Join the club for FREE to access the whole archive and other member benefits.

Ageless Rx to investigate role of Rapamycin in human longevity

Set to launch Participatory Evaluation of Aging with Rapamycin for Longevity (PEARL) trial


Key points from article :

AgelessRX is going to investigate the efficacy and safety of rapamycin use to promote Longevity.

1,000 adults aged 50 years or more will receive the drug for up to a year.

Previous studies have shown positive results in mice models.

Middle-aged mice was treated with different dosing regimens of Rapamycin.

Significantly prolongation in survival occurred regardless of sex.

Prolonged treatment extended the lifespan of male but not of female mice.

Continuous exposure to rapamycin was more effective in female mice than intermittent regimens.

Findings of this study should be interpreted with caution since results are preliminary.

Translation from mice to human studies is the next challenge which Ageless Rx aims to overcome.

Research by University of Texas Health published in Aging Cell.

Mentioned in this article:

Click on resource name for more details.


Medical spa that offers select prescription therapies shown to safely prevent age related diseases.

Aging Cell

Scientific journal devoted to age related diseases

University of Texas Health

A campus in University of Texas that consists of five schools to train healthcare professionals

Topics mentioned on this page: