Key points from article :
Hair follicle undergoes repetitive cyclic regeneration.
Aging phenotypes include irreversible hair loss, hair thinning and graying.
Wnt signaling promotes differentiation of melanocyte stem cell, exhaustion of which leads to hair graying during aging.
Wnt3a induces melanocyte stem cell differentiation in vivo and in vitro.
Demonstrated accelerated hair graying by increasing Wnt signaling.
Not known if reverse effect can be produced via suppression of this pathway in older animals.
The study was published in the Oncotarget journal.
