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Mechanical nanosurgery, a novel treatment option for glioblastoma


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Scientists developed a new methodology termed "mechanical nanosurgery" to battle against glioblastoma.

Carbon nanotubes (CNTs) loaded with magnetic iron nanoparticles and labelled an antibody targeting CD44 (found in tumors). 

After injecting into the brain region with drug-resistant glioblastoma cells, the CNTs rotate under the influence of a magnetic field.

Disruption of cell structures effectively kills off the cancerous cells, leading to enhanced survival rates in treated mice.

Primarily, the technique could serve as a lifeline for patients who developed resistance to traditional therapies.

The methodology could be customized to target different types of cancers.

Challenges are regulatory requirements for human trials, high research & development costs, efficacy, and potential risk to healthy cells.

There is no clear timeline for when this treatment might be ready for human trials.

With continued research and adequate funding, this innovation could develop a new era of cancer treatment.

Research led by Yu Sun from University of Toronto, published in the journal Science Advances.

Magnetically guided nanotubes effectively killed cancer cells in mice

Mentioned in this article:

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Science Advances

Journal that publishes original research and reviews in all disciplines of science

University of Toronto

Public research university located in Toronto

Yu Sun

Professor of Mechanical Engineering and Director of University of Toronto Robotics Institute at University of Toronto.

Mechanical nanosurgery, a novel treatment option for glioblastoma