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Why NAD+ Declines With Age

19-Mar-2018

Key points from article :

Nicotinamide adenine dinucleotide is a vital component of cellular function.

Decrease level of NAD+ is associated with aging and disease.

Involved in electron transfer and regulation of various biological pathways.

Actively destroyed by the membrane-bound NADase enzyme CD38.

Inflammaging may be driving the increased expression of CD38.

NAD+ boosting therapies, human trials now, are a near-future prospect.

Mentioned in this article:

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Harvard Medical School

Graduate medical school of Harvard University

Topics mentioned on this page:
Fountains of Youth