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3D printed heart like organoid can contract spontaneously and synchronously

This organoid with chambers can fit into a mouse's belly

15-Jul-2020

Key points from article :

Scientists 3D printed a functioning centimetre-scale human heart pump in the lab.

Used a combination of extracellular matrix protein ink and stem cells to 3D print the heart.

Expanded stem cells in to high density structures and then differentiated into heart muscle cells.

Cells organized to make a 1.5 cm long closed sac with a fluid inlet and fluid outlet.

Worked together contracting spontaneously and synchronously.

Plans to subject it to disease and damage in order to study heart diseases.

Research by University of Minnesota published in the journal Circulation Research.

Mentioned in this article:

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Brenda M. Ogle

Professor and Head of the Department of Biomedical Engineering at University of Minnesota

Circulation Research

Medical journal providing information about cardiovascular system.

Molly E. Kupfer

Clinical Product Risk Specialist at Boston Scientific

University of Minnesota

Public Research university.

Wei-Han Lin

Biomedical engineering Ph.D. student at University of Minnesota

Topics mentioned on this page:
Regenerative Medicine, 3D Printing (Healthcare)