Biological age measured using popular epigenetic clocks vary by 3 years during the day

Live Forever Club - 23-Apr-2024

Schedule blood tests at the same time of day when tracking biological age over time

Some everyday medications could lengthen life, while others like opioids might pose risks

Live Forever Club - 22-Apr-2024

Surprisingly, metformin does not reduce death risk

Stem cells could potentially rejuvenate the thymus gland in older individuals

Live Forever Club - 21-Apr-2024

Potential tool in boosting immune function and combating the effects of ageing

Body's repair system falters with age as stem cells lose their regenerative power

Live Forever Club - 12-Apr-2024

Machine learning reveals widespread decline in stem cell potency with age

Antibody treatment rejuvenates aged immune systems in mice

Science - 04-Apr-2024

Researchers improved immune response to new infections and reduced overall inflammation

Scientists found cholesterol eating bacteria in the gut

Broad Institute of MIT and Harvard - 02-Apr-2024

Some bacteria may hold key to lower cholesterol and heart disease risk

Somatic mutations: Do these DNA changes hold the secrets to longevity?

Live Forever Club - 31-Mar-2024

The gradual buildup of DNA mutations may hold clues on how to combat age-related diseases

Novel antibody therapy rejuvenates aging immune systems in mice

New Scientist - 27-Mar-2024

Potential treatment approach to boost immunity and fight disease in older adults

Ani Biome receives funding to personalise gut health treatments for longevity

Longevity Technology - 26-Mar-2024

Company will use machine learning and gut health science to create custom solutions

Lifespan.io interviews David Sinclair about his Information Theory of Aging and much more

Lifespan.io (LEAF) - 22-Mar-2024

Backup code: ageing cells from epigenetic changes could potentially be reset to a youthful state

UCL study reveals cancer risk associated with vaping-induced DNA damage

Sky News - 20-Mar-2024

Study finds concerning similarities in DNA damage between vapers and smokers

Extending quality life years: insights from the Global Healthspan Summit 2023

Live Forever Club - 16-Mar-2024

Event focused on extending quality life years through scientific innovation

UK study finds 14 prescription meds possibly linked to longer life

Lifespan.io (LEAF) - 15-Mar-2024

Viagra, cholesterol meds & estrogen replacements linked to longevity, but further research needed

Genomenon develops AI-powered tool to uncover links between genes and diseases

Inside Precision Medicine - 15-Mar-2024

This new technology could improve the accuracy of genetic testing

Transplanted cells age at different rates depending on the host's age

Live Forever Club - 05-Mar-2024

Bodies of younger people could potentially rejuvenate older transplanted cells

Cell malfunctions can cause information leakage and trigger inflammation

University of Virginia School of Medicine - 05-Mar-2024

The discovery may improve inflammation treatment and anti-ageing interventions

Argentine scientists explore young blood's anti-ageing effects in rats

Live Forever Club - 04-Mar-2024

The old rats that got young blood lived longer and looked healthier

Antibiotics for blindness: Gut bacteria linked to inherited eye diseases

Independent - 26-Feb-2024

CRB1 gene mutation weakens gut barrier, allowing bacteria to invade eyes

A protein called APOB, key to blood fat control, could influence your lifespan

Live Forever Club - 25-Feb-2024

Lowering APOB could potentially delay age-related diseases like Alzheimer's

Gut bacteria and blood molecules offer clues to why grip strength weakens with age

Live Forever Club - 21-Feb-2024

Research opens doors for future interventions to prevent muscle loss

Harvard scientists created a tool that predicts how old your cells really are

Harvard University - 16-Feb-2024

This could lead to more accurate testing of anti-ageing interventions

New research links DNA damage to incomplete gene transcription in aging

Lifespan.io (LEAF) - 15-Feb-2024

DNA damage accumulated with age worsens gene expression, affecting lifespan-determining pathways

Skincare myths debunked: What products actually work for ageing skin?

Live Forever Club - 14-Feb-2024

To name a few, moisturizers with acidic pH and emollients with active ingredients can help

Scientists grew tiny heart-like tissues with CVD in a lab dish, using stem cells

University of East London (UEL) - 13-Feb-2024

Research has the potential to revolutionise heart disease treatment in older adults

Northwestern University launches the Human Longevity Laboratory to fight ageing

Northwestern University - 12-Feb-2024

Researchers will work finding ways to live healthier and longer

Mouse models get a major boost as UK funds research on dementia and ageing

UK Research and Innovation (UKRI) - 12-Feb-2024

This collaboration aims to unlock the secrets of ageing and develop new therapies

Some gut viruses may help you deal with stress by fighting harmful bacteria

The Guardian - 06-Feb-2024

Under stress, the composition of gut viruses and bacteria changed in mice

Scientists found a way to make old cells young again in a lab

Live Forever Club - 04-Feb-2024

They used special proteins to erase "marks" on DNA that build up with age

Eating fermented foods like kimchi or yogurt might make you think clearer

Medical News Today - 02-Feb-2024

Adding fermented foods to your diet is a safe way to support your gut

Space travel throws a curveball at astronauts' guts, challenging their health

Earth.com - 02-Feb-2024

Understanding the adaptation is crucial for protecting them on long missions

Anti-inflammatory benefits: fasting found to reduce risk of many diseases

University of Cambridge - 30-Jan-2024

Calorie restriction silences the NLRP3 inflammasome, a key driver of inflammation

Scientists found a "nose and gut trick" that could help us live longer

Live Forever Club - 28-Jan-2024

It helped mice live longer, look healthier, and have sharper minds

AI and quantum computing join forces to crack the code of life

EurekAlert! - 26-Jan-2024

This "physics-guided AI" approach promises deeper insights than current methods

The Hevolution Foundation's report proposes a radical shift in healthcare

Live Forever Club - 23-Jan-2024

Report suggests that our focus needs to move from lifespan to healthspan

Turns out, women have a secret weapon in the longevity game: their DNA!

Live Forever Club - 21-Jan-2024

Women have an advantage in longevity genes, especially those related to immunity

Simple at-home fingerprick test reveals thousands of health insights

Stanford University School of Medicine - 19-Jan-2024

Reading metabolic and immune responses, blood test paves way for early diagnosis & personalized medicine

Once helpful immune alarm bells, inflammasomes now fuel chronic diseases

Live Forever Club - 18-Jan-2024

Researchers are developing new treatments to turn down the inflammatory response

Halia Therapeutics' NLRP3 inhibitor shows promise in tackling chronic inflammation

Longevity Technology - 11-Jan-2024

Shown promising results in preclinical studies and early clinical trials

Skin microbiome diversity is linked to wrinkles and hydration

University of California, San Diego (UCSD) - 11-Jan-2024

The findings pave the way for personalised skincare approaches

Ageing may be driven by disruptions in electrical signals between cells

Live Forever Club - 05-Jan-2024

Bioelectric signals could even promote tissue regeneration

Cambridge scientists are making significant strides in understanding ageing

Cambridge Independent - 05-Jan-2024

Promising leads for potential anti-ageing interventions in the next decade

Epigenetic remodelling startup 'Moonwalks' out with $57M to develop targeted therapies

Longevity Technology - 04-Jan-2024

This, they claim, is safer and more precise than traditional gene editing methods

Activating SIRT6, a DNA repair protein, reduces damage in ageing cells

Live Forever Club - 01-Jan-2024

SIRT6 activation may be a potential therapeutic target for osteoarthritis

A cellular protein called HKDC1 tidies up mitochondria and lysosomes

Interesting Engineering - 01-Jan-2024

This discovery paves the way for potential anti-ageing therapies

Ageing may not be just wear and tear, but a programmed continuation of development

Live Forever Club - 31-Dec-2023

Methylation patterns, measured by epigenetic clocks, offer novel insights

Josh Mitteldorf's new view of ageing shows body's fight for life

Live Forever Club - 31-Dec-2023

Study reveals two sides to ageing: a programmed decline and a desperate defense

Our sleep cycles and gut bacteria influence the brain's protective barrier

Live Forever Club - 30-Dec-2023

Interplay between these systems suggests potential for targeted interventions

El País interviews Altos Labs’ principal investigator Pura Muñoz Cánoves

El País - 27-Dec-2023

Altos labs with a $3-billion budget pave the way for reversing aging and extending healthy lifespan

LEV Foundation announces plan for second Robust Mouse Rejuvenation study (RMR2)

Live Forever Club - 22-Dec-2023

Will look at combinations of partial cellular reprogramming, mesenchymal stem cells, serum albumin and deuterated fatty acids

Cambridge researchers continuously explore novel approaches to improve healthspan

University of Cambridge - 20-Dec-2023

Quest for people to live healthily for as long as possible will inevitably result in longer lives

Antioxidants and seasickness meds show promise in extending life in male mice

Live Forever Club - 11-Dec-2023

The gender-specific effects observed underscore the complexity of ageing

Our genes push for early babies, but at the cost of living shorter lives

University of Michigan - 08-Dec-2023

But don't stress, modern factors like healthcare and lifestyle have a bigger impact than genes

SIRT2 overexpression does not significantly impact lifespan in mice

Live Forever Club - 05-Dec-2023

Study suggests a more nuanced role of this protein in the ageing

The reign of dinosaurs may have shaped how humans and other mammals age

Live Forever Club - 05-Dec-2023

Dinosaur-era pressures may have led to the loss of longevity genes

XPRIZE Launches a $101 Million Healthspan Competition

Live Forever Club - 29-Nov-2023

10 years of functional age-reversal in 65-80 year olds within the next 7 years... bring it on!!!

Gene regulation shifts with age, especially in species with shorter lifespans

Live Forever Club - 28-Nov-2023

CpG density may play a role in moderating the epigenetic drift

A fatty acid in beef and milk could be used to treat cancer

New Scientist - 22-Nov-2023

The acid eliminates tumours by activating immune cells to combat cancerous cells

C. elegans: A tiny worm that can help scientists understand how ageing works

Live Forever Club - 20-Nov-2023

The research could lead to new ways to slow down ageing in humans

Immune Resilience: a blueprint of your immune system that unveils the secrets of longevity

Big Think - 19-Nov-2023

Science behind your body's ability to live longer, resist infections and survive diseases

Forward therapeutics secures $50m to develop next-gen small molecule immune therapies

Longevity Technology - 09-Nov-2023

Company's pipeline targets inflammation, promote healing, and restore quality of life

New mice with human-like telomeres could help us fight ageing and cancer

The Jerusalem Post - 30-Oct-2023

Model could be used to study the role of telomere length in several diseases

Frontier Bio's lab-grown blood vessel tech revolutionizes medical device testing

3DPrint.com - 24-Oct-2023

Promises a future without animal testing and the need for organ donors

Unravelling the complexities of aging: A comprehensive database of aging factors

Live Forever Club - 23-Oct-2023

A deep dive into the AgingReG curated database of aging regulatory relationships in humans

UC Davis researchers uncover a gene linked to longevity in Golden Retrievers

UC Davis - 19-Oct-2023

HER4 gene types added approximately 2 years to their lifespan

Gut microbes linked to the risk of Parkinson’s and Alzheimer’s diseases

University of Massachusetts Lowell (UMass Lowell) - 19-Oct-2023

Gut-brain connection opens doors for early detection and treatment of brain diseases

Gut bacteria linked to Alzheimer's disease in groundbreaking study

King's College London - 17-Oct-2023

Research findings may lead to new treatments for the most common cause of dementia

New brain atlas reveals thousands of previously unknown cell types

New Scientist - 12-Oct-2023

Could lead to new insights into neurological and mental health conditions

CT scans of thymus may reveal immunological ageing

Medical Xpress - 12-Oct-2023

Researchers find link between thymus appearance and lifestyle factors, immune cell regeneration

Genetic profiling conducted by the mexico city prospective study highlights the value of genetic studies in diverse populations

Oxford Population Health - 11-Oct-2023

Study reveals new insights into obesity, diabetes, and genetic diversity

Largest centenarian blood study identifies key factors for long life

Independent - 10-Oct-2023

Lower levels of glucose, creatinine, and uric acid linked to increased longevity

Why some people find it easier to be a vegetarian than others

New Scientist - 04-Oct-2023

Three gene variants more prevalent in vegetarians, impacting dietary choices

Buck Institute and Phenome Health team up to advance scientific wellness

Buck Institute - 27-Sep-2023

Collaboration of data and discovery to extend healthspan for everyone

Lifespan.io reports back from Aging Research and Drug Discovery Meeting (ARDD 2023)

Lifespan.io (LEAF) - 26-Sep-2023

Key points from Arkadi Mazin's summary of 5 days of talks by geroscientists and biotech leaders

The Chan Zuckerberg Initiative to launch AI supercomputer for decoding biology

GEN News - 22-Sep-2023

New AI technologies promise to accelerate scientific discoveries and cure diseases by the end of the century

New AI tool predicts genetic mutations that could cause disease

The Guardian - 19-Sep-2023

AlphaMissense is a game-changer in genetic research for human health

Rejuve.Bio combines AI with fruit fly genetics to unlock the secrets of long life

Longevity Technology - 24-Aug-2023

Novel approach to identify ageing targets and fight age-related diseases

Naked mole rats' secret to long life could be unlocked for humans

University of Rochester - 23-Aug-2023

Scientists transfer the longevity gene to mice, extending their lifespan by 4.4%

Human cell's memory erased to resemble embryonic stem cells

EurekAlert! - 16-Aug-2023

New reprogramming method addresses epigenetic challenges & sets a standard for cell therapy research

Human heart on a microchip: A revolutionary new tool for medical research

Methuselah Foundation - 14-Aug-2023

Organ on a chip may be more successful than mice models in translating science to the clinic

Epigenetic insights: developmental changes in DNA linked to lifespan in mammals

EurekAlert! - 10-Aug-2023

Universal clock based on methylation profiles to accurately predict age in all mammalian species

New, publicly available "unknome" database for poorly studied proteins

New Scientist - 08-Aug-2023

Many neglected proteins/genes have essential function, finding out may accelerate future research

Signalling pathways in aged cells found to impair the ability to repair and regenerate muscle cells

Independent - 07-Aug-2023

Study results offer insights on future drug discovery for disease related to muscle ageing

Epiterna receives 10m euros to extend lifespans of pets and people

Sifted - 01-Aug-2023

Planning to test its therapies in dogs next year, with human treatments expected in the near future

If we can fix the bugs in human software, people could live to be 20,000 years old

Scientific American - 31-Jul-2023

Bill Gifford interviews João Pedro de Magalhães, professor of molecular biogerontology at the University of Birmingham

Intermittent fasting may help you lose weight and fight infections

New Scientist - 28-Jul-2023

T cells effectively fight pathogens using energy fuel as ketones, which are typically produced in fasting

Young blood slows down ageing process of older mice

New Scientist - 26-Jul-2023

Infusion of youthful blood increased lifespan by 5% and improved age-related gene alterations

Superior killer T-cells hold promise in remission and clearance of cancer

Cardiff University - 24-Jul-2023

Multipronged T-cells recognize multiple target proteins and attack cancer in many ways

Your genes determine your food cravings and eating habits

New Scientist - 22-Jul-2023

Identifying genetic preferences may hold the key to personalized nutrition and healthy eating

System Age epigenetic clock captured different patterns of ageing

Lifespan.io (LEAF) - 21-Jul-2023

Novel method for precise estimation of biological age and disease risks with a single blood sample

Automating genetics research: A robotic system for handling C. elegans (with video)

Phys.org - 06-Jul-2023

WormPicker takes on time-consuming tasks including inspection, movement between petri dishes and genetic crossing

Hunter-gatherer diet unveils incredible gut microbiome diversity

New Scientist - 21-Jun-2023

A study of Tanzania's Hadza people reveals over a thousand new gut microorganism species

Reason reports back from Age-Related Disease Therapeutics Summit 2023

Fight Aging! - 16-Jun-2023

Many people believe lots of clinical trials of novel therapeutics targeting mechanisms of aging will start up in the next few years

The bowhead whale's secret to living over 200 years: Remarkable DNA repair mechanisms

Live Forever Club - 30-May-2023

Exceptional longevity and resistance to cancer holds potential implications for human health and ageing

Proprietary GHK-Cu formulation by Yuvan Research clinically proven to increase skin collagen density

Live Forever Club - 29-May-2023

Epigenetic breakthrough offers hope for anti-aging therapies, harnessing the power of naturally occurring peptide

Hevolution Foundation allocates over $20 Million to promote aging research through HF-AGE grant program

Live Forever Club - 23-May-2023

Nine innovative projects, spread over seven US institutions, set to receive funding

Longevity Med Summit - Best of the Rest

Live Forever Club - 19-May-2023

Key points from more of the excellent speakers at the summit

Gut instinct: Toddler microbiota linked to future obesity risk

The Guardian - 19-May-2023

Better understanding of composition and changes of gut microbiome could lead to potential interventions

Summary of Fabrizio d’Adda di Fagagna presentation at Longevity Med Summit

Live Forever Club - 18-May-2023

Telomeres become sinks of irreparable damage - antisense oligonucleotides could potentially provide a fix

Summary of Daniel E. Martin-Herranz presentation at Longevity Med Summit

Live Forever Club - 18-May-2023

Building a saliva-based epigenetic biomarker for systemic chronic inflammation (SCI)

Summary of Aubrey de Grey presentation at Longevity Med Summit

Live Forever Club - 16-May-2023

A quick introduction to the preventative maintenance approach, LEV Foundation and Robust Mouse Rejuvenation

TechCrunch interviews founders of NewLimit after it received another $40m of funding

TechCrunch - 16-May-2023

Reprogramming the epigenetics of a cell could reverse a significant amount of the functional decline that we see with age

Summary of Max Unfried presentation at Longevity Med Summit

Live Forever Club - 12-May-2023

VitaDAO has already funded 17 projects - including research areas not supported by traditional government agencies

Summary of Gordan Lauc presentation at Longevity Med Summit

Live Forever Club - 11-May-2023

Glycans are the most neglected molecules of cellular communication

Pangenome: a new chapter in human DNA mapping embracing global diversity

BBC - 10-May-2023

Updated DNA map opens doors for more inclusive and effective medical treatments

VitaDAO provides $50,000 funding for ImmuneAGE Bio to accelerate its immune rejuvenation research

Longevity Technology - 10-May-2023

Will use its drug discovery platform to further development of lead compound, IA101

Unraveling the mysteries of aging: Epigenetic damage and the limits of cellular repair

Live Forever Club - 09-May-2023

Novel theory of biological systemic ageing suggests epigenetic ageing is inevitable

Pioneering longevity researcher joins SIRTLab to accelerate aging interventions

Longevity Technology - 09-May-2023

Nir Barzilai brings his expertise to boost the company's mission to extend healthspan by targeting age-related diseases

Live Forever Club becomes latest member of International Longevity Alliance (ILA)

Live Forever Club - 03-May-2023

Organisations share a common mission of healthy longevity for all through scientific research

Gut bacteria may have little or no impact on risk of chronic diseases or longevity

The Conversation (UK) - 02-May-2023

Further studies required to better characterize the association between gut microbiota and its metabolites

Poop pill: FDA approves first microbiota capsule to fight gut infections

AP News - 26-Apr-2023

Oral formulation offers a simpler way to restore gut balance & combat recurrent C.diff infections

Nuffield Council on Bioethics publishes its "The future of ageing" report

Nuffield Council on Bioethics - 25-Apr-2023

The report sets out an ethical framework and recommendations for research and innovation related to ageing

Maximon Longevity Prize 2023: Awarding Innovative Research Projects that Extend Human Lifespan

Maximon - 20-Apr-2023

Apply now to showcase your translational longevity research and win CHF 50,000

Ageing speeds up gene reading, reducing its accuracy

University of Cologne - 12-Apr-2023

Calorie restriction may extend lifespan by improving the quality of gene transcription

Gut Microbiome: The Secret to Longevity in Centenarians

Lifespan.io (LEAF) - 06-Apr-2023

A youthful gut microbiome may contribute to enhanced longevity and overall health in people living past 100

Meta-analysis studies relate autophagy mechanism with exercise in humans

Lifespan.io (LEAF) - 22-Mar-2023

The type of exercise can effect autophagy in humans, that in return can be an anti-aging strategy

Study shows it is critical for stem cells to prevent stress to preserve their health and longevity

News Medical - 21-Mar-2023

Therapeutics to boost regulation of protein homeostasis may be beneficial across multiple organs and pathologies

Cellular ageing signs emerge earlier in women than men

New Scientist - 19-Mar-2023

Machine learning analysis of millions of biopsy reports has potential implications for disease risk and treatment

Hypothalamic protein called menin found to regulate ageing and cognitive deficits

Interesting Engineering - 16-Mar-2023

Supplementing with the amino acid D-serine may reverse some anti-ageing effects

Lifespan.io interviews George Church about recent research and future anti-ageing treatments

Lifespan.io (LEAF) - 14-Mar-2023

Is involved in many longevity companies ranging from improving gene therapy delivery to supplements

Thymmune Therapeutics raised $7 million in seed financing

Biospace - 02-Mar-2023

Thymmune aims at developing therapies to treat several autoimmune diseases and organ transplant tolerance

Chroma secures new investment of 135M for Series B in genetic medicines

Biospace - 01-Mar-2023

Epigenetic medicine approach avoids the pitfalls of traditional CRISPR method of gene editing

Five Alarm Bio raises seed investment to discover small molecule anti-aging drugs

Cambridge Network - 27-Feb-2023

No drug candidates yet, but great to see investors willing to support a broad attack on ageing

Challenging Inflammaging in the Pursuit of Healthy Ageing

Live Forever Club - 24-Feb-2023

Chronic inflammation is lurking behind many age-related diseases, but also offers up many targets to reduce it

AgeCurve Ltd uses Cell tree rings and somatic mutation to calculate biological age

Longevity Technology - 13-Feb-2023

Those running geroprotective trials, academic researchers, clinical trial could use Cell tree rings

Analysis of gut microbiome relationship with longevity

Live Forever Club - 12-Feb-2023

A strong genetic correlation between healthy diverse gut microbiome and healthy ageing was found

Effects of intermittent fasting: An exploration

Live Forever Club - 31-Jan-2023

12 months of IF results in a range of biomarker improvements, but no significant reduction in inflammatory markers

Open genes-comprehensive database of genes associated with aging and longevity

Lifespan.io (LEAF) - 24-Jan-2023

Open gene database simplifies the search for potential aging therapy targets

Heart's biological age can be delayed by 10 years by an anti-aging mutant gene discovered

Medical Xpress - 23-Jan-2023

Healthy mutant gene can reverse the decline of heart performance in older people

Lifespan.io summarises the proceedings of the Buck Institute's Longevity Summit

Lifespan.io (LEAF) - 20-Jan-2023

Another reminder of the amount of research, with multiple approaches, about to go into clinical trials

Dissociation of longevity targeted cell reprogram and somatic identity loss: An exploration

Live Forever Club - 17-Jan-2023

Most genes regulating cellular rejuvenation were not related to the increased occurrence of cancer

Gut microbiota in mice influence brain's dopamine levels, influencing the motivation for exercise

Lifespan.io (LEAF) - 17-Jan-2023

The study highlights the diversity of microbiota and their importance for human health and fitness

Gut microbiome linked to brain damage and neurodegeneration in mice

EurekAlert! - 12-Jan-2023

Modifying gut microbiota with antibiotics reduced inflammation and tau-linked damage

Genome length and the relationship with ageing: An analysis

Live Forever Club - 06-Jan-2023

Identifies a new target for ageing therapeutics - maintaining the abundance of long RNA transcripts

Longevity Technology speaks to BioAge's CEO about clinical trial progress

Longevity Technology - 06-Jan-2023

Had success in reducing muscle atrophy and discovered novel class of molecules to target cognitive decline

Microbiome and metabolic biomarkers can predict who will lose the most weight

Stanford School of Medicine - 04-Jan-2023

Soon there will be a test to check what the best diet is for your individual microbiome

Nuclear homeostasis contributes to promote longevity and fertility, IMBB scientists

Institute of Molecular Biology and Biotechnology (IMBB-FORTH) - 27-Dec-2022

Cells fundamental quality control mechanism to safeguard the nucleus-promote longevity and fertility

SIRT6: Ageing, Metabolism, and Cardiovascular Diseases - A Review

Live Forever Club - 20-Dec-2022

SIRT6 has a vital role in cell metabolism which could lead to therapeutics for controlling senescence

Cellular Senescence Network (SenNet) to identify and characterize senescent cells

Nature Aging - 20-Dec-2022

Grand plan includes creation of imaging datasets, new tools, techniques, and biomarker panels

Exploring cellular enlargement as a new hallmark of aging

Live Forever Club - 12-Dec-2022

Size of various cells (including red blood, adipocytes, brain, heart) is seen to increase with age-related diseases

Turn Bio reverses multiple hallmarks of aging in human skin

CISION PR Newswire - 06-Dec-2022

Epigenetic reprogramming restores the production of collagen and elastin

Large scale study identifies new risk loci associated with CAD (coronary artery disease)

University of Oxford - 06-Dec-2022

The study outlines a list of genes and genetic variants for future study of common diseases

Microbes in your gut may affect your mental health

Oxford Population Health - 06-Dec-2022

Gut bacteria indirectly produce hormones that influence the brain and can cause depression

RxCelerate acquires Methuselah Health and launches proteomics platform ProQuant

Longevity Technology - 23-Nov-2022

Next-generation proteomics technology to accelerate drug discovery and development

Five Alarm Bio to develop drug treatment not to cure ageing but improve healthy lifespan

Cambridge Independent - 04-Nov-2022

The company aims at treatments for a range of diseases associated with ageing and disabilities

Lifespan.io interviews NaNotics' CEO Lou Hawthorne to find out more about Nanots

Lifespan.io (LEAF) - 04-Nov-2022

Many conditions could be improved by removing signalling that prevents cells operating at their best

Reprogramming by cellular rejuvenation in mice increases lifespan and health

Lifespan.io (LEAF) - 01-Nov-2022

Partial reprogramming extends healthspan and lifespan by single or lifelong treatment

Scientists unveil role of genomic 'dark matter' in cancer detection and treatment

BBC - 27-Oct-2022

Early but promising finding that epigenetic changes alter the growth of cancer cells

Universal epigenetic clocks predict true biological age in any mammalian species

Live Forever Club - 25-Oct-2022

Shared methylation patterns across mammals showed an association between ageing & development process in evolution

Reason reports back from October's Rejuvenation Startup Summit

Fight Aging! - 19-Oct-2022

Some really exciting developments with quite a few in clinical trials

Senolytics-a risky proposition in aging and repair mechanisms

Lifespan.io (LEAF) - 19-Oct-2022

The study is a caution for scientists engaging in self-experimentation with senolytics

Microbiome differences were associated with increased frailty, not chronological age

The Jackson Laboratory (JAX) - 19-Oct-2022

Skin microbiome emerged as the primary reservoir for infection risk associated with frailty

Calico-Terray Therapeutics collaborate to discover and advance therapeutics for diseases of aging

Calico - 12-Oct-2022

Terray’s novel microarray technology, combines wet lab and computer-driven drug development

Mitochondria boosting therapy rejuvenates immune system of mice

Longevity Technology - 11-Oct-2022

If successful in humans it would improve the outcome of many age-related diseases

Same chronological age women are biologically younger than the men

News Medical - 10-Oct-2022

Differences in biological aging between men and women - frequent smoking and larger body size of men

Researchers claim to have uncovered secret to immortality in jellyfish

Futurism - 01-Sep-2022

what this means to humans? - a possibility to treat overwhelming aging disorders

NICE - faecal transplants can be offered for hard-to-treat C. difficile

BBC - 31-Aug-2022

A solution to reduce both antibiotic usage and antimicrobial resistance

Ageing-related drug screening made easy and reproducible with automated tech

Longevity Technology - 18-Aug-2022

Camera on each petri dish captures healthspan of many worms simultaneously

72% of Induced pluripotent stem cell lines were reported to have major UV damage

University of Cambridge - 11-Aug-2022

Whole genome sequencing-necessary to validate Stem cell lines used for therapy

Mitophagy activators shown to increase lifespan and healthspan in C.elegans

Longevity Technology - 10-Aug-2022

Vitalunga to usher the novel drug for hepatocellular carcinoma clinical trials

Review identifies thousands of genes that drives skin ageing

Lifespan.io (LEAF) - 10-Aug-2022

Addresses challenges like phenotype list compilation and associated genes

Study shows the link between hibernation and longer lifespans in bats

College of Computer, Mathematical, and Natural Sciences (CMNS) - 09-Aug-2022

Overlap between the hibernation genes and the longevity genes links hibernation with longer life

Employing native bacteria as ideal chassis for therapeutic delivery and cure

UC San Diego School of Medicine - 04-Aug-2022

Re-engineered native bacteria serve as chassis to introduce therapeutics into the gut

SIRT6, the longevity sirtuin proven to enhance healthy longevity

Longevity Technology - 03-Aug-2022

SIRT6 Activator is a safe way to repair the genetic damages that may occur due to aging

Epigenetic age acceleration could be used as a biomarker for healthy longevity

University of California, San Diego (UCSD) - 27-Jul-2022

Accelerated biological aging associated with lower odds of living healthy and longer

Phase 2 clinical trial of lead drug candidate MYMD-1- a therapy for delaying aging

Business Wire - 26-Jul-2022

Sarcopenia drug trial shows no evidence of toxicity or safety issues

Age-related changes in retina linked to decline in 'youth' protein

National Eye Institute (NEI) - 18-Jul-2022

Aging associated retinal disorders linked to loss of protective protein

The genetics of successful ageing: unlocking longevity genes in humans

Live Forever Club - 11-Jul-2022

APOE and FOXO3A had significant impact on longevity, but environmental factors also determine the fate of health while ageing

Ageing versus longevity: epigenetic age correlated with only a few ageing hallmarks

Live Forever Club - 08-Jun-2022

Mitochondrial dysfunction & stem cell exhaustion accelerated the epigenetic clock, but senescent cells & telomere length did not

Hevolution Foundation to spend $1 billion annually on the biology of aging

MIT Technology Review - 07-Jun-2022

Considering funding a $100 million age reversal X Prize and the TAME(metformin) trial

Not just vision - diet and eye health is linked to aging in fruitflies

Buck Institute - 07-Jun-2022

Staring at gadget screens at night affects circadian clock and in turn lifespan

Lento bio to launch anti-glycation drugs targeting anti-aging and presbyopia

Ichor Therapeutics - 06-Jun-2022

Lento Bio research into molecular aging damage by accelerating clinical assets

Height may be an unrecognised non-modifiable risk factor for several health issues

The Guardian - 02-Jun-2022

Largest height study ever: being tall increases risk of peripheral neuropathy, lowers heart risk

Epigenome editing - technology safer and reversible than CRISPR

Science - 01-Jun-2022

Leaves DNA sequence unaltered while retaining the ability to specifically home

Longer lifespan lies in the mechanisms regulating gene expression

EurekAlert! - 31-May-2022

Pluripotency network can have negative and positive lifespan effects

The anti-malarial drug chloroquine increases lifespan in male mice

Lifespan.io (LEAF) - 30-May-2022

Chloroquine significantly interferes with the fundamental mechanisms behind autophagy

New algorithm recognises senescent cells using physical morphology

Lifespan.io (LEAF) - 26-May-2022

in vivo analysis in mice confirms the imaging results against p21 biomarker

Buck researchers discover mitochondrial protein that can increase lifespan

Buck Institute - 18-May-2022

In yeast, increasing Tom70 delays ageing related mitochondrial dysfunction

Lifespan.io interviews João Pedro de Magalhães about theories of, and curing, ageing

Lifespan.io (LEAF) - 13-May-2022

The one thing I hope he's wrong about is that it won't happen in his lifetime - we just need some exponential oomph!

Non-invasive technique for gut health monitoring

Swiss Federal Institute of Technology (ETH Zurich) - 12-May-2022

Gene modification in bacteria using CRISPR array provide direct information of active gut genes

Anti-ageing substance in sea squirts improved brain health in older mice

Neuroscience News - 11-May-2022

Plasmalogen supplement reversed ageing signs in mice; might as well keeps you young

The Observer interviews Morgan Levine about ageing and her move to Altos Labs

The Guardian - 07-May-2022

When it comes to lifespan, you cannot blame 100% on genetics, just 10-30%

Study in mice says faecal transplants could possibly reverse ageing

University of East Anglia (UEA) - 04-May-2022

Gut microbiome dictates and decides the health of your gut, eyes, and brain

First ever organ-on-a-chip functions like the human's body

Columbia Engineering - 27-Apr-2022

Opens way for personalized therapy, drug testing, and clinical extrapolation

Epigenetic age identifies risk of dementia later in life

Feinberg School of Medicine - 20-Apr-2022

Epigenitic and brain aging markers provide insights on accelerated cognitive decline

Mammals have similar number of DNA mutations whatever their lifespan

BBC - 14-Apr-2022

Shorter lived animals have higher rate of mutations - could explain lower rates of cancer in larger mammals

Turn Bio raised funds to usher epigenetic reprogramming from bench to bedside

Biospace - 11-Apr-2022

mRNA technology-reset aging to extend health span and improve quality of life

SENISCA to reverse senescence by targeting RNA splicing patterns

Longevity Technology - 08-Apr-2022

Lorna Harries details significant breakthroughs at fourth annual Longevity Leaders World Congress

Brain charts: showing the incredible growing and shrinking brain ability

University of Cambridge - 06-Apr-2022

Mapping the brain and creating charts could be used as a helpful clinical tool for other clinicians, psychiatrists and researchers

Genflow's sirtuin gene therapy can make old liver young again

Longevity Technology - 29-Mar-2022

Currently exploring the SIRT6 potential with University of Rochester’s Aging Research Center

Senior UCLA scientists public states aim to fight aging to impact numerous diseases

University of California, Los Angeles (UCLA) - 24-Mar-2022

Great to see the concept of reversing aging becoming a mainstream ambition - it hasn't always been that way!

Yellow-bellied squirrels stop ageing process while hibernating every year

Technology Networks - 08-Mar-2022

Organ preservation and life extension is possible when humans could also hibernate

University of Washington launches Rapamycin Study

Live Forever Club - 05-Mar-2022

Have you been taking rapamycin supplements recently? Please consider contributing to this study.

Maximon announces 50,000 CHF (approx. £40K) Longevity Prize for Translational Research

Maximon - 01-Mar-2022

And by longevity it means "substantially increase health span or life span" - apply now!

Longevity.Technology looks at 12 key companies running age-related disease clinical trials in 2021

Longevity Technology - 25-Feb-2022

Approaches include senotherapeutics, stem cells and mitochondria. Eye disease is a common first target.

Limiting calories rewires immuno-metabolic function for longer healthspan in humans

GEN News - 14-Feb-2022

Protein produced by macrophages was identified as a key player of calorie restriction

João Pedro de Magalhães provides cautious optimism in this Longevity Technology interview

Longevity Technology - 04-Feb-2022

Maybe a longevity drug within 5 years, but still lots more research needed into process of ageing

Google's parent company launched Isomorphic Labs to discover new drugs using AI

TechCrunch - 04-Feb-2022

Building from Deepmind's AI research, Isomorphic promises medical breakthroughs

ChromaDex releases results of clinical trial demonstrating anti-inflammatory effects of NR

Longevity Technology - 28-Jan-2022

Gold-standard trial included 35 participants taking 1000mg of NR (or placebo) for a week

Daily supplementation with urolithin A helps treat muscle fatigue

Medical News Today - 25-Jan-2022

Boosts mitrochondrial health & muscle activity in aged people and those who don't exercise enough

Biological age of single cells measured with high precision

Medical Xpress - 10-Jan-2022

Epigenetic age of individual cells helps tracking ageing process in various tissue types

Reason reviews progress in longevity research and treatments from 2021

Fight Aging! - 31-Dec-2021

There is a phenomenal amount of work going on across the spectrum of ageing - something is going to work eventually!

MyMD Pharmaceuticals begins phase 2 trial of TNF-inhibitor in January 2022

Longevity Technology - 14-Dec-2021

Potential oral treatment to prevent sarcopenia and frailty, and extend healthy lifespan

Interactive and comparative study of diet and drugs on the hepatic proteome

The University of Sydney - 15-Nov-2021

Dietary composition has a powerful impact on mitochondrial function

Rockfish that lives more than 200 years unveiled genes for longevity

Scientific American - 11-Nov-2021

Insights on longer-living species could offer the targets for extending lifespan in humans

A new model enter into telomere-mediated senescence to reduce genome damage

Genetic Engineering & Biotechnology News (GEN) - 10-Nov-2021

Telomeres repair can prevent senescence and genome instability

Gene-editing technology, CRISPR, selectively kills drug-resistant superbugs

Deutsche Welle (DW) - 10-Nov-2021

A single dose of CRISPR Cas system cleared 99.9% of harmful bacterial in mice

SENISCA targets sensescence using a new ageing hallmark - dysregulated mRNA processing

Lifespan.io (LEAF) - 03-Nov-2021

Lorna Harries believes dysregulated splicing as a breakthrough senotherapeutic target

New study leading towards permanent youthful immune function

Lifespan.io (LEAF) - 18-Oct-2021

Significant alteration in lineage potential by NR treatment in mice

Revel pharmaceuticals restores tissue function using AGE-cleaving enzymes

Longevity Technology - 12-Oct-2021

A unique treatment approach for ageing; will soon begin trials in animals and human cadaver tissue

Mammalian brain cells mapped for better understanding of the neuronal disorders

EurekAlert! - 06-Oct-2021

The atlas of the brain cells developed will help pave the way for future research in brain disorders

Longevity Science Foundation to fund $1 billion for a 120-year human lifespan

Longevity Technology - 30-Sep-2021

The foundation's mission is to make longevity medicine accessible to everyone - fantastic news!

The Rejuvenome project plans to combine multiple anti-ageing interventions in mice

Fight Aging! - 27-Sep-2021

One drug doesn't fit all; combination therapies to address multiple ageing processes at once

Smart toilets could provide effortless monitoring of a range of biomarkers, not just gut health

Guardian - 23-Sep-2021

Coprata and Toi Labs among companies looking to bring products to market in the next couple of years

Fewer mistakes in protein synthesis extends lifespan in simple microbes

Phys.org - 14-Sep-2021

Interestingly, rapamycin (and other drugs) also improves accuracy of protein production

Polygenic risk of age related diseases effect on human lifespan

GenomeWeb - 14-Sep-2021

Rare variants in non-coding RNAs are connected to various neurological disorders

Role of mature dendritic cells in thymic involution

Lifespan.io (LEAF) - 13-Sep-2021

Reversal of thymic aging possible through signaling based interventions

Complicated connection between protein shape and mitochondrial health, causing aging

Buck Institute - 07-Sep-2021

The “bad” process of pore opening and the “good” process of UPRmt - connection revealed

New CRISPR based stem cell implant releases drug as required in arthritis

GEN News - 02-Sep-2021

Reduced inflammation & bone damage in mice; relieves patients from their regular use of injections

Longest-lived bats unveiled secrets to longer and healthier lives

Medical Xpress - 26-Aug-2021

Novel genes increase DNA repair and limit damage to slow down ageing process

Summary of Eric Verdin presentation at End Age-Related Diseases 2021

Live Forever Club - 21-Aug-2021

Discusses causes and prevention of NAD depletion with a focus on CD38 consumption

Ubiquitination of cell proteins determines ageing and longevity in C. elegans

SciTechDaily - 21-Aug-2021

Levels of ubiquitin-tagged proteins affect lifespan - insights may find answers to longevity

Summary of Irina Conboy presentation at End Age-Related Diseases 2021

Live Forever Club - 20-Aug-2021

Very much looking forward to seeing published results on initial human pilot

SIRT6 variant plays a major role in preventing the aging process

Longevity Technology - 17-Aug-2021

Novel gene therapies to prevent the accelerated aging process

Scientists uncover patterns of metabolism in humans across the life course

BBC - 13-Aug-2021

Metabolism remained same throughout the mid-life and starts to decline only at 60 years

Hyperactivation of senescent cells can trigger cytokine storm

Lifespan.io (LEAF) - 13-Aug-2021

Stimulated senescent human umbilical vein cells showed high susceptibility to inflammatory diseases

Skeletal stem cells delay bone healing and foster inflammageing in older people

Medical Xpress - 12-Aug-2021

Treating with BMP2 and Csf1 antagonist in mice restored youthfulness to the aged skeletal system

New study links height loss and age-related cardiac deaths

Guardian - 09-Aug-2021

Get the measuring tape out, here's another biomarker to track!

Gut microbes show potential to reverse aging-related deterioration in brain

University College Cork - 09-Aug-2021

Microbiome in the gut could potentially slow down brain aging and improve cognitive functions

Role of muscle strengthening protein in reducing life span

Johns Hopkins School of Medicine - 04-Aug-2021

Activation of CaMKII improved muscle fitness but increased the risk of ageing

Scientists uncover mechanism that promotes ageing in mammalian stem cells

Medical Xpress - 02-Aug-2021

Evidence of cryptic transcription in older cells offers new strategies for longevity

Unique gut bacteria linked to healthy ageing in centenarians

Live Science - 30-Jul-2021

Fuels bile acids to prevent infections, but more research is needed to confirm its impact on longevity

Scientists find dormant regenerative abilities of the inner ear in mice

SciTechDaily - 30-Jul-2021

Advanced gene therapies can reactivate hair cells, which are vital for hearing

Levels of fatty acids in blood predict death in older people

Lifespan.io (LEAF) - 26-Jul-2021

Myristic acid, benehic acid, and omega 3 increase lifespan; palmitoleic acid lowers lifespan

Being wealthy at midlife may give you a longer and healthier life

Northwestern University - 23-Jul-2021

Lifespan differences exist even between rich and poor siblings/twins

Activation of telomerase gene prevents aging in certain types of cells

EurekAlert! - 23-Jul-2021

DNA region: VNTR2-1 plays a role in human aging and tumorigenesis

Scientists invent AI that predicts potential lifespan-extending compounds

Phys.org - 22-Jul-2021

Anti-ageing probability validated from a worm with human-like metabolism

Latest AI tool predicts proteins structures in just 10 minutes

SciTechDaily - 17-Jul-2021

Freely accessible software from GitHub to help scientists speedup their research process

Dr. Matt Kaeberlein argues for more funding for geroscience

The Hill - 16-Jul-2021

Chair of American Aging Association disappointed ARPA-H may only receive half the requested funding

Treatments that delay ageing could be worth trillions of dollars to the US alone

World Economic Forum - 15-Jul-2021

As more people live longer (lifespan) it is essential that their health keeps up too (healthspan)

Castration leads to longer life in male sheep, mediated by low androgens

EurekAlert! - 06-Jul-2021

There may be less men queuing up for this first generation longevity treatment!

Unique adaptations contribute to the longevity of American lobster

Medium - 04-Jul-2021

Insights on longevity, neural, and immune adaptations are revealed by a lobster

Long-term caloric restriction prevents age-related adiposity in aged mice

Lifespan.io (LEAF) - 02-Jul-2021

Targeting SA-T cells: A promising intervention to control age-related chronic diseases

DNAm GrimAge is a strong predictor of mortality independent of genetic influences

Fight Aging! - 30-Jun-2021

Twin study allowed impact of lifestyle factors on epigenetic aging to be determined

Zoledronate - accidental discovery of drug use for life extension

Lifespan.io (LEAF) - 30-Jun-2021

Too early to tell whether off-patent drug's effects in fruit flies will be seen in humans

Lifespan.io interviews Dr. Nir Barzilai about metformin, longevity genes and more

Lifespan.io (LEAF) - 29-Jun-2021

Optimistic on ageing research and a breakthrough human trial to extend healthspan

Eating less than 800 calories a day favoured weight loss via hungry pathogens

ScienceAlert - 27-Jun-2021

Long-term safety of the diet is questionable as it alters the healthy gut microbiome

Embryos reset biological age back to zero in early stage of development

Science News - 25-Jun-2021

Rejuvenation process in germline cells may help find new therapies for age-related disorders

Antibiotics extended the lives of the flies and changed their gene activity

Phys.org - 24-Jun-2021

In future, we can locate the genes which are linked to the aging process

Tryptophan-deficient diet alters gut microbiome, causing unhealthy ageing

Augusta University - 24-Jun-2021

Reduced beneficial gut bacteria and increased systemic inflammation in aged mice

Youthful stem cells delayed ageing through their secretions in mice

Lifespan.io (LEAF) - 23-Jun-2021

Potential stem cell treatment for age-related diseases, if succeded in human trials

Senescent immune system is a therapeutic target to extend healthy ageing

WVU Today - 21-Jun-2021

Degraded DNA repair in immune cells can cause premature ageing in the whole body

Stem cell therapy: A potential avenue for reversing pituitary gland ageing

Medical Xpress - 15-Jun-2021

Slowing down natural ageing process of pituitary glands with stem cells

Catalysis of TET1 - necessary for myelin repair in young adults

Genetic Engineering & Biotechnology News (GEN) - 08-Jun-2021

Regulation of adult remyelination in mice by TET1-mediated DNA hydroxymethylation

DNA-damage or telomere shortening may not cause normal ageing

EurekAlert! - 08-Jun-2021

Rapamycin fails to extend lifespan in telomerase-deficient mice, while improving lifespan by 39% in normal mice

Geography affects gut microbiome in healthspan and longevity

Fight Aging! - 07-Jun-2021

One treatment does not fit all - diversified gut microbiota needs customizable medicine

SIRT6 restores energy in older mice, increasing lifespan by 30%

ISRAEL21c - 01-Jun-2021

Overexpression of this protein delays frailty and overcomes age-related diseases

Excessive alcohol consumption makes women age faster

Lifespan.io (LEAF) - 31-May-2021

GrimAge clock presented accurate results on biological age than other epigenetic clocks

mTOR inhibitors reversed immune ageing to treat viral infections in older adults

Lifespan.io (LEAF) - 21-May-2021

Much needed approach to improve immune function during the COVID pandemic

SIRT6 overexpression delays ageing of heart cells in mice

Lifespan.io (LEAF) - 17-May-2021

Anti-ageing therapies targeting sirtuins may slow down multiple effects of human ageing

A snailfish modified its DNA for survival in the deep ocean

New Scientist - 13-May-2021

Yap hadal snailfish made extra genes to repair DNA & stay alive in high-pressure deep-sea waters

New immunotherapy clears out senescent cells to combat aging

Medical Xpress - 10-May-2021

Activated immune cells can treat age-related chronic diseases - a potential alternative to senolytics

Youthful gut microbiome rejuvenates ageing immune system

Fight Aging! - 05-May-2021

Restoring gut microbial health can reverse declining age-related immune fitness

Food odour nullifies lifespan benefits of dietary restriction in nematodes

Lifespan.io (LEAF) - 29-Apr-2021

You may have to avoid smelling, not just eating, food for CR to be effective

Intermittent fasting improves gut health to lower high blood pressure

Baylor College of Medicine - 29-Apr-2021

Correcting gut dysbiosis alters bile acid levels & may help manage hypertension in rats

Klotho protein reversed muscle ageing in old, but not older mice

eLife Sciences - 20-Apr-2021

Potential future treatment strategy to prevent sarcopenia when supplemented at a young age

Genes correlated for diseases with similar age at onset

Medical Xpress - 19-Apr-2021

UK Biobank study reveals genetic links & potential treatment strategies for age-related diseases

Diet and lifestyle changes reversed epigenetic ageing in males

Lifespan.io (LEAF) - 19-Apr-2021

Dietary, exercise, sleep, supplements, and breathing regimen for 8 weeks reduced epigenetic age by 2 years.

Dog Aging Project invites participants to study canine health and longevity

University of Washington - 13-Apr-2021

Understanding the impact of genes, lifestyle, and environment on ageing

Latest CRISPR editing method can turn on/off gene expression

Phys.org - 09-Apr-2021

Allows to silence bad genes without modifying the DNA sequence and it is fully reversible

SenNet: a new NIH initiative to fight ageing

Lifespan.io (LEAF) - 06-Apr-2021

Establishing a massive database on cellular senescence to improve human health

'Rogue' protein assists cancer progression in humans

The Scientist - 01-Apr-2021

Inactivating Siglec-XII could lower the risk of cancer, but more research is still needed

2021 NIA's lifespan extension study results on mice out now

Longevity Technology - 01-Apr-2021

Longer lifespan in old male mice treated with 17‐α‐estradiol, but four other compounds had no effect

Wild Biotech's unique database maps new targets for human diseases

Longevity Technology - 29-Mar-2021

Huge database of wildlife gut microbiota could screen potential therapies within days

CAR Macrophages for cancer immunotherapy enters phase 1 trial

The Scientist - 26-Mar-2021

Gene modified macrophages may surpass CAR T cells in treating solid tumors

A low-calorie diet maintains youthful gut state & improves lifespan

Fight Aging! - 24-Mar-2021

Calorie restriction prevents age-related changes to the gut microbiome in mice

Gene modified immune cells prevent cancer metastasis in mice

Medical Xpress - 24-Mar-2021

Signaling distant sites to alert & activate cancer killing immune cells in advance

João Pedro de Magalhães discusses longevity pharmacology and importance of human trials

Longevity Technology - 23-Mar-2021

Advances in longevity pharmacology to revolutionize healthcare with personalized therapies

BioAge's anti-ageing drug to treat Covid-19 enters phase 2 trial

Longevity Technology - 22-Mar-2021

Reverses immune ageing and can prevent death from coronavirus infection in the elderly

Canada's largest study of ageing raises $9.6 M infrastructure fund

Simon Fraser University (SFU) - 12-Mar-2021

Federal funding for CLSA advances ageing research, promoting health and well-being of older adults

Flagellin vaccine can help reduce harmful gut bacteria

Fight Aging! - 03-Mar-2021

Favorable results in single person experiment calls for a larger and formal research

Longevity pharmacology promises to revolutionize healthcare industry

Lifespan.io (LEAF) - 24-Feb-2021

Despite challenges, many companies and clinical trials in longevity field are constantly evolving

Goya et al review progress in cell reprogramming

Live Forever Club - 24-Feb-2021

Considers whether, and impact if, epigenetic clock is one component of a modular ageing mechanism

Gut microbiome impacts healthy ageing and survival in humans

Medical Xpress - 18-Feb-2021

Microbiome becomes unique starting in the mid-life, correlates with blood metabolites

Immune system links personality traits to lifespan

Irish Times - 17-Feb-2021

Insights on this missing link may offer new interventions for health and longevity in the future

Super summary of 3rd Annual Longevity Therapeutics Summit

Lifespan.io (LEAF) - 16-Feb-2021

More and more companies making greater and greater progress - 2021 could be an exciting year

Can short-term immune memory impact longevity?

Medical Xpress - 11-Feb-2021

Less inflammation due to shorter immune memory prolonged life of blind mole rats

Stool transplants help skin cancer patients respond to immunotherapy

Guardian - 04-Feb-2021

Poop to pill: fecal transplants restore healthy gut microbes boosting immunity to fight cancer

Proteins from parasitic worms could be the next anti-ageing therapy

Science Daily - 02-Feb-2021

Helminth parasites may provide protection against inflammation disorders

Lab-grown human muscle showed benefits of exercise

INVERSE - 29-Jan-2021

Tissue engineered muscle under simulated exercise prevented chronic inflammation

Automating healthy lifespan studies using nematodes

Kumamoto University - 28-Jan-2021

New automated system with AI searches genes, drugs to extend human healthy lifespan

Gerostate Alpha looks at ageing in an unbiased way

Longevity Technology - 20-Jan-2021

Instead of targeting specific hallmarks/pillars - they want to target ageing as a whole

New evidence on reversing cognitive ageing in aged mice

The Scientist - 20-Jan-2021

EP2 receptor which causes inflammation & ageing was knocked down in a disease model

Deactivating ageing gene KAT7 to slow down ageing

Reuters - 20-Jan-2021

A potential therapeutic target for ageing, but still a long way to human trials

Genes may partly influence your eating habits, study finds

Science Daily - 19-Jan-2021

Dietary indices found heritable food and nutrient patterns among female twins

SRF's End Of Year Campaign receives $1M from Antonov Foundation

SENS Research Foundation - 16-Jan-2021

Raises a total of $2M dollars this year amidst the pandemic

Interview with National Institute on Aging Scientific Director

Nature Aging - 14-Jan-2021

Most hallmarks of aging only described in mice, so far, but Luigi Ferrucci is still optimistic

A force of tissue stiffness could bring new changes to immune drugs

Buck Institute - 12-Jan-2021

Tissue stiffness alter immune system response to chronic diseases and ageing

Turn Bio licenses mRNA technology to undo ageing effects

Longevity Technology - 12-Jan-2021

A revolutionary technology research to provide the cure for age-related diseases

Scientists find the reason for impaired DNA repair in aged cells

Lifespan.io (LEAF) - 06-Jan-2021

Unveiled the mechanisms for DNA impairment; laid foundation for future research

Progress on human ageing studies with Dunkin Hartley guinea pig

Colorado State University - 06-Jan-2021

Animal model studies that help in better understanding musculoskeletal ageing

Andrew Steele shares his thoughts on ageing

Guardian - 03-Jan-2021

Echoes some thoughts from his book "Ageless: The New Science of Getting Older Without Getting Old"

Engineered genes in gut bacteria might help you live longer

Forbes - 23-Dec-2020

Green light activated E.coli genes, extending life in Caenorhabditis elegans

Points to consider in a biological clock

Aging Matters - 21-Dec-2020

Biological clocks should make sure they're using 'causes' and not 'effects' of ageing

A gene mutation that protects and improves brain function

Medical Xpress - 21-Dec-2020

Super agers with a rare gene mutation counteracts accumulation of aging proteins

Data from individual cells holds the key to a longer & healthier life

Science Business - 17-Dec-2020

Aim to intervene in ageing-related diseases before they cause harm. Sounds like curing ageing!

Highlights from eLife's Aging, Geroscience and Longevity Symposium

eLife Sciences - 17-Dec-2020

Authors covered biological age clocks, senescent cells, longevity genes, and more

Thymus regenerated from human cells in mice

Medical Xpress - 11-Dec-2020

Will help treat diseases due to immunodeficiency or autoimmunity

A new ageing clock that reveals your biological age

Longevity Technology - 09-Dec-2020

DeepMAge is an accurate ageing clock so far and could be a key in medicine

Early intervention before disease progression using glyhealth

Longevity Technology - 08-Dec-2020

Avenna's glyhealth alerts practitioners about subclinical chronic inflammation

Bioage's lead therapies moved closer to the clinic

Longevity Technology - 03-Dec-2020

Lead therapies of BioAge to treat age related diseases enter phase 2 trials

Genetically engineered T cells destroy pathogenic T cells in mice

Medical Xpress - 03-Dec-2020

Directing T cells to attack other T cells - a new treatment for autoimmune diseases?

Technology Networks interviews Prof Overall about the Human Proteome Project

Technology Networks - 01-Dec-2020

Proteomics is integral to accurate diagnosis and treatment for personalised medicine

MIT professor Richard Young explains how Omega regulates gene expression

Cell and gene - 01-Dec-2020

Using Epigenomic Controllers to alter DNA transcription rather than the genes themselves

Donations being triple matched for SENS end-of-year fundraiser

SENS Research Foundation - 01-Dec-2020

I've just donated to help #UnlockLongevity - these are the experts and they need funding!

Deepmind's AI program has decoded a protein mystery

Guardian - 30-Nov-2020

Will help in developing designer meds, better crops & 'green enzymes' to counter pollution

Number of births may decide how fast you age

Science Daily - 30-Nov-2020

Less than 3, or more than 4, results in accelerated ageing after menopause

Hidden inflammapath in your mouth invites deadly diseases

Longevity Technology - 25-Nov-2020

Keystone Bio's first ever biologic on the planet to eliminate oral pathogen

Eye-opening facts about human skin ageing

Chinese Academy of Sciences (CAS) - 25-Nov-2020

Therapeutic strategies to combat human skin diseases at single-cell level

A new FDA approved drug offers hope to children with progeria

Science News - 25-Nov-2020

Zokinvy blocks production of a defective protein to lengthen the shortened life span

Transgenic obese mice that do not suffer from being fat

Lifespan.io (LEAF) - 24-Nov-2020

Scientists discover a pathway to attenuate the deleterious effects of obesity

A rare gene mutant variant found to protect liver by chance

EurekAlert! - 19-Nov-2020

Scientists found exciting benefits by inducing a gene mutation in mice

A drug that reverses ageing to help fight COVID

Connecticut Post - 17-Nov-2020

Elderly have a higher mortality risk with COVID - reversing ageing could reduce it

Chronic inflammation promotes NAD+ decline during aging

Buck Institute - 16-Nov-2020

Senescent cells induce NAD+ decline via activation of CD8 macrophages

A new study links Alzheimer's to gut flora

New Atlas - 15-Nov-2020

Altering gut microbiome might be helpful in preventing or delaying Alzheimer's

Walnut - a super nut for a healthy heart

Genetic Engineering & Biotechnology News (GEN) - 10-Nov-2020

Decreases chronic inflammation and the risk of cardiovascular disease

Study links gut flora with Parkinson's and Alzheimer's

The Conversation (UK) - 10-Nov-2020

Microbiome altering might help in preventing or delaying Parkinson's and Alzheimer's

A novel approach unlocked a gene's purpose on immune system

Medical Xpress - 09-Nov-2020

Study in mice and humans found CRELD1 gene's role in immune cell aging

OTC drug Ibuprofen could reverse age associated inflammation

Longevity Technology - 06-Nov-2020

A study on mice supported ibuprofen for use in neurodegenerative diseases

Lack of gene coordination during aging calls for newer treatments

Bar Ilan University - 03-Nov-2020

Researchers found a new link in aging from a 15yr old approach

Scientists discover a life threatening inflammatory disease

WorldHealth.Net - 27-Oct-2020

Called VEXAS- discovered using a novel genome first strategy

A step towards understanding the molecular mechanism of ageing

Lifespan.io (LEAF) - 22-Oct-2020

A core set of genetic regulators involved in ageing have been found

Mechanism underlying telomere restoration in T cells discovered

Lifespan.io (LEAF) - 20-Oct-2020

Telomere transfer from APCs boosts T cells lifespan-helpful in immunosenescence

Genes of some species might hold the key to human longevity

The National Academies of Sciences, Engineering, and Medicine (NASEM) - 19-Oct-2020

Studying organisms that live long will help identify crucial genes associated with ageing

Improving immune system in the elderly with the existing medicines

The Conversation (UK) - 13-Oct-2020

Repurposing the potential existing drugs might eliminate the risk of developing infections

Tumor regression achieved with single 3-pronged immunotherapy injection

Lifespan.io (LEAF) - 29-Sep-2020

IL-12 self-replicating RNA delivered in lipid nanoparticles (LNPs) shows good results in mice

Everything you ever wanted to know about AKG (but were afraid to ask)

Lifespan.io (LEAF) - 07-Sep-2020

A great summary of the history,biochemistry and life-extending potential of alpha-ketoglutarate

Anti inflammatory peptides discovered in rice using Nuritas' AI program

Longevity Technology - 03-Sep-2020

Peptides reduce inflammaging and improve standardised physical tests

Longevity.Technology interviews Adam Freund - Calico’s Principal Investigator

Longevity Technology - 02-Sep-2020

Will be presenting a viable therapeutic strategy using IGF signaling at ARDD 2020

Body builder supplement AKG extends lifespan and healthspan of mice

Buck Institute - 01-Sep-2020

Blood levels fall with age. NUS planning a clinical trial with middle-aged humans.

IBM develops an online chemistry lab 'RoboRXN'

MIT Technology Review - 28-Aug-2020

Will lower the cost & speed up the process of developing drugs

90 % of herpes simplex virus 1 eliminated in infected cells

Lifespan.io (LEAF) - 19-Aug-2020

Successful in mice, new approach may ease immune burden of herpes in humans in the future

Middle-aged mice live 10% longer with 4 days of CASIN injections

Lifespan.io (LEAF) - 14-Aug-2020

It would be interesting to see how long they lived with regular treatment through old-age

Gut microbiome of centenarians changes a few months before death

Fight Aging! - 11-Aug-2020

Causation vs correlation to be confirmed - but death affects ALL cells in the body, not just YOUR cells

A protein for regulating circadian cycle also fights cellular senescence

Lifespan.io (LEAF) - 11-Aug-2020

Its upregulation could be a new prospect for anti-ageing interventions

Low stress hormone levels promotes premature ageing

Longevity Technology - 11-Aug-2020

Balance is key to everything especially with human body

Genes of the oldest humans alive hold the key to human longevity

Singularity Hub - 10-Aug-2020

This time, focusing on the narrow population, the centenarians, would give us answers

Longitudinal DNA methylation is influenced by genetic, environmental factors

Longevity Technology - 03-Aug-2020

Decade-long studies of identical twins were able to reveal connections

VRK-1/AMPK cellular energy pathway linked to longer lifespan

New Atlas - 02-Aug-2020

Early days, but looking forward to seeing the results (in vivo) in mammals

Omega Therapeutics raises $85m for Epigenomic Controllers

Endpoints News - 29-Jul-2020

New gene expression therapy for various targets, with clinical trial planned for 2021

Cohort study: Glucosamine reduces mortality by 15%

Fight Aging! - 28-Jul-2020

Supplementation with this anti-inflammatory drug can give us more benefits than we know

Abortion drug mifepristone may help extend the lifespan

Longevity Technology - 24-Jul-2020

Gains in fruit flies and roundworms give insights to extend human health and lifespan

LEAF interviews Reason about his views on epigenetic clocks

Lifespan.io (LEAF) - 22-Jul-2020

It does seem way to early to be settling for any single type of clock for rejuvenation research

Novel ageing pathway slows ageing of yeast cells in silico

CNN - 21-Jul-2020

It's a long way to go to having an effect in humans in vivo, but an interesting approach

Biological age of heart tissue 10 years younger then white blood cells

Fight Aging! - 20-Jul-2020

We need a single biological age figure as mortality risk applies to the whole body

Survey reveals unsettled views of ageing amongst researchers

Mechanisms of Ageing and Development - 18-Jul-2020

Good news is that almost half the researchers believe age reversal is possible - unimaginable 5 years ago

LEAF interviews Stephanie Lederman, Executive Director of AFAR

Lifespan.io (LEAF) - 17-Jul-2020

"I would say that the science is now for this field" - I couldn't agree more

Lowering iron levels might hold the key to longevity

ScienceAlert - 17-Jul-2020

Study finds link between ageing and elevated blood iron levels

Continuous trickle of genomic instability can lead to multiple age-related diseases

Lifespan.io (LEAF) - 16-Jul-2020

Analysing mutations in individual cells will help determine its burden on ageing damage

Balancing blood iron levels is the key to living longer

Phys.org - 16-Jul-2020

Genes linked to iron metabolism were also responsible for age related diseases

LEAF interviews Alexander Fedintsev about weak v strong ECM hypothesis

Lifespan.io (LEAF) - 15-Jul-2020

It may be a new hallmark of ageing, but it's been one of SENS' 7 strategies since it started

The blood-brain barrier selectivity is impaired with age

Lifespan.io (LEAF) - 09-Jul-2020

Experiments in mice confirmed this, unraveling ageing mystery if it translates to humans

Transplanting youthful white blood cells reduces inflammation in mice

Lifespan.io (LEAF) - 08-Jul-2020

Targeting immunosenescence could provide benefits throughout the body

Ageing seems to increase the number of repetitive elements in our DNA

Lifespan.io (LEAF) - 07-Jul-2020

Even if it's an effect (not a cause) then REs could act as another biological clock

LEAF interviews Edwina Rogers, CEO of the Global Healthspan Policy Institute

Lifespan.io (LEAF) - 06-Jul-2020

It's a different set of skills required to convince government decision makers to change policies

A novel cell therapy to reverse age related impairments

Science Daily - 06-Jul-2020

Physical fitness and immune health restored in aged mice models

Role of immune cells in reversal of aging process- A study in mice models

University of Bern - 06-Jul-2020

Manipulation of Eosinophils in belly fat to promote healthy aging

Hormone in bone restores memory and ability to exercise in old mice

Guardian - 04-Jul-2020

Exercising regularly increases this hormone and benefits muscle and brain

Low cortisol levels can trigger 'macrophaging'

Medical Xpress - 01-Jul-2020

Learning this age-induced disruption of macrophage functions powers pharmaceutical research

Trial of Rejuvant supplement claims 8 year age reversal

Lifespan.io (LEAF) - 30-Jun-2020

If randomised clinical trial replicates results then I might add it to my stack

Age-related diseases: Common genetic associations and therapeutic implications

Lifespan.io (LEAF) - 30-Jun-2020

With genomic database and statistical tools, more interventions can be discovered

Fewer genetic mutations gets few more years added to your lifespan

New Scientist - 24-Jun-2020

Will it be possible to remove such mutations from reproductive cells?

Scientists found a link to balance immunity and longevity

Max Planck Society - 24-Jun-2020

Gene changes in round worm lead an interesting evidence to longevity

Immunotherapy as new approach to battle senescent cells

Lifespan.io (LEAF) - 23-Jun-2020

Successful in mice, it may help treat many age-related disease in human

Forever Healthy Fellowship Program awarded to Dr. Tesfahun Admasu

Forever Healthy Foundation - 23-Jun-2020

His project researches on secondary senescent cells and SASP

Is it possible to predict biological age with gut microbiome?

Lifespan.io (LEAF) - 19-Jun-2020

Models and anti-ageing intervention design enables new ageing clock development

How lamins are linked to senescence and ageing

Lifespan.io (LEAF) - 19-Jun-2020

Connections have been elucidated but more research needed to confirm significant links

Gene mutations in DNA may impact lifespan and fertility

Newsweek - 19-Jun-2020

Study accelerated public awareness on genome sequencing & inspires new treatment approaches

Endless benefits of exercise also seen in gut microbiome

The Conversation - 16-Jun-2020

In both metabolic and physical levels, evidences gear towards positive effects

Peptides that shift gut bacteria can reduce heart attack risk in mice

Scripps Research Institute - 15-Jun-2020

Lowering the number of bad gut bacteria reduced artery plaques by 40% - wow!

SENS OncoSENS project suspended due to lack of funds and progress

Lifespan.io (LEAF) - 14-Jun-2020

It's important to keep funding basic research as no one knows where the answers will lie

Cellular pathway and mechanism leading to osteoporosis

Lifespan.io (LEAF) - 09-Jun-2020

Confirmed in murine and human cell study, findings can aid development of new treatments

Diluting blood rejuvenates old tissues in mice

Aging Matters - 08-Jun-2020

There are things in blood that drives our ageing

Eating less to live longer? Study in fruit fly finds no benefit

Science Daily - 04-Jun-2020

Life extending benefit of dietary restriction might depend upon genetic makeup

Experts devise newest epigenetic clock for anti-ageing drugs discovery

Lifespan.io (LEAF) - 03-Jun-2020

Showed impressive results based on experiments in vitro and in vivo, but more work to be done

Scientists develop a new epigenetic clock

Lifespan.io (LEAF) - 02-Jun-2020

The clock accurately predicts biological age & can help develop anti ageing drugs

BSRA sponsors funding to repair bone fractures in the aged

British Society for Research on Ageing (BSRA) - 01-Jun-2020

Chernajovsky Foundation with BSRA funds for PEPITEM molecule to treat fractures

ThirdLaw may have designed a way to break crosslinks to reverse tissue ageing

Longevity Technology - 29-May-2020

Whoever controls the shape of a molecule controls what it can do

Experts develop new novel detection method for mitophagy

Lifespan.io (LEAF) - 28-May-2020

A discovery proven to be of help in therapeutic studies of neurodegeneration

Mice blood proteome analysis reveals new therapeutic target for osteoporosis

Lifespan.io (LEAF) - 26-May-2020

A different perspective for preventing age-related bone loss that affects many

Epigenetic clock of asthma patients reveals valuable information

HCP Live - 22-May-2020

There are lot more to discover and learn about asthma

Age-related changes in gut microbiota cause cognitive decline in aged rats

Lifespan.io (LEAF) - 20-May-2020

Restoring microbiome could be one strategy to support healthy longevity

Human gut microbiome is altered by shifting to a ketogenic diet

EurekAlert! - 20-May-2020

Potential research area to find treatment options for autoimmune diseases of the gut

An anti ageing protein found in yeast cells

The Conversation (UK) - 20-May-2020

Works by inhibiting protein metabolism

Orion College ageing research receives 1 million UK pounds from Jim Mellon

Lifespan.io (LEAF) - 18-May-2020

He believes in the importance of boosting immunoresilience among elderly

This enzyme helps reverse age-related neurodegeneration in mice

EurekAlert! - 18-May-2020

Sheds light to potential treatments for age-related cognitive decline, Alzheimer's

Metformin alleviates inflammaging by promoting autophagy

Lifespan.io (LEAF) - 14-May-2020

With the positive results, drug holds great promise for promoting healthy ageing

The effect of gut microbiota on cognitive decline in aged rats

Fight Aging! - 14-May-2020

First study investigating its effects in the normal ageing process

Immunai, to map immune system for better diagnosis, disease treatment

Healthcare IT News - 14-May-2020

This application of machine learning will soon speed up drug development

Josh Mitteldorf stakes his reputation on major rejuvenation in a mammal

Aging Matters - 11-May-2020

Imagine halving your age with 4 simple injections - at the very least it will buy more time

Should WHO use a new framework for the diagnosis and treatment of age-related diseases?

Lifespan.io (LEAF) - 08-May-2020

LEAF summarises and exchange of thoughts between leading aging researchers

LEAF interviews Daria Khaltourina about WHO classification of ageing

Lifespan.io (LEAF) - 05-May-2020

Believes life extension treatments may already exist - but need more clinical trials

Pace of human biological ageing can now be measured via blood test

Columbia University Mailman School of Public Health - 05-May-2020

Can aid future trials of therapies aiming at preventing diseases and slowing ageing

Commercial glycan test kit can tell the biological age using a dry blood spot

Longevity Technology - 05-May-2020

Analysing IgG glycosylation: is it the most accurate measure of biological age?

DunedinPoAm: a speedometer that tracks the rate of ageing using methylation biomarkers

Science Daily - 05-May-2020

A simple blood test could reveal if you are ageing faster or slower than your peers

Altering macrophage epigenetics to prevent lumbar disc degeneration

Lifespan.io (LEAF) - 04-May-2020

Findings can lead future treatments for age-related conditions caused by inflammaging

Coffee clearly does something to our DNA

Food & Wine - 01-May-2020

Maybe it's good, maybe it's bad - still too early to say for sure

The integral role of gut microbiome in precision medicine

AACC (American Association for Clinical Chemistry) - 01-May-2020

Huge potential in a more personalized diagnostics and diet-based disease interventions

GlycanAge offers free biological age blood tests in the UK

CISION PR Newswire - 29-Apr-2020

1,000 free tests available in May - but be quick, my names already on the list!

From the organisers for RAADFest - a free webinar - Eyes on the Prize

Coalition for Radical Life Extension - 23-Apr-2020

Will be discussing important advances in age reversal - looks interesting (and did I say FREE?!)

DNA alterations in rod photoreceptors, linked to age-related eye diseases

Medical Xpress - 21-Apr-2020

First study to look at DNA methylation changes as mice age and how it affects visual function

Nature to launch new journal dedicated to the broad spectrum of aging research

Nature - 21-Apr-2020

Anti-aging research is becoming main stream, because NOBODY is researching how to speed it up!

How external factors could influence Alzheimer’s disease via the gut microbiome

Lifespan.io (LEAF) - 20-Apr-2020

Early study into complex neurochemical relationship between brain, gut and inflammaging

Inhibiting p38 MAPK rejuvenates resolution response in elderly

Lifespan.io (LEAF) - 15-Apr-2020

A new perspective on mitigating the effects of inflammaging, promoting health in older people

The importance of early life microbiome in gut protection

Lifespan.io (LEAF) - 10-Apr-2020

Demonstrated in neonatal mice microbiome mediating an immune response

Dawn til dusk fasting improves blood biomarkers

Lifespan.io (LEAF) - 08-Apr-2020

Small study (14 participants) with strict participation requirements, but interesting biomarker results

Resveratrol reduced DNA double-strand breaks in mice cells

Lifespan.io (LEAF) - 06-Apr-2020

Variety of polyphenols had positive impact on genomic stability

Gut enzyme prevents age-related loss of intestinal barrier integrity

Lifespan.io (LEAF) - 03-Apr-2020

In animal models, IAP is found to prevent frailty and extend lifespan

Proposed strategy to protect elderly from gerolavic infections like COVID-19

Forbes - 31-Mar-2020

To benefit long term global health and longevity, and enhance economic recovery

Gut microbiota highly influenced by ageing and dietary fat intake

Lifespan.io (LEAF) - 30-Mar-2020

Several short-term responses and alterations are evident in a mice study

Healthy old-people's poo improves gut microbiome of mice

Lifespan.io (LEAF) - 20-Mar-2020

Healthy gut means healthy body. Thought there are alternative ways of increasing probiotic bacteria!

Stability of splicing regulation, key to naked mole-rat longevity

Fight Aging! - 16-Mar-2020

Mechanism behind their exceptional lifespan and prolonged healthspan becoming clear

FDA issues safety alert for stool transplant after string of infections

Healio - 13-Mar-2020

Safety concerns alerted OpenBiome to recall unused materials and test donors in screening process

Why people should take up a career in the aging research industry

Lifespan.io (LEAF) - 26-Feb-2020

I think Victor is right, anti-aging is going to be the next big thing

The new quality control system that clears misfolded proteins outside cells

EurekAlert! - 18-Feb-2020

Opens new pathways for treatment of disorders such as Alzheimer's disease

Werner syndrome and normal aging epigenetic signatures differ

Fight Aging! - 17-Feb-2020

Werner syndrome, not merely accelerated normal aging as previously thought

Skin microbiome provides the best prediction of age

Lifespan.io (LEAF) - 14-Feb-2020

It will be more easy and convenient to take samples from skin and saliva, rather than fecal samples

Chronic inflammation leads to inflammaging

Medical Xpress - 29-Jan-2020

If we can slow down inflammaging we may be able to achieve longevity

David Sinclair Ask Me Anything - best bits

Lifespan.io (LEAF) - 22-Jan-2020

Always interesting to hear what Dr Sinclair has to say

Fight Aging! reports back from SENS Research Foundation Pitch Day

Fight Aging! - 20-Jan-2020

When some of these succeed in human trials even more money will pile in to fund further advances

An enzyme that prolongs lifespan in roundworms discovered

INVERSE - 07-Jan-2020

Results have been replicated in cultured human cells - a new hope for life extension?

Can we treat the ageing process or not? That's the question

UCSF - 02-Jan-2020

John Newman, UCSF asst prof & Buck Institute researcher, explains upcoming ageing interventions

Longevity Leaders' latest report on how longevity is disrupting the world

Longevity Leaders (LSX) - 01-Jan-2020

An interesting collection of interviews and white-papers with industry leaders

Josh Mitteldorf argues for the minority view on methylation changes

Josh Mitteldorf Blog - 23-Dec-2019

Are epigenetic changes the cause or a symptom of ageing?

Scientists discover a master regulator of cellular senescence

Medical News Today - 19-Dec-2019

Solving the mystery of ageing - still at the beginning

Rapamycin causes mTOR inhibition having an impact on mammalian aging- Brian Kennedy

Lifespan.io (LEAF) - 04-Dec-2019

mTOR pathway, part of the deregulated nutrient sensing hallmark of aging

Long live the dogs - an attempt to increase lifespan of man's best friend

CNN - 15-Nov-2019

Dog Aging Project plans to recruit dogs from all 50 states

Could immune cells be the secret to extreme longevity?

Live Science - 15-Nov-2019

Unusually high concentrations of T helper cells found in supercentenarians bloodstream

High levels of killer cells in the immune system of supercentenarians

Medical Xpress - 13-Nov-2019

Relatively immune to infections and cancers - also get to live more than 110 years

Mr Senescence explains how to speed up ageing research

Lifespan.io (LEAF) - 05-Nov-2019

Long validation times in ageing research – experimental time is a bottleneck

Could you live longer with minimal brain activity?

Big Think - 25-Oct-2019

Gene regulation calmed high neural activity and prolonged life in mice & roundworm

Huda Suliman explains the nuances of drug discovery in ageing research

Lifespan.io (LEAF) - 23-Oct-2019

Indications are less clear with anti-ageing compounds than with disease specific drugs

TAME Metformin Trial: An Editorial by Aubrey de Grey

Fight Aging! - 22-Oct-2019

Is it really the best use of $75M in the crusade against aging?

Protein misfolding ruins the young and beautiful cell

Phys.org - 17-Oct-2019

Presence of free radical damage significantly reduced the lifespan in worm model

LEAF Interviews the NIA's Deputy Director Dr. Ronald Kohanski

Lifespan.io (LEAF) - 16-Oct-2019

Systems biology discovers the networks that are essential for a living organism

Microbiome therapies can soon be personalized using a digestive tracker

NutraIngredients - 09-Oct-2019

Carbiotix and Food Marble partnered to correlate gut microbiome with digestive health data

Is senescent cell clearance a zero sum game?

SENS Research Foundation - 06-Oct-2019

Research suggests senolytic treatments will be beneficial for at least a few decades

Longevity.Technology interviews Buck Institute’s President and CEO Eric Verdin

Longevity Technology - 03-Oct-2019

Includes updates on NAPA Therapeutics and BHB Therapeutics

Skin cancer survival rate up jumps 10-fold in just 10 years

BBC - 28-Sep-2019

UK doctors announce that more than half of the patients can now survive advanced melanoma

Harvard associate professor looks at 5 common ageing myths

Washington Post - 20-Sep-2019

The science is changing all the time, we've still got a lot to learn

Interview with Aubrey de Grey - Longevity.Technology Exclusive

Longevity Technology - 12-Sep-2019

Great intro to life extension's leading advocate - Aubrey predicts radical change within 5 years

LEAF Interviews Dr. David Sinclair, Prof. of Genetics at Harvard Medical School

Lifespan.io (LEAF) - 10-Sep-2019

He started taking resveratrol in 2003, and now added NMN and some metformin

LEAF interviews David Sinclair about NMN trials and epigenetics

Lifespan.io (LEAF) - 10-Sep-2019

He's optimistic that human trials will convert the majority of people who are skeptical or unaware

Leukocyte telomere length found to be linked to DNA methylation (DNAm)

News Medical - 02-Sep-2019

Yet more evidence that hallmarks of ageing are inter-related, not standalone actions

Gut and oral human microbiome, mapped

Science Daily - 19-Aug-2019

Study reveals links between bacterial genes and disease risk, key to future protection

Electrical stimulation therapy to ears improved body, sleep and mood

BBC - 30-Jul-2019

Newly discovered benefit of transcutaneous electrical nerve stimulation

Time to focus in on health extension rather than life extension

The Atlantic - 21-Jun-2019

Longer healthspans will inevitably result in longer (and longer, and longer...) lifespans

Developmental stages of anti-ageing treatments

Next Big Future - 09-Jun-2019

Two anti-ageing treatments in phase 3 clinical trials and four in phase 2 clinical trials

Right time to adopt "anti-ageing" lifestyle

News Medical - 07-Jun-2019

Key molecular programs known to promote longevity do not last beyond midlife

Insilico and ARK enter a research collaboration on health-span and longevity

EurekAlert! - 22-May-2019

AI-based methods, to explore mechanisms of ageing and improving health-span

Mysterious epigenetic marks and their impact on our life

Mosaic - 21-May-2019

Yamanaka factors may be the solution for reversing age-related diseases

SIRT6 gene improves DNA repair and increases lifespans

University of Rochester - 19-Apr-2019

Could it be tweaked to be even more efficient?

New class of drug destroys, not just inhibits, proteins

Nature - 20-Mar-2019

Cancer targeted first, but could clear out age-related proteins in future

resTORbio Agrees Phase 3 Human Trials with FDA

Lifespan.io (LEAF) - 19-Mar-2019

If successful, drug could be available in next few years

Reducing Inflamm-Aging by topical skin application, beneficial in chronically aged

University of California, San Francisco (UCSF) - 13-Mar-2019

Rejuvenating the skin can reverse “inflamm-aging may have profound health effects

Academy for Health and Lifespan Research Q&A with Harvard's David Sinclair

Harvard Gazette - 08-Mar-2019

Rejuvenation human trials (cell reprogramming) possible in next 2 years

Aubrey de Grey shortens timeframe for human rejuvenation

Next Big Future - 28-Feb-2019

Once proven in mice, demand and funding will surge

New academy to lobby government to combat ageing

The Boston Globe - 12-Feb-2019

Will campaign to treat ageing as a disease

Unlocking the secrets of ageing hidden in blood cells

Medical Xpress - 07-Feb-2019

Blood cells have their own agenda for ageing and other cells don't have a say in it

Aubrey de Grey predicts age reversal trials in 5 years

Lifespan.io (LEAF) - 13-Dec-2018

Not yet predicting the end of aging, but first generation damage repair therapies.

BioViva developing an anti-aging vaccine

Precision Vaccinations - 12-Dec-2018

Developing a virus to express several anti-aging and regenerative factors

2019 SRF Summer Scholars Program - applications open now

SENS Research Foundation - 01-Dec-2018

Great opportunity to work with some of the best minds in aging research

New study finds your genes may not influence your lifespan

Science Daily - 06-Nov-2018

Family tree data suggests hereditary genes contributed to no more than 7% of a person's lifespan

Josh Mitteldorf thinks his and Aubrey de Grey's views are converging

Aging Matters - 08-Oct-2018

Even if signaling is fix, I suspect that there will be some damage already done that needs repairing

Stealthy Harvard startup wants to reverse aging

MIT Technology Review - 09-May-2018

Rejuvenate Bio is cofounded by George Church of Harvard Medical School.

Undoing Aging 2018: an initiative to remember

Long Long Life - 22-Mar-2018

45 speakers, scientists and entrepreneurs, presented their work.

Immunethep seeks funding to take its novel bacteria vaccine into clinical trials

Labiotech - 09-Mar-2018

Alexander Burik sensibly advises caution about any new type of treatment

Harvard’s David Sinclair Treats Aging as a Disease

W Xpress - 07-Mar-2018

WuXi interviews Harvard University’s David Sinclair

Carbiotix offers low-cost, personalized gut health testing service

NutraIngredients - 25-Jan-2018

New microbiome test kit provides customizable supplement dosing to fill the fibre gap

DanBrit acquires Enochian Biopharm to expand its immunotherapy pipeline

CISION PR Newswire - 23-Jan-2018

Will rebrand as Enochian and also move to Los Angeles

Molecule could revert cellular ageing

University of Lisbon - 08-Jan-2018

Non-coding RNA is never translated into protein.

Aging Research Half a Lifetime Ago: the Lost Decades of the 20th Century

Fight Aging! - 02-Jan-2018

Microbiome analysis: some gut bacteria reduces inflammation

Guardian - 09-Dec-2017

Village peasant microbiome has low risk for atherosclerosis, obesity, diabetes and colitis

SRF has made progress in the fight against ageing

Lifespan.io (LEAF) - 05-Dec-2017

R&D phase in SENS repair approach has shown promising results

SRF to develop glucosepane-cleaving antibodies with Spiegel Lab

Lifespan.io (LEAF) - 17-Sep-2017

Anti-glucosepane antibodies may offer new therapies for age-related diseases

RNA splicing could help us prevent aging

Futurism - 06-Dec-2016

Researchers wanted to find out the impact of RNA splicing on the ageing process

Young blood therapy - the real deal to longevity?

h+ Magazine - 02-Apr-2013

Transfusing youthful blood factors into an older patient could be a reality soon

Molecular clock reversed in mice using SIRT3 infusion

Fight Aging! - 31-Jan-2013

Could SIRT3 promotion in humans help with age-related oxidative stress?