Key points from article :
Professor Richard Faragher is Professor of biological gerontology at the University of Brighton.
Faragher’s early work led him to explore genetic diseases, including Werner’s syndrome.
Mechanisms that cause senescence in Werner’s syndrome were largely the result of telomere shortening
Culturing cells starts with 99% growing and 1% senescent and it slowly swaps.
There are scenarios in which you really wouldn’t want to get rid of senescent cells.
Removing senescent cells from endothelial layer of cornea could result in blindness.
Survivors would spread out - need to be able to revert senescent cells to normal instead.
Developed a new synthetic route for resveratrol-type compounds which started them growing again.
Resveratrol gives these cells a little puff of telomerase, opening up the telomere so that it can be repaired.
The biggest mistake that you can make is to assume that you’ve got some kind of cure-all.
