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Naked mole rats' secret to long life could be unlocked for humans


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University of Rochester researchers transferred a longevity gene from naked mole rats to mice, boosting health and extending their lifespan.

The gene for high molecular weight hyaluronic acid (HMW-HA) in naked mole rats boosts their cancer resistance.

The study showed that mice that had the naked mole rat version of the gene had a 4.4% increase in median lifespan.

These findings could lead to longer, healthier lives by advancing treatments for cancer and age-related diseases.

The researchers are currently conducting pre-clinical trials of molecules that slow down the degradation of HMW-HA.

Research led by Vera Gorbunova and Andrei Seluanov was published in Nature.

Scientists transfer the longevity gene to mice, extending their lifespan by 4.4%

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Andrei Seluanov

Associate Professor at University of Rochester


Scientific journal covering research from a variety of academic disciplines, mostly in science and technology

University of Rochester

Private research university that grants undergraduate and graduate degrees, including doctoral and professional degrees

Vera Gorbunova

Co-director Rochester Aging Research Center

Naked mole rats' secret to long life could be unlocked for humans