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Tiny spheres could deliver cancer drugs with no side effects

Antibody guided microbubbles improves cancer therapy and eliminates toxicity

09-Dec-2020

Key points from article :

Microbubbles are small manufactured spheres half the size of a red blood cell.

Scientists believe they can be used to transport drugs to highly specific locations within the body.

Antibodies attached to the microbubbles are attracted to the growth hormone found around cancer cells.

Then microbubbles became concentrated at the site of the tumour.

An ultrasound device was used to burst open the microbubbles, releasing anti-cancer agent at tumour site.

“Microbubbles allow us to use powerful drugs with precision, that reduces the risk of damaging healthy cells.” - Nicola Ingram, lead author.

Scientists were able to slow cancer growth with a much smaller drug dose.

“Efficacy of drug delivery is substantially improved..." Stephen Evans, co author.

Mext stage of the research is to look at using microbubbles to develop targeted, triggered, delivery systems in patients.

Research by University of Leeds published in Theranostics.

Mentioned in this article:

Click on resource name for more details.

Nicola Ingram

Senior Research Fellow at University of Leeds

Stephen Evans

Professor at University of Leeds

Theranostics

Online open access journal about diagnostics and therapeutics

University of Leeds

University for research power.

Topics mentioned on this page:
Nanomedicines, Cancer