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Oral senolytics have big impact on old mice

Senolytic cocktail caused improved physical condition of elderly mice

09-Jul-2018

Key points from article :

Senolytic drugs in elderly mice improved health and extended life.

Mayo Clinic study looked at dasatinib and quercetin.

Quercetin is an antioxidant found in apples and other foods.

Oral administration of senolytics improved physical function in old mice.

Remaining life span was extended by 36 percent at human equivalent of 80 years.

Conversely, transplanting senescent cells into young mice reduced survival.

Only small numbers of cells needed to have an effect.

The study was published in the Nature Medicine journal.

Mentioned in this article:

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James Kirkland

Researcher on different aging related diseases

Mayo Clinic

Non-profit American academic medical center focused on health care, education, and research

Nature Medicine

Scientific Journal providing information from all areas of medicine

Topics mentioned on this page:
Senescent Cells