Ageing in mice - the systemic burden of senescent cells matters
Measuring the number of senescent cells in tissues is important in senescent cell related research.
Their differences could reflect different levels of genotoxic stress and responses to that stress.
Quantified senescent cells in wild type mice group and mice with accelerated ageing.
Surveyed multiple tissues for markers of senescent cell indices such as SASP in mice.
Cell amount correlates with health of the organism and maybe useful in predicting health span.
A collaborative study published in the journal Aging Cell.
Mentioned in this article:
Aging Cell - Scientific Journal devoted to age related diseases.