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SIRT6, the longevity sirtuin proven to enhance healthy longevity


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SIRT6 also called “longevity sirtuin” has been making rather a name for itself.

SIRT6 is a protein vital for both normal base excision repair and double-strand break repair of DNA damage that can lead to genomic instability, contributing to aging. 

SIRT6 recruits PARP1, which acts as a ‘first responder’, detecting DNA damage and facilitating the choice of repair pathway.

The rodent trial uses a control group that is taking a placebo, and another group was given SIRT6Activator.

The mice that received SIRT6Activator had significantly lower frailty scores.

Longevity supplement company launched a SIRT6 activator product.

Vera Gorbunova, lead researcher told, “Epigenetic reprogramming is very powerful, SIRT6Activator is a safe way to repair the epigenome.”

The tests were carried out at the Gorbunova Aging Research Center at the University of Rochester.

SIRT6 Activator is a safe way to repair the genetic damages that may occur due to aging

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On a mission is to extend healthy lifespan for as many people as possible


Private research university that grants undergraduate and graduate degrees, including doctoral and professional degrees


Co-director Rochester Aging Research Center.