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Highlights from eLife's Aging, Geroscience and Longevity Symposium


Key points from article :

Peter Fedichev - GERO

Burden of rarest protein-truncating variants (PTVs) is negatively associated with human lifespan, accounting for 1.3 years variability.

Sara Hägg - Karolinska Institutet

Developed nine measurements of biological age.

Dario Riccardo Valenzano - Max Planck Institute for Biology of Ageing

Limited population size ... exacerbates the effects of mutation accumulation and cumulatively contribute to short adult lifespan.

Jonathan An - University of Washington

Bridging the interface of aging biology and oral biology to extend the oral healthspan in people.

Mounir El Maï - IRCAN

Inhibition of FoxO transcription factors by Akt indirectly induce p15/16 growth arrest and senescence.

Morgan Levine - Yale School of Medicine

Reduced representation bisulfite sequencing (RRBS) data was used to train an epigenetic age (DNAmAge) measure in rats.

Dudley Lamming - University of Wisconsin-Madison

Ovariectomized female mice have improved survival despite increased adiposity and decreased control of blood glucose levels.

Amanda Kowalczyk - Carnegie Mellon University – University of Pittsburgh

Pan-mammalian analysis finds that effective cancer control is a key adaptation underlying the evolution of extreme longevity.

Michael Polymenis - Texas A&M University

Loss of one-carbon (1C) enzymes increased the longevity of wild type cells.

Nicole Jenkins - University of Melbourne

Changes in ferrous iron and glutathione promote ferroptosis and frailty in aging C. elegans.

Hosni Cherif - McGill University

Potential of senolytic compounds to remove senescent intervertebral disc (IVD) cells, reducing the inflammatory environment and pain.

Fivos Borbolis - Academy of Athens

Critical and conserved function of DCAP-1/DCP1 in lifespan modulation and control of developmental events.

Ying Ann Chiao - Oklahoma Medical Research Foundation

Mitochondrial-targeted peptide SS-31 (elamipretide) can substantially reverse pre-existing cardiac dysfunction in old mice.

Authors covered biological age clocks, senescent cells, longevity genes, and more

Mentioned in this article:

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Ph.D. Candidate in Computational and Systems Biology at the University of Pittsburgh.


Group leader at the Max Planck Institute for Biology of Ageing.


Associate Professor Of Medicine at University of Wisconsin-Madison.


Non-profit journal publishing work in all areas of biology and medicine


Postdoctoral Researcher at Biomedical Research Foundation of the Academy of Athens.


Postdoctoral Fellow at McGill University.


Assistant Professor at University of Washington School of Dentistry.


Professor of Biochemistry & Biophysics at Texas A&M University.


Founding Principal Investigator at Altos labs, Authored True Age book


Post-Doctoral Researcher at Institute for Research on Cancer and Aging, Nice.


Senior Research Officer at Florey Institute of Neuroscience and Mental Health.

Company Representative

Founder of Gero and physicist in drug discovery land.


Associate Professor in Molecular Epidemiology at Karolinska Institutet.


Assistant Member at Oklahoma Medical Research Foundation.