Springy synthetic cells supercharge T-cell immune response
UCLA Samueli School Of Engineering - 25-Nov-2024UCLA unveils viscoelastic antigen mimics to boost immunity and fight cancer
Join the club for FREE to access the whole archive and other member benefits.
UCLA unveils viscoelastic antigen mimics to boost immunity and fight cancer
Therapies targeting senescence cells show promise for controlling cancer progression
Targeted drug delivery and immune boost for personalized cancer therapy
Experts believe expanding this initiative could help save more lives
In trials on mice, the drug reduced tumors, promising new cancer treatments
New tech at NHS trusts speeds up cancer detection in high-risk areas
Tailored drug dosing could reduce harmful reactions for cancer patients
Unravelling tumour dynamics to enhance cancer treatment
A new trial offers hope for glioblastoma patients as innovative treatment yields significant results
Study suggests a healthy diet may reduce the risk of cancer advancing during active surveillance
The technology extends survival for some patients by 3.3 months
New funding accelerates the development of a novel neutrophil-based solid tumour treatment
Innovative £120 test could identify 12 common cancers, revolutionizing patient care and saving lives
Clinical trial shows treatment extends survival for patients with advanced lung cancer by over 40%
Scientists aim to harness the immune system to fight cancer in its earliest stages
New research highlights the role of gum disease-related microbes in increasing cancer susceptibility
Findings cover brain and head cancers, hinting mobile phones might be safe
Aston university creates a non-invasive test that detects prostate cancer in minutes
New stem cell breakthrough offers personalized cancer treatment with less rejection risk
Newly discovered protein may lead to cancer vaccines and advanced DNA repair
New mRNA-based vaccine takes center stage in promising lung cancer care
This has led to better early cancer detection and improved patient care
Researchers developed a "CD3 Score" to measure immune cell levels in tumours
C the Signs spots hidden patterns in patient records, leading to faster and early cancer diagnoses
The system works by being activated in acidic tumour environments
This approach is a simpler alternative to existing cell therapies for cancer
The treatment was most effective when combined with a bone-strengthening drug
Nearly 90% of cases are preventable, linked to excessive UV radiation
Research holds the key for early detection and prevention of cancer
Greater convenience for patients and could potentially reduce NHS costs
Trial shows promising results for a potential cure, targeting individual cancer cells
Test offers minimal benefit but risks overtreating slow-growing cancers
In an NHS trial, the system successfully identified cancers missed by human doctors
It may improvepatient outcomes and advance personalised cancer treatment
Prostate, breast, liver, and kidney cancers are driving this increase
ASTR to revolutionize cancer treatment with unmatched precision & minimal tissue loss
The approach may lead to earlier disease detection & better treatments
Pi's accuracy might save healthcare costs and free up resources
This could lead to more personalised treatment plans and better outcomes
Research shows 57% reduction in lung cancer risk for those who quit before 50
Linked to unhealthy habits like smoking, drinking, and eating too much red meat
Patients will receive three doses of the vaccine before surgery
Technology offers a glimpse into the future of personalised cancer care
New, more efficient approach for personalized bladder cancer treatment
Provides oncologists with a precise tumor genetic map for selecting treatments
Test reported high sensitivity and specificity, better than other similar assays
CAR T cells are modified to produce interleukin-10, a molecule defeating various cancers
Carnosine, a molecule also produced by the body, has shown impressive abilities
Progress with early detection, but treatment delays and funding pressures demand urgent attention
A novel way to beat cancer in the lab showing promise in mice
Calls for stricter UK regulations arise, as other regions impose lower PFAS limits
Bold plan needed to fix NHS, boost research, and end preventable deaths
The acid eliminates tumours by activating immune cells to combat cancerous cells
Device uses non-invasive magnetic fields to increase ROS levels in cancer cells
Smoking tobacco alone results in a loss of at least 20.8 million years of life
KDM1A emerged as dual-action therapeutic target for both
Increased vaccination and improved screening are key to achieving the target
Restoring touch and confidence with a revolutionary medical breakthrough
Anastrozole could prevent risk of disease by 50% among eligible women in England
Scientists call for new interventions to promote effective sun protection
PM2.5 particles can penetrate deep into tissues and promote cancer growth
Dostarlimab with 100% success rate in early trials offers hope for bowel cancer patients
ABBV-CLS-484 enhances anti-tumor immunity and is currently in clinical trials
Device uses sensor technology to apply human-like forces with precision
Implant continuously monitors cancer and adjusts immunotherapy dose in real time
The trial could help to match right treatment to people with rare cancers
Study in mice finds that antioxidants stimulate the growth of cancer tumours
New treatment for a paediatric cancer (rhabdomyosarcoma) could save lives
Low vitamin D was mainly linked to high mortality risk from stomach, prostate, bowel, and lung cancers
Highly precise shape-sensing technology to help clinicians diagnose & treat lung cancer at early-stage
Gallium-based particles synthesized to heat with light and help immune system to kill cancer cells
Use of AI supported screening can help reduce workloads and patient wait times
Experimental drug enters phase 1 human trials - offers hope for personalized and targeted cancer therapy
Multipronged T-cells recognize multiple target proteins and attack cancer in many ways
Magnetically guided nanotubes effectively killed cancer cells in mice
NBTXR3 to enhance the effect of immunotherapies; plans for phase 3 trial in head and neck cancer
Overweight and obese is linked to developing 18 cancer types - early prevention is the key
Groundbreaking InnerEye AI, developed by Addenbrooke's Hospital and Microsoft, revolutionises radiotherapy planning
Offers promising results in the detection, and original site, of over 50 types of cancer in major NHS study
IMAN therapy targets tumours and activates the immune system against tough-to-treat cancers
Potential to fast-track patients to treatment and streamline CT scan analysis
Covid-19 pushed through a decade's research and testing into a year, results of which could have much wider impact
From diet to lifestyle, experts explore potential culprits behind this worrying trend
T cells are trained to recognize cancer antigens, which attack the cancer cells when reintroduced into the body
67% fewer men experienced risks of screening with advanced diagnostic techniques
Painless, quick, and non-invasive method to potentially transform breast cancer screening
Study identifies biological mechanisms including efficient DNA repair, no thymic involution and dampened inflammatory response
Advancements could enable early detection of various cancers via membrane proteins in urine
Studies also link UPFs with heart disease, obesity, type 2 diabetes besides cancer
Getting diagnosis within seconds could enable women confirmed to have cancer start treatment sooner
A 51-year-old patient in trial is now cancer-free with immunotherapy drug and chemotherapy
Phase IIb trial on skin cancer showed positive results, with 44% lower risk of death
Base editing can soon be a part in taking control of our genomes to fight genetic diseases
Capivasertib could become a game-changer for advanced breast cancer patients
NR fuels the energy levels of both cancer cells and cancer-fighting cells according to the study
Research reveals that nicotinamide riboside (NR) may fuel cancer spread
Personalized T-cell therapy for untreatable cancers - further studies needed to test the dose and effectiveness
This expansion follows earlier FDA approval in the U.S. With financing from JPMorgan
Mutations in a telomere binding protein provide a new approach to treat melanoma and other cancers
Early but promising finding that epigenetic changes alter the growth of cancer cells
Weakened form of herpes virus showed promising results for various advanced cancers
LIfT Biosciences' N-LIfT therapy targets and destroys tumours with a unique immune-based approach
Mutations alone are not always enough for tumour formation
NBTXR3 might give hope to patients who are ineligible for certain chemotheraphy
Clarity on cell particle interaction and particle uptake, for specific cancer types
Utilising new technologies and tests to detect and diagnose cancer at early stages
High death rates in men due to skin cancer point out the need of sun safety
Bacterial microrobots activate immune response and release drugs directly at desired tumor sites
Nitrites and nitrates as preservatives in cold cuts linked to colon cancer
The insects’ antennae are the most important for detecting cancer
Latch recognises low pH environment around cancer cells for penetration
Radiation-induced damage may lessen by removing senescent cells but senolytics may not reverse the damage
AI based-DERM could speed up diagnosis by replacing dermatology appointments
Chemotherapy treats patients but the lethal effect could be gotten down by preliminary testing
Instead of caterogising cancer based on the effected body part or type, whole-genome sequencing could be more practical
Genetic analysis could show how being obese could increase the risk of endometrial cancer
Experimental gene therapy shrunk tumor size by 50% within three months
Identifying faulty genes and matching cancer patients to potential experimential therapies
Game changer in cancer treatment by improving early access to drugs and thereby survival rates
Ultra-low toxicity NaNots could have a wide variety of applications
Electric current damages the cell membranes of the cancerous cells
Evaluates the safety and anti-tumor efficacy of oral cirtuvivint in cancer patients
Retrotransposons activate immune response against precancerous cells - may have implications in humans
Virtual cancer tumours can be grown and we can design personalised nanoparticles to treat them
AI-powered software can be an alternative for expensive and extensive lab work
Enhertu improved overall survival rate in breast cancer patients
People in Queensland can sign up to partake in the screening trial at Brisbane
mRNA cocktail treatment shows anti-tumor effect without toxic side effects in mice
Prior study approval and monitoring long-term outcomes are needed to ensure patient's safety
Overcomes a long trial and error process and accelerates personalized treatment
Deep learning could improve diagnosis of non-white skin lesions if trained correctly
Supports ageing research and advancing early-stage projects to phase 2 trials over the next decade
Large, long living animals offer insights on natural ways of cancer resistance
Screening cancers non-invasively; shows safety in phase 1 trials
Provides early diagnosis in younger women, eliminating pain and discomfort
Improved survival rates for lung and skin cancer, thanks to new FDA approved therapies
Latest AI platform developed to improve diagnostic accuracy of prostate cancer
Early stage detection of cancer has highest chance of cure
Killing the invisible cancer cells with unique gamma delta T lymphocytes
Technology suitable for meeting the lab requirements to deliver the service
People in Hampshire and Yorkshire will be invited for participation in the trial
Treating the incurable - robotic technology improved precision and accuracy of surgeons
Improvement in quality of life by 5 to 10 years in cancer patients
Precisely targeted therapy shrank tumours and extends life by 38% in men
SkinVision helps to detect skin cancer at an early stage when its most treatable.
Patient-specific cell therapies under clinical trials for treating lung cancer and melanoma
This could be a major breakthrough, but with a 100% accuracy claim it definitely needs reproducing
Breakthrough strategy involving fusion of drug carrier membrane with the cell
Nose reconstruction made less invasive with 3D bioprinting, plans for human trails in 2-3 years
Interesting drug delivery approach with rotaxanes to improve drug efficiency & reduce side effects
Cryoablation system using liquid nitrogen sets new standards for treating breast cancer
Inactivating Siglec-XII could lower the risk of cancer, but more research is still needed
New therapeutic alternative to prevent cancer progression by suppressing the causative agent SETDB1
Gene modified macrophages may surpass CAR T cells in treating solid tumors
Signaling distant sites to alert & activate cancer killing immune cells in advance
Science behind developing Covid-19 vaccines could bring us cancer shots too
Positive evolution, gene duplications are linked to longevity and anti-cancer traits of cetaceans
Real injectable robots delivering drugs exactly where they're needed - the future is here!
Eos Advisory and Kineticos collab will help find treatment for incurable cancers
Regular exercise & better diet lowers cholesterol and can help in preventing cancer
CT scan detects 70% of early-stage lung cancers; NHS England launches pilot screening
Antioxidant compound in green tea improves p53 levels and insights offer new approach to cancer therapies
Prostagram allows easy access and a precise diagnosis of aggressive prostate cancers
Poop to pill: fecal transplants restore healthy gut microbes boosting immunity to fight cancer
Clinical trials in progress for potential targets of cancer and neurodegenerative diseases
Nanoparticles with chemotherapy agent act longer, a potential alternative to cancer surgeries
Customizable nanobots to the cancer type could silence the targeted cancer genes
Relays all information & reports to offer real time solutions to physician problems
Hopefully this test could be available on the NHS later this year - form an orderly queue!
IMTs degraded 1 in 3 cancer cell lines in vitro, and early promise in mice
Reinforce importance of surveillance & preventive measures to tackle cancers
A landmark strategy towards integrating personalised treatments in routine cancer care
Shortening telomere length in cancerous cells will prevent them from dividing
Innovate UK is funding specialists of nanotechnology & bioimaging to cure cancer
Calcium and citrate filled nanoparticles selectively kills cancer cells in mice
Project InnerEye reduces clinicians workload and improves cancer care
Antibody guided microbubbles improves cancer therapy and eliminates toxicity
Consuming high fat diet may weaken the immunity and its ability against cancer
Telomere shortening might be a protective measure to ward off cancers as we age
NHS to offer this test to 165,000 people next year for detecting cancers early
Senolytics to treat cancers - study finds correlation between senescence & survival
Uses CRISPR technology to target and destroy cancer cells
N-LIfT is an allogenic cell therapy which recruits patient's own immune cells against cancers
Metabolites produced during exercise activate cancer-fighting T cells in mouse models
Findings are worrisome as self examination helps in early diagnosis
Ex-Genentech CEO's drug company starts first clinical trial of cancer research
AI provides cheaper and accurate precision for identifying colorectal polyps
A blood test that can detect biomarkers for breast cancer risk and activity
IL-12 self-replicating RNA delivered in lipid nanoparticles (LNPs) shows good results in mice
Marks new era in advancing screening and early diagnosis of cancer technology
New drug could become the best one to target and treat multiple tumours in the future
When improved, could one day promote prevention and early treatment
Able to regress tumor in mice within one to two days, and prevent regrowth
Better studies required to weigh benefits of cancer protection against risk of a GI bleed
Their extreme biology could be key to preventing cancer in humans
CAR-T therapy, a proven approach, now improved to broaden potential targets
Indeed a new precision approach sparing healthy cells
Light, moderate, or vigorous physical activities will make a big difference
It's important to keep funding basic research as no one knows where the answers will lie
A promising anti-cancer immunotherapy approach, and alternative to traditional drugs
Applicable to a wide range of cancer cells, giving hope to the disease sufferers
Allowing developments on tech that will kill cancer based on their genetics
Hopes are up for it to directly help the cancer research community and patients
A safer and more immune-friendly precision-medicine approach for cancer
Demonstrated in a large prospective study involving patients without cancer history
More to look forward as it promises early cancer detection when fine-tuned
How senescence can fuel cancer development and how malignant cells induce senescence
A success in petri dishes and animal models, eyed for potential in tumor drug delivery
Early detection means fewer complications and less financial contributions in the system
AI apps can be inefficient in skin cancer diagnosis, if not properly regulated and certified
Biomarker caused by glycolysis seen in all types of cancer - exciting possibilities
Analyzing cancer DNA in blood can present easier diagnosis and more effective treatments
First CRISPR cancer trial in the world publish its promising findings
This massive study should provide new targets to diagnose and treat all cancers
Made of DNA fragments, nanorobots will be used to locate and destroy cancer cells
Good to see a new approach to tackle cancer, but this is a long way from trials
Acts more on cancer cells compared to normal cells and eliminates them
Preliminary results from Phase 1 trial look promising
Diagnosis with AI combined with pathologist can reduce the risk of misdiagnosis
If clinical trials succeed, it will improve breast cancer screening accuracy and efficiency
If combined they can form the largest database of genetic information on cancer
Improving effectiveness with reduced side effects - fingers crossed for this first-in-person trial
No need to lose weight in fear of breast cancer if you have a healthy weight
ExtraCRAd for cancer immunotherapy tested in vitro and animal model tumor in vivo
High-risk, post-menopausal women should ask their doctor about Anastrozole
Reduces the chances of missing even smallest precancerous lesions
Doesn't have to be vigorous exercises, just moving about is enough
No causal relationship, so those who used permanent dye in the past shouldn't worry over it
Approved for clinical use in Europe - can be done as an outpatient procedure
Only 5% saw their tumours shrink, but may be more successful if used earlier
Technology's advantages in the industry are 99% accuracy, 2 hour detection time, obtainable cost
Needs to identify those who will respond to treatment before starting immunotherapy
When in doubt simply stick to the recommended therapy or ask your doctor
Still at preclinical stage but likely to be harmless for humans as it is based on cowpox
Samples from 800 patients are being tested now for improving the test accuracy
Phase 1 clinical trial starting early 2020
Many drugs for heart diseases are broad-spectrum senolytics as tested in mice
If the right genes to tackle are identified, this could be the cure for all cancers
Trained on over 3 million photos - no human specialist has ever reviewed that many
Does this mean that future therapies to slow down ageing may cause cancers as a side effect?
Olaparib delays cancer growth by months, which means the increased lifespan
UK doctors announce that more than half of the patients can now survive advanced melanoma
Test will be used in a clinical study, if it will get approved, the test will roll out to patients
New drugs present precision medicine, they are based on the genetic make-up of each patient's tumour
By determining the DHX8's structure, scientists could discover new ways of cancer treatment
Donkey's milk has no proven cancer effect - don't make an ass of yourself
If there is an election soon, then maybe consider the parties' health policies as well as Brexit
Detects 50% more early stage lung cancers and being expanded to detect other types
CAR-T therapy gives hope for the children for whom the standard therapies don't work
Removing the protective wall of the tumours can be a promising way for innovative cancer treatments
4x survival rate if EOC is caught early
With all these cancers on the rise, are we acting fast enough?
New approach has been effective in preventing the development of melanoma, treating primary tumours
Better to eat fish than red and processed meat that may increase the cancer risk
"Grab on to life” to get to know your body
Days of receiving one-size-fits-all regimens of chemotherapy and radiation may soon be in the past
Can we win the fight against cancer using viruses to our advantage?
This could be dawn of a new era - cancer treatment without side effects
Nobel Prize winners are involved in the discovery of the ubiquitin system
This might wipe out cervical cancer in the next couple of decades
36‐gene classifiers are known as Prostate Urine Risk (PUR) signatures.
Some lymphoma patients are being completely cured in a way "never been seen before"
Bit of a plug for the Mole Clinic, London, which coincidentally offers a private screening service
Very clever technology – super-accurate blood test without taking a drop of blood
Lowering the levels of HER2 slows cancer cell proliferation and triggers cell death
Systematic approach reveals new targets for drug development
Using iPS cells would be a lot cheaper than personalised immunotherapy
Human trials in a few years time
The virus is able to kill cancer cells, tumour feeding new blood vessel cells and cancer stem cells
Results available in less than a week
More accurate than current methods - we'll hear this a lot with AI in healthcare
Novel mechanisms for attacking cancer cells are always good news
Four times faster increase in pancreatic cancers in the younger generation
Only 266 participants in trial, but big pharma doesn’t pay to test free drugs
Accurate risk estimate only available with a complete set of data for a patient.
Once trained artificial intelligence is almost aways going to be more reliable than humans
It's important to realise the possible serious implications of the symptoms
VOCs in breath captured by mask sent to lab for diagnosis - avoids invasive tests
Allows researchers to better understand tumour structure and examine it from any angle
Even specialist dermatologists can miss melanomas without a dermoscope
Will take only ten minutes to tell you all about your cancers
Dabrafenib and Trametinib are being offered for BRAF-positive melanoma patients
Doesn't seem to harm normal cells unlike telomerase blocking drugs that are too toxic
Nanoparticles reduce drug toxicity and promote cancer cell targeting
NHS establishes a network of specialized centres for DNA analysis for "specialized medicine"
Treatment consist in collecting, in vitro expansion and injection of white blood cells in patients
Increasing numbers of people getting the risk factors wrong.
Dundee University using ultrasound to detect prostate tumours.
Uses the patient’s immune cells as a sort of T-cell training force.
Colorectal cancer is the third leading cause of cancer deaths.
Patients often face delays when they have non-specific symptoms.
According to a study by Cancer Research UK more than 135,500 cases of cancer a year in the UK could be prevented through lifestyle change.
In 2007, Australia began providing free HPV vaccine to girls aged 12-13 years.
Biopsies were taken and grown into miniature 3D cancerous organs in the lab.
Treatment works by stimulating the internal defences of patients to fight their tumours.
Rutgers University has devised a new method for detecting tiny cancerous tumours.
Four in 10 patients with aggressive lymphoma were cancer-free 15 months after treatment.
Uses cancer-killing cells from people with the strongest immune systems.
Researchers looked at tissue samples from people with Barrett’s oesophagus that develop into cancer in around 5% of people.
In many metastasized types of cancer, disseminated tumors grow back despite successful chemotherapy.
Thermotherapy is limited by the damage it causes to healthy tissues.
Small RNA molecules can trigger a mechanism forces cells to commit suicide.
Hyperactive sugar consumption of cancerous cells leads to rapid growth and development of cancer
Genetic test is a faster, less expensive treatment method for men with advanced prostate cancer
Highly targeted form of radiotherapy shapes radiation beams to tumours.
Triple negative breast cancer is (TNBC) tend to exhibit aggressive behaviour and are more likely to spread to another part of the body, becoming incurable.
London start-up launches Car-T clinical trials.
Researchers from Shandong University carried out the study on 1,316 women aged between 25 and 70 from Northern and Eastern China who had recently been diagnosed with breast cancer.
The Sydney-based Melanoma Institute Australia conducted 2 drug trials of new treatments and have proved it successful in preventing melanoma spreading in stage three patients whose tumours had been surgically removed.
Skyler Johnson and his colleagues at Yale School of Medicine in Connecticut say that people who choose alternative medicine over conventional treatment for their cancer are more likely to die from the disease.
Technology will help explain the deadly process of cancer spreading.
Six melanoma patients given an experimental, custom-made, neoantigen vaccine.
Researchers have been trying to find ways to ramp up the immune response to tumours.
Possible to detect tumours 10 years before they become dangerous.
Lessons learnt may be applied by other oncologists in future
Short-term fasting protects healthy cells from cancer fighting drugs
Strong evidence people who are overweight have an increased risk of developing 11 different cancers.
Because the pancreas is deep inside the body and is difficult to image or biopsy, spotting the cancer is hard.
Patient-derived xenografts are tumour samples that are extracted from patients and reimplanted in mice in the same location as in the patient.
Prostate cancer is the most common cancer in British men
Cancer Research UK Cambridge Institute’s programme will map patients’ DNA and RNA to tailor treatment to individuals.
$72,000 raised for high-throughput screening of a library of diverse drugs to find treatments for ‘ALT’ cancers.
347 deaths per year in England could be prevented if all eligible women attended cervical screening.
Three out of four people are unaware being overweight increases the risk of developing 10 different types of cancer.
Time spent overweight or obese seems to have a compounding effect on cancer risk.
Nanoparticulate RNA immunotherapy puts pieces of cancer’s genetic RNA into tiny nanoparticles of fat and injects into the bloodstream.
The cancer moonshot is a $1bn (£710m) injection of cash intended to bring a decade’s worth of advances in just five years.
90% of terminally ill patients treated went into remission.
First patients have their DNA analysed in massive study.
10 days to get a cancer patient’s comprehensive genomic profiling analysis.
Fratricidins — cancer that kills cancer
New study published in Nature concludes only 10-30% of cancers were down to “luck”.
Uses single chemical compound (SiNc-PNP) for both diagnosis and treatment of cancer.
Study of 14,000 people with cancer in gastrointestinal tract.
DNA mutation of individual tumour analysed when removed. Regular tests then searched for unique DNA profile in patient’s blood to detect possible relapse.
50 of the 85 chemicals shown to disrupt cells such as interfering with the repair of damaged genes which is a key layer of cancer defense. Study by Halifax Project team of nearly 200 scientists.
Study finds prostate cancer is not one disease but several – enabling personalised treatments using existing cancer drugs.
Overall, patients who received the drug lived 10 months longer, but for patients where the cancer had already spread beyond the pelvis, the increase in life expectancy was 22 months.
An international team of scientists has been able to recreate a patient's gut using cancer cells
cancer hijacks telomeres, which prevent DNA damage, to flourish in the body.
Implantable device could allow doctors to test cancer drugs in patients before prescribing chemotherapy.
Results from first-in-human study in lymphoma patients confirm feasibility for toxicity-sparing assessment of drug efficacy in cancer patients.
Could replace invasive biopsies in diagnosis
Very fit men in their late 40s are less likely to get lung cancer and colorectal cancer than unfit men.
Analysis suggests that one in two people in the UK will be diagnosed with cancer at some point in their lives.
Patient’s living tumor implanted in mice – test multiple cancer drugs to find the most effective one
Eating tomatoes may lower the risk of prostate cancer, research suggests.
Naked mole rats are subterranean rodents that have never been known to get cancer.
Researchers have developed a highly sensitive exhaled-breath sensor.