The only proven way of currently extending life expectancy in a variety of mammals is undernourishment (not malnourishment) but requires further study to see whether it has undesirable side effects.
Long lived species have less response to famine so, according to Aubrey de Grey, not likely to have a big impact in humans.
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Nonprofit organization focused on extending human longevity through calorie restriction
Book about food and dieting by James W. Clement.
Explains NAD+ synthesis is circadian, and how SIRT1 is critical in ISCs - 2016 Roy Walford lecture
New study responsible for the metabolic benefits of a Calorie restriction diet.
University of Wisconsin-Madison - 18-Oct-2021
Fasting alone recapitulates the effects of Calorie restrictionRead more...
Calorie restriction slows age-related stem cell exhaustion, improving overall health
Lifespan.io (LEAF) - 29-Sep-2021
Many studies underlined beneficial effects of calorie restriction in various tissues of miceRead more...
Study finds multiple health benefits from time restricted eating (TRE)
EurekAlert! - 17-Aug-2021
Strong protection against fatty liver disease seen in mice regardless of age and sexRead more...
Long-term caloric restriction prevents age-related adiposity in aged mice
Lifespan.io (LEAF) - 02-Jul-2021
Targeting SA-T cells: A promising intervention to control age-related chronic diseasesRead more...
Eating less than 800 calories a day favoured weight loss via hungry pathogens
ScienceAlert - 27-Jun-2021
Long-term safety of the diet is questionable as it alters the healthy gut microbiomeRead more...