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A wonder drug for the treatment of advanced bowel cancer patients

Experimental gene therapy shrunk tumor size by 50% within three months

28-Mar-2022

Key points from article :

A cancer patient has hailed "a wonder drug" after getting a treatment targeting a gene that controls how the disease grows.

Women with stage 4 bowel cancer and metastatic lung cancer participated in early-phase clinical trials which used targeted therapies.

Previously, three types of chemotherapy had failed, and she lost appetite and weight.

According to the Christie NHS trust, she was climbing stairs with no effort within hours of trialling a new drug.

After three months of the treatment, size of tumors was halved and she looked much healthier.

Matthew Krebs, medical oncologist said "promising for a drug early in its development directed at KRAS mutation that has historically been very difficult to treat".

"It targets only a specific sub-type of KRAS mutation, and a similar drug has already been approved for patients with lung cancer."

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Matthew Krebs

Clinical Senior Lecturer in Experimental Cancer Medicine and Honorary Consultant in Medical Oncology

The Christie NHS Foundation Trust

NHS Foundation Trust in Manchester

Topics mentioned on this page:
Cancer