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New 'ageing clock' measures protein build-up to predict health and disease risk

Protein clumps hold potential for early disease detection, but more research is needed to develop a routine test

07-Jun-2024

Key points from article :

Proteins in our cells can clump together as we age, forming amyloids.

These protein clumps, especially from IDPs (intrinsically disordered proteins), are linked to age-related diseases.

Researchers propose a "protein aggregation clock" to measure a person's health and age.

This clock could help diagnose diseases earlier and identify people at higher risk.

It could also assess potential treatments for reducing protein aggregation to prevent or delay age-related diseases.

Protein clocks would complement existing DNA-based ageing clocks.

More research is needed to develop a protein aggregation clock into a diagnostic tool.

Research by Johannes Gutenberg University Mainz (JGU), published in Nature Cell Biology.

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Nature Cell Biology

Scientific journal covering research in cell biology.

Topics mentioned on this page:
Biological Age, Proteomics
New 'ageing clock' measures protein build-up to predict health and disease risk