Stem cell breakthrough restores sight in world-first treatment
Nature - 08-Nov-2024Reprogrammed cells from healthy donors give hope to patients with severe corneal damage
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Reprogrammed cells from healthy donors give hope to patients with severe corneal damage
Potential risks like DNA damage from space radiation require further study
Unlocking the secrets of longevity with induced pluripotent stem cells
Clock.bio secures funding to explore genetic pathways for enhancing healthspan
A successful retinal transplant in a monkey shows promise for treating vision loss
Mesenchymal stem cells may revolutionize healthcare by combating inflammation and ageing
A pioneering trial reveals the potential of reprogrammed stem cells to reverse type 1 diabetes
The startup leverages its TFome™ platform for rapid and efficient iPSC programming
This lab-grown blood could solve donor shortages and help with frequent transfusions
Cutting-edge AI and laser technology will scale production of personalized regenerative medicines
New stem cell breakthrough offers personalized cancer treatment with less rejection risk
Ancient genes in sea anemones offer insights into ageing and regeneration
75% of participants experienced clinical improvement in both pain and function
No severe issues came from the therapy itself, just the procedure or immunosuppression
New phase 3b study aims to resolve manufacturing challenges and support regulatory approval
This opens up new possibilities for regenerative medicine and tissue repair
Canadian company secures $8M to unlock future regenerative therapies through cryopreservation
This discovery could have important implications for understanding healthy ageing processes
Successful monkey trials bring hope for safer regeneration therapies in humans
Potential tool in boosting immune function and combating the effects of ageing
Machine learning reveals widespread decline in stem cell potency with age
The drug targets the lungs and activates stem cells
Specialized protocol aims to address early-stage ALS and advance regulatory approval efforts
Experimental stem cell therapy offers hope for spinal cord injury patients
The discovery reveals the body's potential for self-rejuvenation
Potential treatment approach to boost immunity and fight disease in older adults
This innovative therapy uses a collagen microgel scaffold to improve stem cell survival
Bodies of younger people could potentially rejuvenate older transplanted cells
Genetically-modified stem cells avoid immune rejection, paving way for universal therapies for everyone
Hydrogels mimicking cellular niche could revolutionize the treatment of brain & spinal injuries
This low-cost, scalable device could revolutionise spinal cord injuries treatment
Genetically modified stem cells bypass immune rejection, paving way for universal therapies
Focused on regenerative treatments for feline gingivitis, canine arthritis, and more
Company's EA 2351 paves the way for potential vision restoration in patients
Aspen Neuroscience's ANPD001 aims to replace lost neurons and improve motor function
Enrollment paused, but $1.5 million secured from new partnership
A personalised approach to healing the brain and restoring lost function
Offers hope for aHSCT as the future standard of care for 130,000 UK MS patients
Small clinical trial shows treatment can improve breathing and quality of life
Stem cell-based embryo models could lead to new treatments for infertility
Urolithin A rejuvenated blood stem cells in mice, boosting infection defence
Multistem aims to boost organ preservation and transplant success
Liesel the gorilla is now walking again after receiving Stem CellX treatment
Funding will be used to test the patch in geographic atrophy patients in phase 2b trial
A breakthrough approach to make enamel by mirroring gene pathways in natural tooth formation
Details magic of converting stem cells to any cell type and transplanting them to treat age-related conditions
Its polymer-supplemented culture system enables cell expansion without harmful mutations
Unregulated clinics worldwide are offering unproven, dangerous treatments, exploiting regulatory loopholes and misleading desperate patients
Multistem combats inflammation to improve trauma recovery
Lab grown tooth could soon become a reality - provides hope against painful root canal treatments
Bemdaneprocel shows positive phase I results, advances to Phase II trial in early 2024
Combination of factors that rejuvenate stem cells holds promise for aging and muscle-wasting diseases
Groundbreaking method poised to revolutionise regenerative medicine
Therapeutics to boost regulation of protein homeostasis may be beneficial across multiple organs and pathologies
Fully automated Intelligent Cell Processing System to manufacture potentially life-saving treatments
A new weapon that could give doctors an entirely new way to treat heart failure
Higher levels of glutathione better at muscle repair while low levels of the same are bad at it
MSCExos shown to improve osteoporosis by promoting osteoclast cell proliferation and formation of blood vessels
Arthritis drug named anakinra found to reverse ageing effects in blood in mice
This one-off treatment could nullify the complications that you get with chronic medications
This approach did not kill the senescent cells instead, it was senomorphic
Kizoo is focused on rejuvenation biotech so it must see potential in normalizing CDC42 activity
Whole genome sequencing-necessary to validate Stem cell lines used for therapy
Endogena's gene-independent treatment has shown advantages in retinitis pigmentosa
ECM proteins play significant roles in hPSC adhesion, growth & cardiac differentiation
Stem cells in human urine have major advantages over stem cells from other sources
Treatments targeting faster-growing stem cells & low-quality blood cells can promote healthy ageing
Could eventually lead to treatments that reinvigorate immune cell production
Multistem shows promise in secondary measures but misses key endpoint
Combined approach surprisingly eliminated the negative effects of individual treatments
Lomecel-B targets homing and microglia recruitment rather than differentiation
Treatment was successful in mice, and now gears up to treat paralyzed humans
Painless bone regeneration with a faster, easier and effective approach
Both are leading first generation longevity treatments - even better if they strengthen each other
Fast, cheap and plentiful iPSCs will be needed for clinical trials and new treatments
Noninvasive imaging technology used to observe aging on the cellular level
Many studies underlined beneficial effects of calorie restriction in various tissues of mice
Challenges of mass producing stem cells and how 3 companies are attempting to overcome them
Short-term treatment of mesenchymal cells with acetate resulted to enhanced stem cell
Reduced inflammation & bone damage in mice; relieves patients from their regular use of injections
Tendons regain their original healthy condition within 2 months of therapy in sheep
Reliable and safe generation of a novel stem cell-based therapy for dementia
Improvement seen in blood stem cells of mice and humans against stress and ageing
Molecular level benefits observed (inflammation, senescence) as well as physical ones
Evidence of cryptic transcription in older cells offers new strategies for longevity
Potential stem cell treatment for age-related diseases, if succeded in human trials
Slowing down natural ageing process of pituitary glands with stem cells
Need for stem cell intervention for patients diagnosed with T2DM
Funding four bold projects to improve health care outcomes for degenerative diseases
Will be looking to run a human clinical trial in the next few years
Cell therapy repairs brain damage from dementia and stroke in mice, soon to begin human trials
For the first time, cultured retinal cells transplanted & survived in the eyes of mice for a year
Abl1 gene as a potential drug target improved stem cell rejuvenation in aged mice
Givinostat induces stem cells to produce muscle making cells - promising therapy for age-related muscle loss
Balance in cell divisions control regenerative capabilities of hair follicle stem cells
SMS cells play a significant role in lung repair and regeneration, and other inflammatory diseases
A potential application in humans for Parkinson's with nerve grafts made from own stem cells
Macrophages and stem cell interaction promotes muscle repair in zebrafish and mice models
Biotech startup to make stem-cell based therapies to extend and save lives
Reprogrammed stem cells treated Parkinson's in rats; initiating clinical trials soon
Let's hope other stem cell treatments are closer than 15 years away
Insights on this unique strategy could have breakthrough treatments for ageing and many diseases
Greying of hair is irrespective of age and gender; Scientists work on stem cells
Will help in kidney tissue engineering and regenerative medicine
Control neurogenesis by causing nerve stem cells to divide & thus help brain adapt in mice
First ever drug guided stem cell therapy in the field of regenerative medicine
Semi-automating tissue differentiation makes artificial tissues at a faster rate
New generation companies develop novel cell therapies using stem cells
From coffee enemas to pants blocking EMF radiation - his routine is straight out of a sci fi movie
Now we can produce large quantities of human pluripotent stem cells
Lifespan of hair follicle stem cells can be prolonged by changing their metabolic state
Bioengineered minimally invasive shielded stem cells reduces heart attack damage
One should still consume adequate nutrition while reducing calorie intake
NRG1 treatment boosted activity of gut stem cells - could help protect gut during chemotherapy
Exosomes will help reduce complications of using living stem cells for brain repair
UK-based startup reprogramming stem cells to generate new cell therapies
Findings open up new possibilities for personalized regenerative medicine
Major step towards treating baldness, skin diseases, also wounds and scarring
Japan's Pharmaceutical and Medical Devices Agency gives the green light for human trials
Its anti-ageing action through skin deep regeneration succesfully achieved
Transplanting glial cells in worked in mouse models affected with MS
Clinical trial in androgenetic alopecia patients show an increase in hair density, thickness
These mouse models can be used to study about diseases such as malaria and COVID-19
Study and procedure represent a milestone in personalized medicine for Parkinson's
New therapeutic personalized strategy could bring back movement to those suffering
Able to recover from induced surgical ischameia in hind legs of mice
Evident in old mice, this exercise can also accelerate muscle tissue repair
New possibility on restoring injured neural circuitry in humans after stroke
Stem cell transplantation gives hope to humans affected by stroke
May cause serious adverse effects if stem cells over attack normal lung cells
Stanford University researchers spin out Turn Biotechnologies to develop therapies using OSKMLN
How long will it take until this can be applied to human cells inside the body?
Scientists created stem cells from supercentenarian for the first time, calling it "super sauce"
This arrival of a more efficient stem cell type has high impact for regenerative medicine
A small study, but a big impact on the 7 participants who all recovered quickly
A success in mice trial, now to move forward to larger animals then human clinical trials
Evidence of cellular age reversal demonstrated in this gateway research
Stimulation the production of stem cells is in direct comparison with the healing speed
Modulating your stress levels will help you prevent many problems, including your hair colour
Further research will give us a better understanding about stem cells in general
Researchers able to teach old mice new tricks ;)
Preliminary results from Phase 1 trial look promising
Patient-derived induced pluripotent stem cells to replace dead retinal cells
US companies received a warning from the FDA for selling stem cell products without approval
New reprogramming technology could provide an alternate source of material needed for therapies
Gene editing and stem therapy together could bring far superior treatment methods
Functional organs from stem cells possible through machine learning and gene-editing
May only be a few years away from implementing induced tissue regeneration in humans
Creating totipotent stem cells opens ways for revolutionary findings in regenerative medicine
Donors cells were adult skin cells, which have reprogrammed into an embryonic-like state
Pluripotent cells are like a black box, but they can open new doors for regenerative medicine
Used brain stem cells of young and old rats for this research
This will be the solution to post heart attack complications
Just one pathway out of many that could improve tissue rejuvenation
Ongoing clinical trials for heart patients with cellular therapy to cure damaged heart muscles
"Pumping" patch could help repair the damage caused by a heart attack
Using droplets of globose basal cells made able to restore the sense of smell of the mice
Creating beating cells and blood vessels that could treat heart attack victims
Discovery could revolutionise treatment for vascular and diabetes-related cardiovascular diseases
Supplement has a real physical health impact too = reduced inflammation
Turn.bio testing new in vivo therapy - good results for sarcopenia in mice
Nearly 1,000 clinics selling unregulated treatments in the US
Rejuvenation human trials (cell reprogramming) possible in next 2 years
Could lead to off-the-shelf stem cell therapies
Able to regenerate ageing immune system, and reduce cost of immunotherapy
Reducing frailty allows people to keep moving and break the negative feedback cycle of aging.
A man in his 50s is the first of seven patients to receive the experimental therapy
Implantation of induced stem cells in brains with Parkinson’s disease is showing promising results in monkeys
Growing new organs from patient's own cells would slash the wait times for organ transplants
Hematopoietic stem cell therapy allowed a man with multiple sclerosis to walk again for the first time in 10 years
Direct-to-costumer marketing of stem cell interventions tend to minimize risk and make bold claims without scientific support
A company is looking to start trials for induced stem cells to fight graft vs host disease
A topical solution converts cells from wounds into skin to repair tissue without scarring
Researchers plan to implant induced stem cell-sheets on the heart to regenerate injured areas
There is a risk of developing brain tumours according to some experts
Harvesting stem cells from teeth may be the key to make treatments more affordable
Confocal microscopy was used to record stem cells repairing a severe injury in Zebra fish
FDA seeking court orders to stop two stem cell clinics.
AstraZeneca will develop cardiovascular and catheter-based therapies.
Forever Labs extracts and stores young adults' stem cells.
Will produce cells derived from iPS cells for commercial applications.
Major step towards curing age-related macular degeneration.
Celularity is a spinout from Celgene, a global biopharmaceutical company.
Multiple Sclerosis (MS) patient regains ability to walk with stem cell therapy.
“Virgin birth” stem cells come from unfertilised eggs.
Natural stem cell loss in hypothalamus was closely correlated with ageing changes.
Mesenchymal stem cells grown and engineered for transplantation with minimal risk.
Researchers create Expanded Potential Stem Cells (EPSCs) in mice.
Stem cell research, or regenerative medicine, has great potential and has already delivered some breakthroughs, but its future is threatened by poor science, unrealistic hopes, unclear funding models and unscrupulous private clinics, they say in the Lance
The F.D.A. reported actions against two large stem cell clinics and a biotech company calling them “unscrupulous actors” in regenerative medicine.
The number and therapeutic quality of our stem cells diminishes with age.
Implanted stem cells that make fresh neurons in the brain.
With aging the immune response becomes deregulated and inflammation becomes excessive.
Interesting interview with Peter Diamandis - founder of the X Prize Foundation and Singularity University. Many billionaires are getting annual placenta stem cell transfusions - and feel better for it. Placental mesenchymal stem cells (MSCs) do not t
Patient had no cartilage in wrist so joint was bone-on-bone and constantly inflamed.
One team reprogrammed skin cell derived iPS cells with seven transcription factors.
Synthetic embryos could be assembled from stem cells that can organize themselves into embryolike structures.
Adult stem cells collected directly from human fat are more stable than other cells.
iPSCs treatments have been slowed by concerns that these cells are prone to increased numbers of genetic mutations.
End-stage retinal degeneration (e.g. age-related macular degeneration, retinitis pigmentosais) is the most common cause of irreversible vision loss and blindness in older adults.
Scientists from Penn State have uncovered the cellular mechanisms that control the programming of the stem cells.
Previous attempts resulted in younger cells but the mice developed tumours.
Therapies that deliver fresh new stem cell populations will take up the work of lost cells, e.g. muscle cells in order to reduce frailty.
Desperate patients are ready to do everything to access to new treatments.
Gladstone Institutes has used chemicals to transform human skin cells into heart cells.
New filling stimulates stem cells to encourage the growth of dentin — the bony material that makes up the majority of the tooth.
Able to regenerate any tissue damaged by injury, disease, or aging.
Direct reprogramming signals a cell to morph straight into another cell type.
Therapies available in clinics vary in type and quality of cells used.
Able to print extremely delicate iPS cells in three dimensions without damaging their biological functions.
Monthly intravenous stem cells transplantations extend life span of rats by 31.3%.
His discovery fast tracked the field of regenerative medicine by many miles