Key points from article :
NAD+ is essential for many cellular processes, including signaling and DNA repair.
Created from simple amino acids or in a more complex way via the intake of food.
Difficult to infuse cells directly with NAD+ as too large to pass through membrane.
In mice study rejuvenated muscle of 2-year-old mice to tissues of 4-month-old mice.
David Sinclair restore blood flow in old mice using NMN which converted into NAD+.
Now running a small-scale human trial on NMN.
NMN could be a useful stop-gap while waiting for more robust therapies to arrive.
The study was published in the Science journal.
