Join the club for FREE to access the whole archive and other member benefits.

Salk scientists developed a new genome-editing tool tested on mice

New powerful tool is developed for targeting the non-coding areas of DNA

23-Aug-2019

Key points from article :

Novel technology could help treat many disorders caused by gene mutations.

SATI is enabling the team to target a broad range of mutations and cell types.

SATI works by inserting a normal copy of the problematic gene into the non-coding region of the DNA.

Scientists have focused on a mouse model of premature ageing caused by a mutation.

Next steps will be the improvements in the efficiency of SATI.

New genome-editing technology is described in Cell Research.

Mentioned in this article:

Click on resource name for more details.

Cell Research

Scientific journal covering cell biology.

Juan Carlos Izpisua Belmonte

Professor at the Salk Institute for Biological Studies, Director at San Diego Institute of Science, Altos Labs

Topics mentioned on this page:
Gene Therapy