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Genomes of 13,000 UK patients decoded, marking the dawn of precision oncology

Provides oncologists with a precise tumor genetic map for selecting treatments

11-Jan-2024

Key points from article :

A major UK study analyzed the entire genetic code of 13,000 cancer patients to personalize treatment.

Combining clinical data with DNA, doctors tailored drugs and avoided ineffective or harmful ones.

Over 90% of brain tumors and most bowel and lung cancers showed genetic changes guiding surgery or specific treatments.

In sarcomas, genetic variations revealed subtypes, helping choose the right therapy.

10% of ovarian cancers were likely inherited, providing insights for family members.

This research, published in Nature Medicine,  paves the way for incorporating whole-genome sequencing into routine cancer care across the UK.

The study was carried out by researchers at Genomins England.

Mentioned in this article:

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Genomics England

Genomics England was set up to deliver the 100,000 Genomes Project

Nature Medicine

Scientific Journal providing information from all areas of medicine

Topics mentioned on this page:
Precision Medicine, Cancer
Genomes of 13,000 UK patients decoded, marking the dawn of precision oncology