Whole-cancer genome analysis to revolutionize cancer treatment

05-Feb-2020
KEY POINTS FROM ARTICLE:

Whole genetic code of 2,658 cancers were analysed in this landmark study.
It took more than a thousand scientists, 22 scientific journal papers to describe cancer complexity.
Project found average of 4-5 fundamental mutations that drive human cancer's growth.
Potential weak-spots can be exploited with treatments that attack these "driver mutations".
Researchers developed a way of "carbon dating" mutations.
First timelines of genetic mutations across the spectrum of cancer types, established.
Research by the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Consortium, published in Nature.

This massive study should provide new targets to diagnose and treat all cancers

Mentioned in this article:

Institute International Cancer Genome Consortium (ICGC) - Voluntary scientific organization on cancer and genomic research

Institute National Cancer Institute (NCI) - Institute for cancer research.

Journal Nature

Research Pan-Cancer Analysis of Whole Genomes Consortium - ICGC/TCGA International collaboration for cancer research

Research The Cancer Genome Atlas (TCGA) - Landmark cancer genomics program

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