Key points from article :
Glucosamine supplementation results in about a 15% reduction in mortality.
Seen in this large-scale prospective cohort study of nearly half million UK adults.
Evaluated association between regular glucosamine supplement use and mortality from all causes.
This includes cardiovascular disease (CVD), cancer, respiratory, and digestive diseases.
Human, animal, and lab studies suggested its anti-inflammatory properties.
Done by inhibiting transcription factor NF-κB from translocating to the nucleus.
This reduces inflammation, and thus lowering related mortality.
An animal study also reported glucosamine could trigger mimic response of low carb diet.
This is by reducing glycolysis and increasing amino acid catabolism in mice.
Altogether, these explain linkage between glucosamine use and protective effect.
Researchers from Southern Medical University and other reputable universities.
Published in Annals of the Rheumatic Diseases.
