Mitochondria damage linked to diabetes cell failure
Lifespan.io (LEAF) - 11-Feb-2025Blocking stress response restored cell identity in mice, suggesting new treatment possibilities
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Diabetes is currently the 5th most common cause of death in the world.
5% of people (1 in 20) in the UK have diabetes.
Diabetes is the 7th leading cause of death in the US.
Around 1 in 8 people between 20 and 79 years old have their death attributed to diabetes.
The average life expectancy is reduced by:
More than 20 years (Type 1)
Up to 10 years (Type 2)
Blocking stress response restored cell identity in mice, suggesting new treatment possibilities
One in five adults now live with diabetes or pre-diabetes, prompting urgent calls for action
Approved uses are beneficial, but risks for off-label uses remain uncertain
Early trial results show promise for insulin production without immune suppression
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Associate Professor of Medicine, Harvard Medical School at Massachusetts General Hospital.
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