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Exercise could boost immune cells to help fight cancers

Metabolites produced during exercise activate cancer-fighting T cells in mouse models

28-Oct-2020

Key points from article :

Exercise might prevent some types of cancer from growing and spreading.

Results are based on mice models, but preliminary tests in humans also suggest the same.

Exercise is linked to a lower risk of bladder, breast, colon, kidney and stomach cancer.

Cancerous mice that regularly exercised showed slower cancer growth and better rates of survival than the ones who didn't.

Elevated levels of metabolites after exercise, like lactate, could 'feed' T cells to improve their effectiveness against tumours.

Results were also tested in 8 healthy male participants which showed similar results.

"..this may contribute to a deeper understanding of how our lifestyle impacts our immune system and inform the development of new immunotherapies against cancer," says Rundqvist.

Study by Karolinska Institutet published in eLife.

Mentioned in this article:

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eLife Sciences

Non-profit journal publishing work in all areas of biology and medicine

Helene Rundqvist

Senior researcher at the Department of Laboratory Medicine, Karolinska Institutet

Karolinska Institutet

Public Medical university

Topics mentioned on this page:
Exercise, Cancer