted artificial organelle lit up with fluorescence.
Team stuffed four proteins and chemicals into exosome bioreactors, helps synthesize ATP.
Research by Ulsan National Institute of Science and Technology, led by Yoon-Kyoung Cho, published in Nature Catalysis
