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Diet quality linked to slower prostate cancer progression

Study suggests a healthy diet may reduce the risk of cancer advancing during active surveillance

17-Oct-2024

Key points from article :

A new study published in JAMA Oncology suggests that a healthy diet may help men with low-grade prostate cancer reduce the likelihood of cancer progression. Conducted by Johns Hopkins Medicine researchers, this study is among the first to provide scientific evidence linking high-quality diet adherence to a slower progression of prostate cancer among men undergoing active surveillance. Active surveillance is a strategy for low-risk cancer patients who avoid immediate treatment, opting instead for regular monitoring to minimize side effects.

Led by Dr. Bruce Trock, the team studied 886 men diagnosed with grade group 1 prostate cancer. Participants completed dietary questionnaires, and their diets were scored based on the Healthy Eating Index (HEI), which evaluates how well a diet aligns with the USDA’s dietary guidelines. Men with higher HEI scores showed a statistically significant reduction in the progression of their cancer, with a 15% reduction in the risk of advancing to grade group 2 and a 30% reduction for grade group 3.

Researchers also explored the potential link between diet-related inflammation and cancer progression, though they found no strong correlation. These findings offer promising insights for men on active surveillance who are motivated to adopt dietary changes. However, further studies with more diverse populations are needed to confirm these associations and develop concrete dietary recommendations.

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Bruce Trock

A professor of oncology at the Johns Hopkins University School of Medicine

JAMA Oncology

International peer-reviewed journal and the definitive journal for scientists, clinicians, and trainees in the field of oncology

Johns Hopkins Medicine

Governing structure for Johns Hopkins University

Topics mentioned on this page:
Cancer, Diet and Nutrition
Diet quality linked to slower prostate cancer progression