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Fasting-mimicking diet reduces disease risk and slows biological ageing in humans

Fasting improved health markers like insulin resistance and liver fat

20-Feb-2024

Key points from article :

Researchers from the USC Leonard Davis School of Gerontology conducted a study to investigate the effects of a fasting-mimicking diet (FMD) on ageing and disease risk factors in humans.

The study involved 100 participants completing periodic 5-day cycles of the FMD, which is high in healthy fats and low in calories, mimicking the effects of fasting.

Researchers found that the FMD cycles reduced insulin resistance (a diabetes risk factor) and liver fat.

The diet also favorably influenced markers of immune system ageing, making the immune system appear more youthful.

Analysis of study results revealed that participants had, on average, a 2.5-year reduction in their biological age, a measure of overall cellular health.

This study, published in Nature Communications, provides strong evidence that the FMD can potentially reduce disease risk and promote healthier ageing without requiring major lifestyle changes.

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Nature Communications

Journal covering all topics in physics, chemistry, and biology

USC Leonard Davis School of Gerontology

University department in Los Angeles, California.

Topics mentioned on this page:
Intermittent Fasting (IF), Biological Age
Fasting-mimicking diet reduces disease risk and slows biological ageing in humans