Key points from article :
Michael West presents at Ending Age-Related Diseases 2019
Nuclear transfer can reset telomeres.
Egg cells are like a cellular time machine.
Telomere lengthening possible with induced pluripotent stem cells.
Reprogramming can reverse multiple important markers of ageing.
Can it be done in a clinic?
Scientifical consensus previously said we would never understand how cells age.
Heart is able to regenerate all the way up birth.
Telomerase turned off within the first few weeks of foetal development.
Repression of regeneration coincides with switch to OXPHOS at the Embryonic-Fetal Transition (EFT).
Telomerase turns on in 90% of cancers.
Have been screening more molecules to see if any will turn telomerase back on.
