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Musculoskeletal System News Archive

Gut bacteria and blood molecules offer clues to why grip strength weakens with age

Live Forever Club - 21-Feb-2024

Research opens doors for future interventions to prevent muscle loss

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Rejuvenate Biomed's potential drug candidate combats sarcopenia in older adults

Rejuvenate Biomed - 21-Feb-2024

Phase 1b trial shows RJx-01's ability to improve muscle strength, function, and fatigue resistance

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Rejuvenate Bio partners with animal company to develop gene therapy for canine osteoarthritis

Biospace - 14-Feb-2024

Single dose injection targets root causes, offering long-term relief & improved quality of life

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Daily choices like exercise, diet, and even how you breathe affect your mitochondria

Live Forever Club - 09-Feb-2024

Making small changes to your lifestyle can have a significant impact on health

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A new medicine called JUV-161 might help people with DM1, a rare muscle disease

Business Wire - 23-Jan-2024

It improved muscles and slowed down the disease in animals

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Astronauts and the elderly might get special shots to keep their bones strong

Medical Xpress - 22-Jan-2024

The potential for human trials starting by 2025 suggests rapid progress

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Activating SIRT6, a DNA repair protein, reduces damage in ageing cells

Live Forever Club - 01-Jan-2024

SIRT6 activation may be a potential therapeutic target for osteoarthritis

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Evolved.Bio pioneers a scaffold-free method to regenerate muscle tissue

Phys.org - 10-Nov-2023

Offering hope for individuals with significant muscle damage

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Eating less, living longer: the positive effects of calorie restriction

International Institute on Ageing (INIA) - 16-Oct-2023

Modest calorie reduction can activate genes for healthy ageing

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Stem cell therapy gives arthritic gorilla new lease of life

Interesting Engineering - 03-Sep-2023

Liesel the gorilla is now walking again after receiving Stem CellX treatment

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Vegetarian diet may increase hip fracture risk by 50%

Medical News Today - 08-Aug-2023

Well-balanced diet with plenty of protein and key nutrients could reduce risk of bone fractures

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Signalling pathways in aged cells found to impair the ability to repair and regenerate muscle cells

Independent - 07-Aug-2023

Study results offer insights on future drug discovery for disease related to muscle ageing

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Metformin may minimize muscle loss in extended periods of bed rest

Lifespan.io (LEAF) - 24-Jul-2023

Improvements seen in muscle size and collagen deposits in older people with atrophy

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Revitalizing ageing stem cells: Unveiling the key to lasting youthfulness

Lifespan.io (LEAF) - 05-Jun-2023

Combination of factors that rejuvenate stem cells holds promise for aging and muscle-wasting diseases

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Revolutionary bio-inspired molecules accelerate bone healing: a breakthrough for regenerative medicine

TU Dresden (University of Technology) - 28-Apr-2023

Novel molecules enhance bone regeneration in mice by 50%, paving the way for treatments for bone fractures and related conditions

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AKL Therapeutics’ investigational oral senotherapeutics drug APPA beneficial for osteoarthritis

Longevity Technology - 20-Mar-2023

Senescent cells have become one of the most promising targets for healthy aging research

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Restoring glutathione -potential therapy could prevent old impaired stem cells from ever developing

UCLA Health - 27-Feb-2023

Higher levels of glutathione better at muscle repair while low levels of the same are bad at it

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Exploring mesenchymal stem cell derived exosomal therapy as intervertebral disc degeneration cure

Live Forever Club - 08-Feb-2023

MSCExos shown to improve osteoporosis by promoting osteoclast cell proliferation and formation of blood vessels

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Phase 2 clinical trial of lead drug candidate MYMD-1- a therapy for delaying aging

Business Wire - 26-Jul-2022

Sarcopenia drug trial shows no evidence of toxicity or safety issues

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Urolithin A can increase mitochondrial health in living joint tissue and improved mobility

Business Wire - 07-Jul-2022

Mitopure can improve mitochondrial health and counteract age-related muscle function decline

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Sarconeos BIO101 in development for the treatment of Sarcopenia by Biophytis

Yahoo! finance - 27-Jun-2022

SARA-INT Phase 2 study and SARA Phase 3 study milestones in developing sarconeos

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Scientists built a functional human tendon using 3D cryobioprinting

3D Printing Industry - 07-Feb-2022

A breakthrough technique to print complex tissues that can be stored for later use

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A natural cholesterol metabolite with senolytic effect in mice and humans

Buck Institute - 02-Feb-2022

New class of senotherapeutic drugs that could possibly target various diseases and ageing

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Senolytics promotes wound healing in the aged but not in young mice

Lifespan.io (LEAF) - 22-Dec-2021

Dasatinib plus quercetin slow down muscle regeneration in young mice

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MyMD Pharmaceuticals begins phase 2 trial of TNF-inhibitor in January 2022

Longevity Technology - 14-Dec-2021

Potential oral treatment to prevent sarcopenia and frailty, and extend healthy lifespan

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Valuable insight into the influence of age-associated humoral factors

Genetic Engineering & Biotechnology News (GEN) - 07-Dec-2021

An injection of extracellular vesicles improve muscle regeneration

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A powerful platform to facilitate rehabilitation and musculoskeletal diseases

Medgadget - 24-Nov-2021

Thin, wireless, battery-free and multimodal musculoskeletal biointerfaces

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Senolytic cocktail reduces age-related spinal disc degeneration in mice

Lifespan.io (LEAF) - 21-Sep-2021

Dasatinib and quercetin combo preserves spinal discs to target age-related back pain

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A single protein reversed senescence in skeletal muscle cells

University at Buffalo - 17-Sep-2021

NANOG targets multiple ageing mechanisms - insights may help develop new therapies for age-related disorders

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Role of Neuromuscular junction in ageing and neuro muscular diseases

Fight Aging! - 17-Aug-2021

Neuromuscular junction: A potential therapeutic target in neuromuscular injury

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Safer and faster treatment of tendon injuries with stem-cell fat grafts

Genetic Engineering & Biotechnology News (GEN) - 17-Aug-2021

Tendons regain their original healthy condition within 2 months of therapy in sheep

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Skeletal stem cells delay bone healing and foster inflammageing in older people

Medical Xpress - 12-Aug-2021

Treating with BMP2 and Csf1 antagonist in mice restored youthfulness to the aged skeletal system

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Clearing out aged cells with senolytics can relieve jaw pain

University of Connecticut (UConn) - 07-Jul-2021

Senolytics for cartilage and bone regeneration in jaw joints, proven effective in mice

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Zoledronate - accidental discovery of drug use for life extension

Lifespan.io (LEAF) - 30-Jun-2021

Too early to tell whether off-patent drug's effects in fruit flies will be seen in humans

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Returning function to paralysed upper limbs is the primary goal of Orthocell trial

The Market Herald - 21-Jun-2021

Peripheral nerve repair could benefit 3 million patients every year

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Natural compound may help treat intervertebral disc degeneration

Lifespan.io (LEAF) - 12-May-2021

DHE slowed senescence in intervertebral discs of mice; but its use in anti-aging is still questionable

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Low magnitude vibration to prevent/delay age-related bone loss in rats

Lifespan.io (LEAF) - 05-May-2021

Vibration treatment eliminates senescence of bone cells - may not be applicable to other tissues

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Klotho protein reversed muscle ageing in old, but not older mice

eLife Sciences - 20-Apr-2021

Potential future treatment strategy to prevent sarcopenia when supplemented at a young age

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Supplementation with nicotinamide riboside slows age-related bone loss

Fight Aging! - 14-Apr-2021

Long-term use of this supplement boosts NAD+ levels, lowering the risk of osteoporosis in mice

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A man-made molecule that helps repair and regenerate muscle tissue

EurekAlert! - 23-Mar-2021

Givinostat induces stem cells to produce muscle making cells - promising therapy for age-related muscle loss

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Stretchable bioelectronics with silver hydrogel composite

Medgadget - 15-Mar-2021

Electrically conductive, flexible hydrogels to open the door for wearable electronics and soft robots

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Richard Ljuhar sheds light on AI-driven ImageBiopsy lab

Medical Expo - 10-Mar-2021

Highlights the diagnostic accuracy of musculoskeletal diseases using AI processed medical imaging

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Single gene therapy injection halts spinal muscular atrophy

BBC - 08-Mar-2021

Becomes most expensive drug ever approved for the NHS - but no lifetime costs

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Rejuvenate Biomed raises 3.2 million euros for anti-ageing drugs

PharmiWeb.com - 02-Mar-2021

Accelerates clinical trial plans for its lead candidate Rlx-01 targeting age-related muscle failure

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Genetically engineered cartilage combats inflammatory arthritis

National Institute on Aging (NIA) - 24-Feb-2021

Engineered cells produce anti-inflammatory drug that helps reduce stress-related cartilage damage

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Artificial muscles in regeneration of damaged skeletal muscle

Science Daily - 21-Feb-2021

Hybrid constructs help regrow muscle tissue forming new blood vessels in mice

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Macrophages trigger stem cells for wound repair and regeneration

Sydney Morning Herald - 11-Feb-2021

Macrophages and stem cell interaction promotes muscle repair in zebrafish and mice models

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Bones could soon be 3D printed directly into patient's body

IEEE Spectrum - 28-Jan-2021

Ceramic ink printing synthetic bones offers future scope for handheld printers

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Boosting NAD+ reverses muscle ageing and associated diseases

Medical Xpress - 19-Jan-2021

Drugs boosting NAD+ target toxic proteins by turning on the mitochondrial function

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Progress on human ageing studies with Dunkin Hartley guinea pig

Colorado State University - 06-Jan-2021

Animal model studies that help in better understanding musculoskeletal ageing

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Clene's neurotherapeutics using metals enter human trials

Longevity Technology - 05-Jan-2021

Novel approach with gold nanocatalyst technology to reverse neurodegenerative disease

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Protein that regulates muscle function in ageing discovered

Stanford School of Medicine - 10-Dec-2020

Blocking it improved muscle strength & function while endurance was also boosted in mice

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AKG supplements prevent bone diseases in the old

Longevity Technology - 02-Dec-2020

AKG with antiaging benefits is now proved to counter osteoporosis in rodents

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Veganism may weaken your bones and lead to fractures

Independent - 23-Nov-2020

Vegans are at higher risk of broken bones when compared to people who eat meat

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Glutamine- the choice for injured or aged muscles

Medical Xpress - 29-Oct-2020

Researchers found an advancement in healing muscles with glutamine

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Early detection of osteoarthritis using machine learning

National Institutes of Health (NIH) - 07-Oct-2020

Cartilage maps along with machine learning algorithms predict arthritic cases

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A milestone towards developing a drug for Multiple Sclerosis

Guardian - 25-Sep-2020

Drug shows repaired coating around nerves but side effects prevent its use

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Treating space induced muscle and bone loss in mice

Astronomy - 09-Sep-2020

We can probably take space holidays without worrying about muscle wasting in future

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Old mice show improved muscle function with gene therapy

Lifespan.io (LEAF) - 27-Aug-2020

A single injection could treat motor diseases of the aged but needs more human studies

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A new technique of accelerating nerve regeneration in animals

Folio - 19-Aug-2020

Will help trauma patients recover faster and better from nerve injuries

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Reason examines the failure of Unity Biotechnology's phase 2 senolytics trial

Fight Aging! - 18-Aug-2020

Disappointing first result - but lessons learnt and plenty of other strategies available

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Method to regenerate joint cartilage in adults, discovered

Stanford School of Medicine - 17-Aug-2020

Principle tested and a success in mice and humans, to ease arthritis in the future

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Hormone in bone restores memory and ability to exercise in old mice

Guardian - 04-Jul-2020

Exercising regularly increases this hormone and benefits muscle and brain

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Cellular pathway and mechanism leading to osteoporosis

Lifespan.io (LEAF) - 09-Jun-2020

Confirmed in murine and human cell study, findings can aid development of new treatments

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BSRA sponsors funding to repair bone fractures in the aged

British Society for Research on Ageing (BSRA) - 01-Jun-2020

Chernajovsky Foundation with BSRA funds for PEPITEM molecule to treat fractures

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Mice blood proteome analysis reveals new therapeutic target for osteoporosis

Lifespan.io (LEAF) - 26-May-2020

A different perspective for preventing age-related bone loss that affects many

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Combination of two molecules, a potential treatment for osteoarthritis

Lifespan.io (LEAF) - 19-May-2020

Raises hope to end the extensive physical and psychological suffering the condition brings

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Follistatin gene therapy to combat osteoarthritis and obesity

Next Big Future - 16-May-2020

This new approach doubled muscle mass in mice, reduced its fat

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Altering macrophage epigenetics to prevent lumbar disc degeneration

Lifespan.io (LEAF) - 04-May-2020

Findings can lead future treatments for age-related conditions caused by inflammaging

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Scientists reverse cellular ageing while maintaining cell's identity

New York Times - 24-Mar-2020

How long will it take until this can be applied to human cells inside the body?

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Revolutionizing 3D handheld bioprinter

UConn Today - 27-Feb-2020

Bioprinter was successfully tested on mice, significant muscle hypertrophy was recorded

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Regrowing nerves with a biodegradable device in macaques

Futurism - 23-Jan-2020

Bridging long nerve gaps from injuries; soon to enter human trials in 2021

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UNITY Biotechnology expands trial of osteoarthritis senolytic

UNITY Biotechnology - 22-Jan-2019

Initial results must be promising to enrol more patients at highest dosage

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UNITY Treats First Patient with UBX0101

UNITY Biotechnology - 25-Jun-2018

The company is going to test a new Senolytic drug in human trials

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Treating Osteoarthritis by Removing Senescent Cells

Lifespan.io (LEAF) - 03-May-2017

Researchers used local clearance of senescent cells (in mice) to reduce the development of post-traumatic osteoarthritis and encourage tissue regeneration.

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