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LEAF interviews Daria Khaltourina about WHO classification of ageing

05-May-2020

Key points from article :

Her team recommended WHO gives aging its own disease classification in the ICD-11.

Concluded that aging fits the WHO definition of a disease from numerous standpoints:

1. several key pathological processes behind aging identified

2. some interventions have been proved effective (e.g. lifestyle changes, drugs)

3. aging is firmly linked to certain genetic & environmental factors

WHO introduced a new extension code – “Aging-related” – in the “Causality” section.

Lack of ICD code has hampered investment into longevity research and development.

e.g. immunosenescence treatment will fall under “Aging-related acquired immunodeficiencies” - could be recommended to everybody over 60.

As more clinical data emerges, hopefully WHO will promote to a broader category.

Need a consensus on which biomarkers of aging to be used in clinical trials.

Lack of clinical trials is blocking effective anti-aging therapies.

Pathological changes should not be considered normal whenever they occur.

Believes life extension treatments may already exist - but need more clinical trials

Mentioned in this article:

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Academic

Founding Member of International Longevity Alliance. Promoted aging as an ICD11 disease as WHO.

Institute

Specialized agency of the United Nations responsible for international public health