Key points from article :
Ponce de Leon Health release results of a pilot consumer trial with its dietary supplement Rejuvant LifeTabs.
Claims it reduced the epigenetic age of participants by an average of 8.5 years.
PdL worked with Dr. Brian Kennedy when at the Buck Institute - now their chief scientific officer.
Identified generally recognized as safe (GRAS) compounds that could modulate a number of pathways linked to aging.
Rejuvant contains a proprietary form of calcium alpha-ketoglutarate.
Slows down rate of age-related DNA methylation and reduces inflammation caused by senescent cells.
17 customers took a TruAge test when starting Rejuvant, and again 4 to 6 months later.
TruAge Index measures DNA methylation.
Two-thirds of participants showed a statistically significant reduction in biological age.
Proprietary active ingredient LifeAKG increased lifespan and healthspan in mammalian models.
Randomized, double-blind, placebo-controlled clinical trial, to be conducted at Indiana University Medical Center later this year.
