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New blood test detects cancer 4 years before symptoms appear

21-Jul-2020

Key points from article :

A blood test can pick up cancers up to four years before symptoms appear.

Called PanSeer, detects cancer in 95% of individuals without symptoms but later receive a diagnosis.

Based on screening particular regions of DNA found in blood plasma for tags or methyl groups.

Machine learning algorithm used to verify if the DNA found in the blood was shed by tumours.

95% of participants who were not diagnosed with cancer but later went on to develop the disease.

The test correctly identified those without cancer 96% of the time.

One limitation is that is cannot identify which type of cancer the person has.

“The PanSeer test has achieved encouraging initial results."

Test may be able to detect cancer in blood samples taken years before diagnosis.

"But these are early results that now need to be validated in larger studies."

Researchers from China, published in Nature Communications.

When improved, could one day promote prevention and early treatment

Mentioned in this article:

Health Organisation
Cleveland Clinic
- American academic medical center based in Cleveland.
Health Professional
Eric Klein
- Urologist in Cleveland, Ohio
Journal
Nature Communications
- Journal covering all topics in physics, chemistry, and biology.
Product
PanSeer
- Blood-based cancer screening test, Singlera Oncology
Academic
Samantha Harrison
- Senior early diagnosis manager at Cancer Research UK