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Your organs and systems are ageing at different rates, new study finds

08-Mar-2022

Key points from article :

Researchers revealed the complexity that underlies the aging process.

Data obtained from 4000 volunteers on 403 features.

“Age-related changes could be detected in the 20s, we decided to focus on this age range,” - Brian Kennedy, co-corresponding author.

Nine clocks for cardiovascular, renal, liver, sex hormones, facial skin, metabolism/nutrition, immunological, fitness, & gut microbiome.

Cardiovascular age was largely explainable by the age.

Liver or renal age varied hugely even among people with the same chronological age.

Use of multiple clocks could show which component is driving the aging process.

A combined cardiovascular, liver and renal systems could predict mortality better than single measurement.

Significant environment impact on our bodies, which are harder to predict from purely biological data.

“Our approaches can improve understanding of aging and could be used some day in healthcare practice,” - Xun Xu, senior author.

Study by BGI and NUS published in Cell Reports.

Biological age differs from one organ to other, suggesting practical use of multiple clocks

Mentioned in this article:

Tap on icon for description, click on resource name for more details.

Company

Life sciences and genomics company in China

Academic

Prof of Biochemistry and Physiology at NUS. CSO Ponce De Leon Health.

Journal

Journal publishing research papers across a broad range of disciplines within the life sciences.

Academia

Asia’s leading university with a global approach in education, research and service.

Company Representative

Executive Director of BGI Group