Genes vs. diet: what really drives longevity?
The Conversation (UK) - 17-Oct-2024New study finds calorie restriction aids longevity, but genetics may hold the ultimate key
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The only proven way of currently extending life expectancy in a variety of mammals is undernourishment (not malnourishment) but requires further study to see whether it has undesirable side effects.
Long lived species have less response to famine so, according to Aubrey de Grey, not likely to have a big impact in humans.
Laboratory mice primarily die from cancer, so any treatment that reduces cancer incidence is likely to have an impact on average lifespan even if not affecting the underlying ageing damage.
And when it comes to humans on a standard western diet (not that healthy), research is difficult as reducing calories may be just from normal (too much) to healthy levels. That doesn't necessarily mean reducing calorie intake further will be good for you.
New study finds calorie restriction aids longevity, but genetics may hold the ultimate key
A major study shows genetics and immunity are key to the lifespan benefits of calorie restriction
Energy expenditure, not just eating less, lead to 20% longer life in mice
Clearly, eating less may not be a straightforward path to slowing ageing
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Nonprofit organization focused on extending human longevity through calorie restriction
Science Writer at SENS Research Foundation, Ex-Board Member of the Calorie Restriction Society
A revolutionary diet that provides the body with fewer calories than is traditionally required written by Paul McGlothin
A book written by Brian M. Delaney and Lisa Walford that explains in practical terms the concept of calorie restriction
Explains NAD+ synthesis is circadian, and how SIRT1 is critical in ISCs - 2016 Roy Walford lecture