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First-in-human, FDA-approved clinical trial to test a hydrogel on cardiac tissue

Positive results seen in patients who had a heart attack more than a year before

12-Sep-2019

Key points from article :

Injectable hydrogel aims to repair damage and restore cardiac function in heart failure patients.

Hydrogel is made from the natural scaffolding of cardiac muscle tissue.

VentriGel can be safely injected into patients who had suffered a heart attack in the past 2 to 36 months.

Once injected, VentriGel forms a scaffold that acts as a reparative environment where healthy cells migrate.

Future phase 2 clinical trial will evaluate how effectively VentriGel can improve cardiac function.

Findings were published in the Journal of the American College of Cardiology.

Phase 1 clinical trial is done by the Ventrix, a spin-off company of University of California.

Mentioned in this article:

Click on resource name for more details.

Journal of the American College of Cardiology (JACC)

Scientific Journal providing information about cardiovascular diesases.

Karen L. Christman

Professor of Bioengineering and Associate Dean for Faculty Affairs and Welfare at UC San Diego Jacobs School of Engineering

VentriGel

Biomaterial designed for repair of damaged cardiac muscle.

Ventrix

Company that produces biomaterial for cardiac repair for patients who had heart attack.

Topics mentioned on this page:
Heart Disease, Regenerative Medicine