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New missile-like radioactive therapy treats prostate cancer

Precisely targeted therapy shrank tumours and extends life by 38% in men

03-Jun-2021

Key points from article :

New high-tech drug treatment for prostate cancer can keep patients alive and healthy for longer, a new phase III trial reports.

The search and destroy treatment could shrink tumours while leaving healthy cells unharmed.

Uses a homing device to seek out cancers by detecting the prostate-specific membrane antigen (PSMA) on the surface of cancer cells.

Clinical trial involved 831 participants with PSMA-positive advanced prostate cancer.

Adding 177Lu-PSMA-617 to standard care extended patients’ lives by 4 months.

Men were 38% less likely to die during the 20.9-month follow-up.

“This new treatment acts like a guided missile seeking out cancer cells," - Johann de Bono, study co-author.

“A smarter, kinder treatment...while reducing the risk of side effects," - Paul Workman, Chief Executive of ICR.

Research by ICR, Royal Marsden NHS Foundation Trust, and Memorial Sloan Kettering Cancer Center, to be presented at the ASCO.

Mentioned in this article:

Click on resource name for more details.

American Society of Clinical Oncology

Non-profit organization for advancing cancer research

Johann de Bono

Consultant at the Institute of Cancer Research

Memorial Sloan Kettering Cancer Center

Cancer treatment and research institution in New York City

Paul Workman

Chief Executive and President of The Institute of Cancer Research.

Royal Marsden NHS Foundation Trust

Hospital dedicated to cancer diagnosis, treatment, research and education.

The Institute of Cancer Research (ICR)

One of the world’s most influential cancer research organizations

Topics mentioned on this page:
Cancer