Muscle strength linked to longer life for people aged 90 and above
Live Forever Club - 25-Oct-2024Even small improvements in strength can have significant health benefits
Musculoskeletal System News Archive
AI to assist doctors in spotting hidden fractures on X-rays
BBC - 22-Oct-2024New technology aims to improve diagnosis speed and accuracy in busy emergency departments
AI analysis identified unique gene as a key player in muscle ageing
Nottingham Trent University (NTU) - 17-Oct-2024Findings offer hope for future therapies targeting sarcopenia and muscle loss
Dr. Sajad Zalzala reports on PEARL rapamycin trial results
Live Forever Club - 28-Aug-2024Safety of rapamycin looks good and lean muscle mass among biomarkers trending towards improvement
Stem cell injection shows promise in reducing knee osteoarthritis pain
New Atlas - 28-Jul-202475% of participants experienced clinical improvement in both pain and function
Oisín Biotechnologies has raised $15 million to develop genetic medicines
Longevity Technology - 25-Jul-2024Funding will primarily be used to advance therapies focused on muscle growth
Senolytic drugs show promise for bone health in postmenopausal women
Mayo Clinic - 02-Jul-2024But, senolytic therapy may not be a universal solution for age-related bone loss
NHS to launch first AI-run physiotherapy clinic to cut waiting times
The Guardian - 09-Jun-2024Initial trials show promising results with improved symptoms and reduced waiting
Eye muscles known as 'extraocular muscles' are remarkably resistant to aging
Live Forever Club - 30-May-2024Findings hint at potential breakthroughs in muscle therapy
Ancient wisdom meets modern science: Inorganic biomaterials heal bones and muscles
Phys.org - 30-May-2024Nanosilicates shown to provide safer, more precise tissue regeneration than current methods
Paralyzed surfer regains mobility using stem cells in belly fat
Independent - 03-Apr-2024Experimental stem cell therapy offers hope for spinal cord injury patients
Gut bacteria and blood molecules offer clues to why grip strength weakens with age
Live Forever Club - 21-Feb-2024Research opens doors for future interventions to prevent muscle loss
Rejuvenate Biomed's potential drug candidate combats sarcopenia in older adults
Rejuvenate Biomed - 21-Feb-2024Phase 1b trial shows RJx-01's ability to improve muscle strength, function, and fatigue resistance
Rejuvenate Bio partners with animal company to develop gene therapy for canine osteoarthritis
Biospace - 14-Feb-2024Single dose injection targets root causes, offering long-term relief & improved quality of life
Daily choices like exercise, diet, and even how you breathe affect your mitochondria
Live Forever Club - 09-Feb-2024Making small changes to your lifestyle can have a significant impact on health
A new medicine called JUV-161 might help people with DM1, a rare muscle disease
Business Wire - 23-Jan-2024It improved muscles and slowed down the disease in animals
Astronauts and the elderly might get special shots to keep their bones strong
Medical Xpress - 22-Jan-2024The potential for human trials starting by 2025 suggests rapid progress
Activating SIRT6, a DNA repair protein, reduces damage in ageing cells
Live Forever Club - 01-Jan-2024SIRT6 activation may be a potential therapeutic target for osteoarthritis
Evolved.Bio pioneers a scaffold-free method to regenerate muscle tissue
Phys.org - 10-Nov-2023Offering hope for individuals with significant muscle damage
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Eating less, living longer: the positive effects of calorie restriction
International Institute on Ageing (INIA) - 16-Oct-2023Modest calorie reduction can activate genes for healthy ageing
Stem cell therapy gives arthritic gorilla new lease of life
Interesting Engineering - 03-Sep-2023Liesel the gorilla is now walking again after receiving Stem CellX treatment
Nearly one billion people may suffer from osteoarthritis by 2050
Independent - 21-Aug-2023Ageing and obesity are key drivers of the rise in cases
Vegetarian diet may increase hip fracture risk by 50%
Medical News Today - 08-Aug-2023Well-balanced diet with plenty of protein and key nutrients could reduce risk of bone fractures
Signalling pathways in aged cells found to impair the ability to repair and regenerate muscle cells
Independent - 07-Aug-2023Study results offer insights on future drug discovery for disease related to muscle ageing
Metformin may minimize muscle loss in extended periods of bed rest
Lifespan.io (LEAF) - 24-Jul-2023Improvements seen in muscle size and collagen deposits in older people with atrophy
Revitalizing ageing stem cells: Unveiling the key to lasting youthfulness
Lifespan.io (LEAF) - 05-Jun-2023Combination of factors that rejuvenate stem cells holds promise for aging and muscle-wasting diseases
Revolutionary bio-inspired molecules accelerate bone healing: a breakthrough for regenerative medicine
TU Dresden (University of Technology) - 28-Apr-2023Novel molecules enhance bone regeneration in mice by 50%, paving the way for treatments for bone fractures and related conditions
AKL Therapeutics’ investigational oral senotherapeutics drug APPA beneficial for osteoarthritis
Longevity Technology - 20-Mar-2023Senescent cells have become one of the most promising targets for healthy aging research
Restoring glutathione -potential therapy could prevent old impaired stem cells from ever developing
UCLA Health - 27-Feb-2023Higher levels of glutathione better at muscle repair while low levels of the same are bad at it
Exploring mesenchymal stem cell derived exosomal therapy as intervertebral disc degeneration cure
Live Forever Club - 08-Feb-2023MSCExos shown to improve osteoporosis by promoting osteoclast cell proliferation and formation of blood vessels
Taking aspirin daily may increase the risk of dangerous falls for older people
New Scientist - 07-Nov-2022Caution advised in prescribing to elderly without heart risks
Phase 2 clinical trial of lead drug candidate MYMD-1- a therapy for delaying aging
Business Wire - 26-Jul-2022Sarcopenia drug trial shows no evidence of toxicity or safety issues
Urolithin A can increase mitochondrial health in living joint tissue and improved mobility
Business Wire - 07-Jul-2022Mitopure can improve mitochondrial health and counteract age-related muscle function decline
Sarconeos BIO101 in development for the treatment of Sarcopenia by Biophytis
Yahoo! finance - 27-Jun-2022SARA-INT Phase 2 study and SARA Phase 3 study milestones in developing sarconeos
Scientists built a functional human tendon using 3D cryobioprinting
3D Printing Industry - 07-Feb-2022A breakthrough technique to print complex tissues that can be stored for later use
A natural cholesterol metabolite with senolytic effect in mice and humans
Buck Institute - 02-Feb-2022New class of senotherapeutic drugs that could possibly target various diseases and ageing
Senolytics promotes wound healing in the aged but not in young mice
Lifespan.io (LEAF) - 22-Dec-2021Dasatinib plus quercetin slow down muscle regeneration in young mice
MyMD Pharmaceuticals begins phase 2 trial of TNF-inhibitor in January 2022
Longevity Technology - 14-Dec-2021Potential oral treatment to prevent sarcopenia and frailty, and extend healthy lifespan
Valuable insight into the influence of age-associated humoral factors
Genetic Engineering & Biotechnology News (GEN) - 07-Dec-2021An injection of extracellular vesicles improve muscle regeneration
A powerful platform to facilitate rehabilitation and musculoskeletal diseases
Medgadget - 24-Nov-2021Thin, wireless, battery-free and multimodal musculoskeletal biointerfaces
Senolytic cocktail reduces age-related spinal disc degeneration in mice
Lifespan.io (LEAF) - 21-Sep-2021Dasatinib and quercetin combo preserves spinal discs to target age-related back pain
A single protein reversed senescence in skeletal muscle cells
University at Buffalo - 17-Sep-2021NANOG targets multiple ageing mechanisms - insights may help develop new therapies for age-related disorders
Role of Neuromuscular junction in ageing and neuro muscular diseases
Fight Aging! - 17-Aug-2021Neuromuscular junction: A potential therapeutic target in neuromuscular injury
Safer and faster treatment of tendon injuries with stem-cell fat grafts
Genetic Engineering & Biotechnology News (GEN) - 17-Aug-2021Tendons regain their original healthy condition within 2 months of therapy in sheep
Skeletal stem cells delay bone healing and foster inflammageing in older people
Medical Xpress - 12-Aug-2021Treating with BMP2 and Csf1 antagonist in mice restored youthfulness to the aged skeletal system
Clearing out aged cells with senolytics can relieve jaw pain
University of Connecticut (UConn) - 07-Jul-2021Senolytics for cartilage and bone regeneration in jaw joints, proven effective in mice
Zoledronate - accidental discovery of drug use for life extension
Lifespan.io (LEAF) - 30-Jun-2021Too early to tell whether off-patent drug's effects in fruit flies will be seen in humans
Returning function to paralysed upper limbs is the primary goal of Orthocell trial
The Market Herald - 21-Jun-2021Peripheral nerve repair could benefit 3 million patients every year
Natural compound may help treat intervertebral disc degeneration
Lifespan.io (LEAF) - 12-May-2021DHE slowed senescence in intervertebral discs of mice; but its use in anti-aging is still questionable
Low magnitude vibration to prevent/delay age-related bone loss in rats
Lifespan.io (LEAF) - 05-May-2021Vibration treatment eliminates senescence of bone cells - may not be applicable to other tissues
Klotho protein reversed muscle ageing in old, but not older mice
eLife Sciences - 20-Apr-2021Potential future treatment strategy to prevent sarcopenia when supplemented at a young age
Supplementation with nicotinamide riboside slows age-related bone loss
Fight Aging! - 14-Apr-2021Long-term use of this supplement boosts NAD+ levels, lowering the risk of osteoporosis in mice
A man-made molecule that helps repair and regenerate muscle tissue
EurekAlert! - 23-Mar-2021Givinostat induces stem cells to produce muscle making cells - promising therapy for age-related muscle loss
Stretchable bioelectronics with silver hydrogel composite
Medgadget - 15-Mar-2021Electrically conductive, flexible hydrogels to open the door for wearable electronics and soft robots
Richard Ljuhar sheds light on AI-driven ImageBiopsy lab
Medical Expo - 10-Mar-2021Highlights the diagnostic accuracy of musculoskeletal diseases using AI processed medical imaging
Single gene therapy injection halts spinal muscular atrophy
BBC - 08-Mar-2021Becomes most expensive drug ever approved for the NHS - but no lifetime costs
Rejuvenate Biomed raises 3.2 million euros for anti-ageing drugs
PharmiWeb.com - 02-Mar-2021Accelerates clinical trial plans for its lead candidate Rlx-01 targeting age-related muscle failure
Genetically engineered cartilage combats inflammatory arthritis
National Institute on Aging (NIA) - 24-Feb-2021Engineered cells produce anti-inflammatory drug that helps reduce stress-related cartilage damage
Artificial muscles in regeneration of damaged skeletal muscle
Science Daily - 21-Feb-2021Hybrid constructs help regrow muscle tissue forming new blood vessels in mice
Macrophages trigger stem cells for wound repair and regeneration
Sydney Morning Herald - 11-Feb-2021Macrophages and stem cell interaction promotes muscle repair in zebrafish and mice models
Bones could soon be 3D printed directly into patient's body
IEEE Spectrum - 28-Jan-2021Ceramic ink printing synthetic bones offers future scope for handheld printers
Boosting NAD+ reverses muscle ageing and associated diseases
Medical Xpress - 19-Jan-2021Drugs boosting NAD+ target toxic proteins by turning on the mitochondrial function
Progress on human ageing studies with Dunkin Hartley guinea pig
Colorado State University - 06-Jan-2021Animal model studies that help in better understanding musculoskeletal ageing
Clene's neurotherapeutics using metals enter human trials
Longevity Technology - 05-Jan-2021Novel approach with gold nanocatalyst technology to reverse neurodegenerative disease
Protein that regulates muscle function in ageing discovered
Stanford School of Medicine - 10-Dec-2020Blocking it improved muscle strength & function while endurance was also boosted in mice
AKG supplements prevent bone diseases in the old
Longevity Technology - 02-Dec-2020AKG with antiaging benefits is now proved to counter osteoporosis in rodents
Veganism may weaken your bones and lead to fractures
Independent - 23-Nov-2020Vegans are at higher risk of broken bones when compared to people who eat meat
Glutamine- the choice for injured or aged muscles
Medical Xpress - 29-Oct-2020Researchers found an advancement in healing muscles with glutamine
Early detection of osteoarthritis using machine learning
National Institutes of Health (NIH) - 07-Oct-2020Cartilage maps along with machine learning algorithms predict arthritic cases
A milestone towards developing a drug for Multiple Sclerosis
Guardian - 25-Sep-2020Drug shows repaired coating around nerves but side effects prevent its use
Treating space induced muscle and bone loss in mice
Astronomy - 09-Sep-2020We can probably take space holidays without worrying about muscle wasting in future
Old mice show improved muscle function with gene therapy
Lifespan.io (LEAF) - 27-Aug-2020A single injection could treat motor diseases of the aged but needs more human studies
A new technique of accelerating nerve regeneration in animals
Folio - 19-Aug-2020Will help trauma patients recover faster and better from nerve injuries
Reason examines the failure of Unity Biotechnology's phase 2 senolytics trial
Fight Aging! - 18-Aug-2020Disappointing first result - but lessons learnt and plenty of other strategies available
Method to regenerate joint cartilage in adults, discovered
Stanford School of Medicine - 17-Aug-2020Principle tested and a success in mice and humans, to ease arthritis in the future
Hormone in bone restores memory and ability to exercise in old mice
Guardian - 04-Jul-2020Exercising regularly increases this hormone and benefits muscle and brain
Cellular pathway and mechanism leading to osteoporosis
Lifespan.io (LEAF) - 09-Jun-2020Confirmed in murine and human cell study, findings can aid development of new treatments
BSRA sponsors funding to repair bone fractures in the aged
British Society for Research on Ageing (BSRA) - 01-Jun-2020Chernajovsky Foundation with BSRA funds for PEPITEM molecule to treat fractures
Mice blood proteome analysis reveals new therapeutic target for osteoporosis
Lifespan.io (LEAF) - 26-May-2020A different perspective for preventing age-related bone loss that affects many
Combination of two molecules, a potential treatment for osteoarthritis
Lifespan.io (LEAF) - 19-May-2020Raises hope to end the extensive physical and psychological suffering the condition brings
Follistatin gene therapy to combat osteoarthritis and obesity
Next Big Future - 16-May-2020This new approach doubled muscle mass in mice, reduced its fat
Altering macrophage epigenetics to prevent lumbar disc degeneration
Lifespan.io (LEAF) - 04-May-2020Findings can lead future treatments for age-related conditions caused by inflammaging
Scientists reverse cellular ageing while maintaining cell's identity
New York Times - 24-Mar-2020How long will it take until this can be applied to human cells inside the body?
Revolutionizing 3D handheld bioprinter
UConn Today - 27-Feb-2020Bioprinter was successfully tested on mice, significant muscle hypertrophy was recorded
Regrowing nerves with a biodegradable device in macaques
Futurism - 23-Jan-2020Bridging long nerve gaps from injuries; soon to enter human trials in 2021
UNITY Biotechnology expands trial of osteoarthritis senolytic
UNITY Biotechnology - 22-Jan-2019Initial results must be promising to enrol more patients at highest dosage
UNITY Treats First Patient with UBX0101
UNITY Biotechnology - 25-Jun-2018The company is going to test a new Senolytic drug in human trials
Treating Osteoarthritis by Removing Senescent Cells
Lifespan.io (LEAF) - 03-May-2017Researchers used local clearance of senescent cells (in mice) to reduce the development of post-traumatic osteoarthritis and encourage tissue regeneration.
