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Direct oxidative stress on telomeres leads to faster cellular ageing

14-May-2019

Key points from article :

Sources that inflict oxidative stress on cells cause shortening of telomeres.

This is conclusive evidence that oxidative stress acting on telomeres can hasten cellular ageing.

Light activated molecules that can latch on to the telomeres were used to give dose-controlled oxidative stress.

Telomeres in cultured cancer cells shortened with each cell division despite repair efforts.

Prospect of interventions that protect telomeres in normal cells and target telomeres in cancer cells.

Research by University of Pittsburgh, published in the journal Molecular Cell.

Prevents uncontrolled cell division in cancer cells

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Molecular Cell

Journal that covers research on cell biology at the molecular level.

Patricia Opresko

Associate Professor in Department of Environmental and Occupational Health at the University of Pittsburgh

University of Pittsburgh

Public state-related research university