Key points from article :
Nicotinamide adenine dinucleotide is a vital component of cellular function.
Decrease level of NAD+ is associated with aging and disease.
Involved in electron transfer and regulation of various biological pathways.
Actively destroyed by the membrane-bound NADase enzyme CD38.
Inflammaging may be driving the increased expression of CD38.
NAD+ boosting therapies, human trials now, are a near-future prospect.