Calorie Restriction

The only proven way of currently extending life expectancy in a variety of mammals is undernourishment (not malnourishment) but requires further study to see whether it has undesirable side effects.

Long lived species have less response to famine so, according to Aubrey de Grey, not likely to have a big impact in humans.


Video Leonard P. Guarente on NAD, Sirtuins and Aging - Explains NAD+ synthesis is circadian, and how SIRT1 is critical in ISCs - 2016 Roy Walford lecture

Academic Michael Rae

Book The CR Way: Using the Secrets of Calorie Restriction for a Longer, Healthier Life - Amazon

Book The Longevity Diet - Amazon

Institute CR Society International

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Recent News

Looking young means you are probably ageing slower

CR VITALITY - 30-Jun-2020

Good genes combined with healthy lifestyle choices can truly make you look younger


Calorie restriction rejuvenates 'brain immune cells' in mice

Fight Aging! - 27-May-2020

Still one of the most reliable interventions when improving long-term health


Dawn til dusk fasting improves blood biomarkers

Life Extension Advocacy Foundation (LEAF) - 08-Apr-2020

Small study (14 participants) with strict participation requirements, but interesting biomarker results

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