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Wearable bioreactor induced a limb regeneration


Key points from article :

Wearable bioreactor was attached to the wound site to deliver the progesterone locally for 24 hours.  

24 hour of exposure led to 9 months of changes in gene expression, innervation, and patterned growth. 

Device contains a silk protein-based hydrogel which is applied directly to the wound. 

Drug-device combination could be a new model for the regeneration of non-regenerative species. 

Results have published in Cell Reports. 

Research has done by Tufts University biologists and engineers.

Delivering progesterone to an amputation injury site can induce the regeneration of limbs

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Postdoctoral Researcher at Tufts University.


Journal publishing research papers across a broad range of disciplines within the life sciences.


Public Research university.