The only proven way of currently extending life expectancy in a variety of mammals is undernourishment (not malnourishment) but requires further study to see whether it has undesirable side effects.
Long lived species have less response to famine so, according to Aubrey de Grey, not likely to have a big impact in humans.
Leonard P. Guarente on NAD, Sirtuins and Aging - Explains NAD+ synthesis is circadian, and how SIRT1 is critical in ISCs - 2016 Roy Walford lectureMore Calorie Restriction resources
Double-strand break DNA repair improved in calorie restriction mice
Life Extension Advocacy Foundation (LEAF) - 10-Sep-2020
Helps us to understand the mechanism behind CR - and that it has an effect within weeksRead more...
Benefits of caloric restriction in intestinal stem cells
Lifespan.io - 05-Aug-2020
One should still consume adequate nutrition while reducing calorie intakeRead more...
Looking young means you are probably ageing slower
CR VITALITY - 30-Jun-2020
Good genes combined with healthy lifestyle choices can truly make you look youngerRead more...