Calorie Restriction

The only proven way of currently extending life expectancy in a variety of mammals is undernourishment (not malnourishment) but requires further study to see whether it has undesirable side effects.

Long lived species have less response to famine so, according to Aubrey de Grey, not likely to have a big impact in humans.

Resources

More info: CR Society International

Recent News

Low-calorie diet prevents age-related molecular changes

Medical Xpress - 25-May-2018

Epigenetic changes strongly influence the way the genes operate.

CR Leads to Longer Life but Less Grey Matter

Genetic Engineering & Biotechnology News (GEN) - 05-Apr-2018

New study shows caloric restriction in lemurs extended lifespan up to 50%.

Reduced-?calorie diet slows ageing in people

Nature - 22-Mar-2018

CALERIE multi-centre trial tested 200 healthy, non-obese adults over 2 years.