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Fountains of Youth

Here is a round up of the current contenders for slowing or reducing aging. As research continues, and if/when they make real advancements in human trials (or at least human cells) I'll split them into their own pages with more analysis.

Metformin

Diabetics who are on metformin actually seem to be living longer than nondiabetics who are not on it - Bill Gifford

David Sinclair has said he is taking it - but skips the pill on days that he exercises.

Radiation Hormesis

Non-sanctioned therapy used by athritis sufferers.

The Therapeutic use of Radon: A Biomedical Treatment in Europe; An “Alternative” Remedy in the United States - National Center for Biotechnology Information - 23-Sep-2006
Discusses the decision-making process involved in using radon, and compare the Montana radon health mine facilities with selected radon mines and spas in Europe.

Rapamycin (aka sirolimus)

A chemical produced by bacteria that has been shown to have immunosuppressive and antiproliferative properties. It is currently used in the prevention of transplant rejection and as a coronary stent coating, and is also being tested for certain cancers.

Fountains of Youth News

Metformin misses the mark in PAD

Metformin misses the mark in PAD

Healio - 14-Nov-2025

Walking performance in non-diabetic PAD patients remained unchanged despite metformin treatment

UK’s illegal teeth-whitening trade exposed by BBC investigation

UK’s illegal teeth-whitening trade exposed by BBC investigation

BBC - 29-Oct-2025

BBC finds untrained beauticians using dangerous high-strength bleach, putting consumers at risk

The high price of staying young: inside the world of longevity clinics

The high price of staying young: inside the world of longevity clinics

Aging - 13-Oct-2025

Private anti-aging clinics promise healthspan gains but risk science credibility

Rapamycin tops NIH review of anti-aging drugs

Rapamycin tops NIH review of anti-aging drugs

UT Health San Antonio - 28-Aug-2025

Rapamycin extended mouse lifespan by up to 28%, even when given in mid or late life, review finds

More Fountains of Youth News

Fountains of Youth Resources

Click on resource name for more details.

Doctor Mortgaged House For $150k To Prove Longevity Drug Works

Optispan podcast episode - Brad Stanfield discusses his journey from GP to longevity leader

Two Promising Drugs for Alzheimer’s & Aging with Jon Berner (Science Backed)

Optispan podcast episode - Lithium and Rapamycin: new hope for Alzheimer’s

Longevity Conference Attendees Hospitalized After Using Peptides?

Optispan podcast episode - Longevity Conference Turns Risky After Peptide Use?

Longevity Genes, Blood Biomarkers of Aging, & Targeting Aging with Metformin with Dr. Nir Barzilai

Longevity by design Podcast Episode - Dr. Nir Barzilai on longevity genes, aging biomarkers, and metformin

Longevity Lie: Doctor Reveals Why Anti-Aging Supplements Don’t Work

Optispan Podcast Episode - Dr. Alex and Dr. Jan explain why most anti-aging supplements fail to deliver results

Doctor Reveals: The Dark Side Of The Longevity Industry

Optispan podcast episode - Matt explores the hidden challenges within the longevity industry

More Fountains of Youth resources

Fountains of Youth Blog Posts

Choosing supplements - why all supplements are not the same
31-Jul-2023

Choosing supplements - why all supplements are not the same

When selecting a supplement, price is not the sole determining factor

More Fountains of Youth blog posts
Topics covered in this page:
Fountains of Youth, Metformin, Rapamycin, Snake Oil