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Escape from senescence boosts tumour growth

20-Dec-2017

Key points from article :

Senescence is usually thought to be irreversible.

Many anti-cancer therapies cause cancer-cell senescence.

Cells have a boosted capacity to drive tumour growth if they exit senescence.

cellular signalling pathways activated during chemotherapy-induced senescence are similar to the gene-expression patterns observed in stem cells.

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Maja Milanovic

Study Director in division of Oncology/Immunology at preclinics

Topics mentioned on this page:
Senescent Cells