Key points from article :
iPSCs treatments have been slowed by concerns that these cells are prone to increased numbers of genetic mutations.
New research suggests that iPSCs do not develop more mutations than cells that are duplicated by subcloning.
Finding suggests that most mutations in iPSCs are not generated during the reprogramming but are rare genetic variants inherited from the parent skin cells.
The study was published in the Proceedings of the National Academy of Sciences.
