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Calorie Restriction

The only proven way of currently extending life expectancy in a variety of mammals is undernourishment (not malnourishment) but requires further study to see whether it has undesirable side effects.

Long lived species have less response to famine so, according to Aubrey de Grey, not likely to have a big impact in humans.

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Recent News

Food odour nullifies lifespan benefits of dietary restriction in nematodes

Lifespan.io (LEAF) - 29-Apr-2021

You may have to avoid smelling, not just eating, food for CR to be effective

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A low-calorie diet maintains youthful gut state & improves lifespan

Fight Aging! - 24-Mar-2021

Calorie restriction prevents age-related changes to the gut microbiome in mice

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Rapamycin might not be an alternative for calorie restriction

Lifespan.io (LEAF) - 27-Jan-2021

Failed to mimic dietary restriction pathways on extending lifespan in progeroid mice

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