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Calorie Restriction

The only proven way of currently extending life expectancy in a variety of mammals is undernourishment (not malnourishment) but requires further study to see whether it has undesirable side effects.

Long lived species have less response to famine so, according to Aubrey de Grey, not likely to have a big impact in humans.

Laboratory mice primarily die from cancer, so any treatment that reduces cancer incidence is likely to have an impact on average lifespan even if not affecting the underlying ageing damage.


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CR Society International

Nonprofit organization focused on extending human longevity through calorie restriction

Fasting & Aging: Why Women are Different


Oxford Longevity Project webinar about fasting and difference between men and women with Dr. Stephanie Estima and Abhinav Diwan

Michael Rae

Science Writer at SENS Research Foundation, Ex-Board Member of the Calorie Restriction Society

The Longevity Diet


A book written by Brian M. Delaney and Lisa Walford that explains in practical terms the concept of calorie restriction

Dr. Satchin Panda on Practical Implementation of Time-Restricted Eating & Shift Work Strategies

2 hour interview with Dr. Rhonda Patrick (FoundMyFitness) on YouTube

Leonard P. Guarente on NAD, Sirtuins and Aging

Explains NAD+ synthesis is circadian, and how SIRT1 is critical in ISCs - 2016 Roy Walford lecture

More Calorie Restriction resources

Recent News

University of Alabama at Birmingham looking for IF and CR participants for new study

University of Alabama at Birmingham (UAB) - 10-Oct-2022

Will look at whether health and ageing improves with calorie restriction or intermittent fasting


Low-calorie diet during active period of the cycle increased lifespan in mice

UT Southwestern Medical Center - 05-May-2022

Triple the effect seen over simply restricting calorie intake


Limiting calories rewires immuno-metabolic function for longer healthspan in humans

GEN News - 14-Feb-2022

Protein produced by macrophages was identified as a key player of calorie restriction


Exercise paired with intermittent fasting is the best way for fat loss

University of Toronto - 07-Feb-2022

Experts share the science, benefits, best timings, and other tips of intermittent fasting


Feeding dogs once daily might improve health and cognitive function

Newsweek - 16-Nov-2021

This is another indicator that time restricted eating (TRE) has benefits in mammals

More Calorie Restriction News