Key points from article :
Scientists have regenerated hair follicles from human stem cells.
Through near-complete skin organoids — self-organizing tissues grown that mimic developing skin.
They sequentially added growth factors to the stem cells then grew in a sphere.
After more than 70 days, follicles began to appear, which ultimately produced hair.
Tissues, muscles, fats associated with hair follicles present, immune cells absent.
Found that their organoids expressed genes characteristic of skin from chin, cheek and ear.
Altering culture conditions can generate skin characteristic of different body sites.
Transplanted organoids onto immunodeficient mice (to ensure the graft was not rejected).
Showed that over half of organoids go on to form hair and is distributed across graft.
Took 140 days before organoids were ready for engraftment, hair produced were small.
Research from Boston Children's Hospital, Indiana University School of Medicine.
Also from Stanford University, published in Nature.
