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New blood test detects cancer 4 years before symptoms appear

When improved, could one day promote prevention and early treatment

21-Jul-2020

Key points from article :

A blood test can pick up cancers up to four years before symptoms appear.

Called PanSeer, detects cancer in 95% of individuals without symptoms but later receive a diagnosis.

Based on screening particular regions of DNA found in blood plasma for tags or methyl groups.

Machine learning algorithm used to verify if the DNA found in the blood was shed by tumours.

95% of participants who were not diagnosed with cancer but later went on to develop the disease.

The test correctly identified those without cancer 96% of the time.

One limitation is that is cannot identify which type of cancer the person has.

“The PanSeer test has achieved encouraging initial results."

Test may be able to detect cancer in blood samples taken years before diagnosis.

"But these are early results that now need to be validated in larger studies."

Researchers from China, published in Nature Communications.

Mentioned in this article:

Click on resource name for more details.

Cancer Research UK

Independent cancer charity focused on saving lives through research, influence and information

Cleveland Clinic

American academic medical center based in Cleveland.

Eric Klein

Urologist in Cleveland, Ohio

Nature Communications

Journal covering all topics in physics, chemistry, and biology

PanSeer

Blood-based cancer screening test, Singlera Oncology

Samantha Harrison

Head of Strategic Evidence and ICBP Lead at Cancer Research UK (CRUK)

Topics mentioned on this page:
Cancer, Diagnostics