The only proven way of currently extending life expectancy in a variety of mammals is undernourishment (not malnourishment) but requires further study to see whether it has undesirable side effects.
Long lived species have less response to famine so, according to Aubrey de Grey, not likely to have a big impact in humans.
Autophagy may be the reason behind benefits of calorie restriction
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Calorie restriction can restore myelin on demyelinated nerves
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Growth Differentiation Factor 11 - beneficial effects in mouse model
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