Key points from article :
Cells in intestinal tissue send signals via Wnt pathway and rouse intestinal epithelial cells.
Due to ageing, enzyme Notum blocks the supply of fresh cells to tissues.
So stem cells become unresponsive to Wnt signals.
Blocking Notum will resume Wnt pathway and rejuvenate tissue again.
Can combat age-related gastrointestinal conditions and reduce side effects of cancer therapy.
Study by University of Helsinki published in Nature.