Key points from article :
CR changes near everything in the operation of metabolism and slows near every measure of aging making it difficult to figure out chains of cause and effect.
Does not repair of damage.
Review of recent studies includes:
Mitochondrial activity and ROS production are modulated by CR
Importance of membrane lipid composition on the CR effect
Antioxidant activities in ageing and CR
AMP-dependent protein kinase (AMPK)
Sirtuins
… and many more.