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Fisetin destroys senescent cells, but safe dosage not determined yet

Includes table of fisetin content in range of fruits and vegetables


Key points from article :

Fisetin is a naturally occurring flavonol and also acts as a pigment.

Strawberries have the highest fisetin content at 160 micrograms per gram (µg/g).

Typical supplement pills are in the 100 mg (milligrams) range - though no safe range defined yet.

Studies show that it has anti-inflammatory and neuroprotective properties in animals,

Targets and destroys senescent cells rather than simply blocking their signals or altering them.

LEAF suggests waiting for results of clinical trials to determine correct dosage before taking fisetin.

The studies were published in the EBioMedicine and PubMed journals.

Mentioned in this article:

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Medical journal covering all fields in the biomedical research

James Kirkland

Researcher on different aging related diseases

Jan van Deursen

Professor of Biochemistry and Molecular Biology and Professor of Pediatrics at The Mayo Clinic.

Mayo Clinic

Non-profit American academic medical center focused on health care, education, and research

Paul Robbins

Professor of Biochemistry, Molecular Biology and Biophysics at the University of Minnesota

PubMed Central (NCBI)

PubMed Central is a full text repository, which contains the full text of publications in the database

Salk Institute

Scientific research institute focused on neuroscience, genetics, immunology, plant biology and more

Topics mentioned on this page:
Senescent Cells, Supplements