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Biodegradable heart valves and vessels tested in pre-clinical trials

07-Jan-2021

Key points from article :

Replacement stents and heart valves made from biodegradable materials can be a permanent solution.

Biodegradable plastic heart valves and blood vessels are accepted by the body and transformed into living tissue in pre-clinical trials.

“This new stent triggers the body to heal the damaged artery from the inside, while the stent structure itself only stays temporarily in the body.” - Carlijin Bouten, lead author.

Small-diameter vascular implant made from a biodegradable electrospun polymer can be inserted using a minimally invasive approach.

Cell-free biodegradable heart valves promote colonization of host cells in the valve structure, tissue formation, and remodeling.

Implanted valves were capable of sustaining valve functionality for up to 1 year.

The plastic implant was degraded and replaced by new tissue that was regenerated by the body itself.

Research by the Eindhoven University of Technology published in the journal JACC: Basic to Translational Science.

Could eliminate the risks of traditional non-degradable permanent prostheses

Mentioned in this article:

Academic

Professor at Department of Biomedical Engineering, Eindhoven University of Technology

Academia

Technical university in the Netherlands, operating in English.

Journal

Scientific Journal providing information about cardiovascular diesases.