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Interview with National Institute on Aging Scientific Director

Most hallmarks of aging only described in mice, so far, but Luigi Ferrucci is still optimistic


Key points from article :

Chief Editor of Nature Aging journal, Sebastien Thuault, interviews Luigi Ferrucci.

Defines aging as the ratio between damage accumulation and compensatory mechanisms.

Accumulation of damage occurs in the molecules that take care of the damage, and so slowly and progressively, this compensation becomes less effective.

Aging starts at conception.

Remembers being rebuffed for a treatment for frailty - "We cannot treat everybody."

Biological aging occurs before the development of a disease.

90% of the hallmarks of aging have only been described in mice.

Translation to the clinic will not occur without a common language and collaborations across disciplines.

There’s never been a more appropriate moment to dedicate oneself to older adults.

Thinks the amyloid hypothesis for AD is fading and people are struggling to find other hypotheses.

The COVID-19 pandemic further highlighted that race, socioeconomic status and access to health care are barriers to equal health for all.

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Luigi Ferrucci

Scientific Director at the National Institutes of Aging (NIA)

National Institute on Aging (NIA)

Conducting and supporting research on aging and the health and well-being of older people.

Topics mentioned on this page:
Ageing Research